2023
PERSONALIZED AND TYPICAL CONCURRENT RISK: JOINT MODELS OF RECURRENT OUTCOMES AND MORTALITY BY RACE/ETHNICITY
Allore H, McAvay G, Vander Wyk B, Han L, Quiñones A. PERSONALIZED AND TYPICAL CONCURRENT RISK: JOINT MODELS OF RECURRENT OUTCOMES AND MORTALITY BY RACE/ETHNICITY. Innovation In Aging 2023, 7: 231-231. PMCID: PMC10736438, DOI: 10.1093/geroni/igad104.0759.Peer-Reviewed Original ResearchMultiple chronic conditionsChronic conditionsRisk factorsConcurrent riskSociodemographic risk factorsPoor health outcomesHuman Services initiativeHealthcare system policiesRace/ethnicityFunctional statusHigh riskHealth outcomesHealth statusHealth servicesAverage riskPatient trajectoriesPopulation subgroupsOutcomesRecurrent outcomesRiskCohort levelConcurrent outcomesRandom intercept termLongitudinal effectsMultiple outcomes
2020
Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures
Zhao Y, Amodio M, Vander Wyk B, Gerritsen B, Kumar MM, van Dijk D, Moon K, Wang X, Malawista A, Richards MM, Cahill ME, Desai A, Sivadasan J, Venkataswamy MM, Ravi V, Fikrig E, Kumar P, Kleinstein SH, Krishnaswamy S, Montgomery RR. Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures. PLOS Neglected Tropical Diseases 2020, 14: e0008112. PMID: 32150565, PMCID: PMC7082063, DOI: 10.1371/journal.pntd.0008112.Peer-Reviewed Original ResearchConceptsZika virusCell subsetsDengue virusConcurrent dengue infectionInnate cell responsesInnate immune signaturesVirus-infected individualsDivergent clinical outcomesMosquito-borne human pathogenIntact immune responsePre-existing infectionInnate cell typesSingle-cell immune profilingPublic health importanceCell typesImmune signaturesVirus patientsWest Nile virusAcute patientsClinical outcomesImmune profilingDengue infectionImmune statusFunctional statusImmune cells