2024
DNA Methylation Classes of Stage II and III Primary Melanomas and Their Clinical and Prognostic Significance
Conway K, Edmiston S, Vondras A, Reiner A, Corcoran D, Shen R, Parrish E, Hao H, Lin L, Kenney J, Ilelaboye G, Kostrzewa C, Kuan P, Busam K, Lezcano C, Lee T, Hernando E, Googe P, Ollila D, Moschos S, Gorlov I, Amos C, Ernstoff M, Cust A, Wilmott J, Scolyer R, Mann G, Vergara I, Ko J, Rees J, Yan S, Nagore E, Bosenberg M, Rothberg B, Osman I, Lee J, Saenger Y, Bogner P, Thompson C, Gerstenblith M, Holmen S, Funchain P, Brunsgaard E, Depcik-Smith N, Luo L, Boyce T, Orlow I, Begg C, Berwick M, Thomas N, Berwick M, Luo L, Boyce T, Reynolds A, Wiggins C, Thomas N, Conway K, Edmiston S, Ollila D, Hao H, Parrish E, Googe P, Moschos S, Corcoran D, Vondras A, Tsai Y, Lin L, Shen R, Begg C, Arora A, Seshan V, Reiner A, Kostrzewa C, Busam K, Orlow I, Lezcano C, Kenney J, Sadeghi K, O'Connell K, Ilelaboye G, Parmar H, Leong S, Corrales S, Scolyer R, Cust A, Wilmott J, Mann G, Shang P, Burke H, Ferguson P, Jakrot V, Lee T, Hernando E, Osman I, Hanniford D, Argibay D, Moran U, Heguy A, Ramaswami S, Amos C, Gorlov I, Zhu D, Ernstoff M, Bogner P, Lee J, Rees J, Yan S, Gerstenblith M, Thompson C, Ko J, Funchain P, Ngo P, Bosenberg M, Gould Rothberg B, Panse G, Saenger Y, Fullerton B, Holmen S, Colman H, Brunsgaard E, Wada D, Nagore E, Manrique-Silva E, Requena C, Traves V, Millan-Esteban D, Rainka M. DNA Methylation Classes of Stage II and III Primary Melanomas and Their Clinical and Prognostic Significance. JCO Precision Oncology 2024, 8: e2400375. PMID: 39509669, DOI: 10.1200/po-24-00375.Peer-Reviewed Original ResearchConceptsAmerican Joint Committee on CancerCpG island methylator phenotypePrimary melanomaBreslow thicknessMethylation classClinicopathological characteristicsN stageRisk of melanoma-related deathLow methylationStage IIRetrospective case-control studyCutaneous primary melanomaHigher AJCC stagePrimary cutaneous melanomaHigher N stageMelanoma-related deathDNA methylation classDied of melanomaMitotic indexCase-control studyIII patientsClinicopathological factorsCpG island hypermethylationPrognostic significanceAJCC stage
2014
Red meat and fruit intake is prognostic among patients with localized cutaneous melanomas more than 1mm thick
Rothberg BE, Bulloch K, Fine J, Barnhill R, Berwick M. Red meat and fruit intake is prognostic among patients with localized cutaneous melanomas more than 1mm thick. Cancer Epidemiology 2014, 38: 599-607. PMID: 25194935, PMCID: PMC4229370, DOI: 10.1016/j.canep.2014.08.005.Peer-Reviewed Original ResearchConceptsMelanoma-specific survivalLocalized cutaneous melanomaFruit consumptionPost-diagnostic measuresDaily fruit consumptionModifiable lifestyle behaviorsRed meatBreslow thicknessCutaneous melanomaAssociated with melanoma-specific survivalRed meat consumptionAssociated with worse outcomesSurvivorship periodLifestyle behaviorsCancer survivorsPhysical activityTobacco cessationFruit intakeNon-therapeutic interventionsTime of diagnosisCox proportional hazardsHigh fish consumptionDietary choicesIndex melanomaIndependent associations
2013
Marginal and Joint Distributions of S100, HMB-45, and Melan-A Across a Large Series of Cutaneous Melanomas
Viray H, Bradley WR, Schalper KA, Rimm DL, Rothberg BE. Marginal and Joint Distributions of S100, HMB-45, and Melan-A Across a Large Series of Cutaneous Melanomas. Archives Of Pathology & Laboratory Medicine 2013, 137: 1063-73. PMID: 23899062, PMCID: PMC3963468, DOI: 10.5858/arpa.2012-0284-oa.Peer-Reviewed Original ResearchConceptsHMB-45Primary tumorCutaneous melanomaLarge seriesMelanoma-specific survivalMelanoma primary tumorsGroup of antigensLarge tissue microarrayClinicopathologic covariatesClinicopathologic criteriaPrognostic relevanceHistopathologic profileClinicopathologic correlatesAntigen expressionClinicopathologic parametersMelanoma markersTissue microarrayPositive expressionSurvival analysisMelanomaMelanS100Melanoma cellsBivariate associationsSignificant differences
2010
Gestational weight gain and subsequent postpartum weight loss among young, low-income, ethnic minority women
Rothberg BE, Magriples U, Kershaw TS, Rising SS, Ickovics JR. Gestational weight gain and subsequent postpartum weight loss among young, low-income, ethnic minority women. American Journal Of Obstetrics And Gynecology 2010, 204: 52.e1-52.e11. PMID: 20974459, PMCID: PMC3011029, DOI: 10.1016/j.ajog.2010.08.028.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBlack or African AmericanConnecticutFemaleGeorgiaGuidelines as TopicHispanic or LatinoHumansHypertension, Pregnancy-InducedNational Academies of Science, Engineering, and Medicine, U.S., Health and Medicine DivisionObesityOverweightPostpartum PeriodPovertyPregnancyPregnancy Trimester, SecondPregnancy Trimester, ThirdReference ValuesSmokingUnited StatesWeight GainWeight LossWhite PeopleYoung AdultConceptsPostpartum weight lossWeight change trajectoriesGestational weight gainWeight gainWeight lossEthnic minority womenExcessive pregnancy weight gainLow-income ethnic minority womenLongitudinal mixed modelingPregnancy weight gainPregnancy-induced hypertensionMedical record reviewOverweight/obeseBody mass indexWeight management interventionsMinority womenInstitute of MedicineSingleton infantsGestational weightMass indexMedicine guidelinesRecord reviewThird trimesterPrenatal careClinical recommendations
2009
Melanoma Prognostic Model Using Tissue Microarrays and Genetic Algorithms
Rothberg BE, Berger AJ, Molinaro AM, Subtil A, Krauthammer MO, Camp RL, Bradley WR, Ariyan S, Kluger HM, Rimm DL. Melanoma Prognostic Model Using Tissue Microarrays and Genetic Algorithms. Journal Of Clinical Oncology 2009, 27: 5772-5780. PMID: 19884546, PMCID: PMC2792999, DOI: 10.1200/jco.2009.22.8239.Peer-Reviewed Original ResearchConceptsHigh-risk group
2008
Prognostic Significance of Cadherin-Based Adhesion Molecules in Cutaneous Malignant Melanoma
Kreizenbeck GM, Berger AJ, Subtil A, Rimm DL, Rothberg BE. Prognostic Significance of Cadherin-Based Adhesion Molecules in Cutaneous Malignant Melanoma. Cancer Epidemiology Biomarkers & Prevention 2008, 17: 949-958. PMID: 18398036, PMCID: PMC3312613, DOI: 10.1158/1055-9965.epi-07-2729.Peer-Reviewed Original Research
2003
Re: Hemorrhagic angiomyolipoma and tuberous sclerosis complex: a case report. Recognizing the needs of a growing population of adults with tuberous sclerosis complex.
Rothberg B. Re: Hemorrhagic angiomyolipoma and tuberous sclerosis complex: a case report. Recognizing the needs of a growing population of adults with tuberous sclerosis complex. Connecticut Medicine 2003, 67: 313-4. PMID: 12802849.Peer-Reviewed Original Research
1992
Reversed-phase liquid chromatographic purification and isolation of a radio-iodinated selective probe for mu opioid receptors in the brain
Miller M, Gould B, Joshi D, Bennett H, James S, Billiar R. Reversed-phase liquid chromatographic purification and isolation of a radio-iodinated selective probe for mu opioid receptors in the brain. Journal Of Neuroscience Methods 1992, 41: 93-99. PMID: 1314320, DOI: 10.1016/0165-0270(92)90052-f.Peer-Reviewed Original ResearchConceptsAdrenocorticotropin hormoneBlock ligand bindingOpioid receptorsMouse corpus striatumN-methyl-Phe4Nucleus accumbens septiGly-ol5 enkephalinDiagonal band of BrocaDecreased ligand bindingLight microscopic autoradiographyPresence of agonistAccumbens septiHigh-performance liquid chromatography columnLigand bindingD-Ala2Beta-endorphinCorpus striatumRadioligand bindingLiquid chromatography columnDiagonal bandCingulate cortexAnalysis of ligandsIncreasing dosesIodine reagentsLiquid chromatographic purification
1989
Aging and long-term ovariectomy alter the cytoarchitecture of the hypothalamic-preoptic area of the C57BL/6J mouse
Miller M, Gould B, Nelson J. Aging and long-term ovariectomy alter the cytoarchitecture of the hypothalamic-preoptic area of the C57BL/6J mouse. Neurobiology Of Aging 1989, 10: 683-690. PMID: 2628780, DOI: 10.1016/0197-4580(89)90005-5.Peer-Reviewed Original ResearchConceptsLong-term ovariectomyArcuate nucleusPreoptic areaNeuronal densitySuprachiasmatic nucleusIntact miceAged female rodentsSizes of gliaHypothalamic-preoptic areaDensity of blood vesselsFemale rodentsMonths of ageArea of nucleolusOvariectomized miceQuantitative light microscopyEffects of agePerikaryal areaOld miceNeuronal areasCoronal sectionsOvariectomyMiceReproductive functionBlood vesselsAge