Schwann Cell Transplantation Improves Reticulospinal Axon Growth and Forelimb Strength after Severe Cervical Spinal Cord Contusion
Schaal SM, Kitay BM, Cho KS, Lo TP, Barakat DJ, Marcillo AE, Sanchez AR, Andrade CM, Pearse DD. Schwann Cell Transplantation Improves Reticulospinal Axon Growth and Forelimb Strength after Severe Cervical Spinal Cord Contusion. Cell Transplantation 2007, 16: 207-228. PMID: 17503734, DOI: 10.3727/000000007783464768.Peer-Reviewed Original ResearchConceptsSpinal cord injuryAxon growthNeuroprotective efficacyCervical spinal cord contusionInjury/graft siteCell bodiesThoracic spinal cord injurySchwann cell transplantationSpinal cord contusionThoracic spinal cordAdult female Fischer ratsFemale Fischer ratsSchwann cell implantationUpper limb strengthSignificant behavioral improvementCervical contusionInjury epicenterCord contusionUpper body strengthWeeks postinjuryBBB scoresSC implantsSupraspinal axonsCell transplantationCord injury