Featured Publications
Epigenome-Wide Analysis Reveals DNA Methylation Alteration in ZFP57 and Its Target RASGFR2 in a Mexican Population Cohort with Autism
Aspra Q, Cabrera-Mendoza B, Morales-Marín ME, Márquez C, Chicalote C, Ballesteros A, Aguilar M, Castro X, Gómez-Cotero A, Balboa-Verduzco AM, Albores-Gallo L, Nafate-López O, Marcín-Salazar CA, Sánchez P, Lanzagorta-Piñol N, López-Armenta FO, Nicolini H. Epigenome-Wide Analysis Reveals DNA Methylation Alteration in ZFP57 and Its Target RASGFR2 in a Mexican Population Cohort with Autism. Children 2022, 9: 462. PMID: 35455506, PMCID: PMC9025761, DOI: 10.3390/children9040462.Peer-Reviewed Original ResearchDNA methylationGenome-wide differencesIllumina 450k arrayDNA methylation patternsDNA methylation profilesDNA methylation studiesDNA methylation alterationsWide analysisMethylation patternsEnvironmental factorsMethylation alterationsMethylation profilesMethylation studiesDifferent tissuesMethylationASD etiologyASD pathophysiologyComplex neurodevelopmental disorderMolecular alterationsEpithelium cellsNeurodevelopmental disordersComplex interactionsZFP57RasGRF2Diversity
2024
Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder
Mirza S, Lima C, Del Favero-Campbell A, Rubinstein A, Topolski N, Cabrera-Mendoza B, Kovács E, Blumberg H, Richards J, Williams A, Wemmie J, Magnotta V, Fiedorowicz J, Gaine M, Walss-Bass C, Quevedo J, Soares J, Fries G. Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder. Translational Psychiatry 2024, 14: 70. PMID: 38296944, PMCID: PMC10831084, DOI: 10.1038/s41398-024-02760-y.Peer-Reviewed Original ResearchConceptsEpigenome-wide association studiesDifferentially methylated regionsDifferentially methylated positionsAssociation studiesCo-methylation network analysisBipolar disorderDNA methylation patternsSuicide attemptsReplication cohortHistory of SAGene ontology analysisSignificant CpG sitesMethylation patternsDNA methylationCpG sitesOntology analysisImmune-related genesEnrichment analysisNon-psychiatric controlsCalcium signalingGenesDNAClinical interviewSA historyNetwork analysis