2023
Association of Age and Frailty With 30‐Day Outcomes Among Patients Undergoing Oral Cavity Cancer Surgery
Boyi T, Williams L, Kafle S, Roche A, Judson B. Association of Age and Frailty With 30‐Day Outcomes Among Patients Undergoing Oral Cavity Cancer Surgery. Otolaryngology 2023, 169: 1523-1532. PMID: 37595108, DOI: 10.1002/ohn.476.Peer-Reviewed Original ResearchConceptsNational Quality Improvement Program databaseFrailty index scoreAdverse eventsSurgeons National Quality Improvement Program databaseIndex scoreOral cavity cancer surgeryQuality Improvement Program databaseRetrospective cross-sectional analysisHigher mFI scoresPostoperative adverse eventsImprovement Program databaseChronic obstructive diseaseCongestive heart failureFree flap reconstructionAssociation of ageImpact of ageCross-sectional analysisMore comorbiditiesOSCC resectionAnesthesiologists classificationPerioperative outcomesComposite resectionNeck dissectionHeart failureMFI score
2021
Assessing Human Papillomavirus Awareness and the Role of Oropharyngeal Squamous Cell Carcinoma Education on Improving Intention to Vaccinate
Torabi SJ, Su‐Velez B, Kasle DA, Yarbrough WG, St. John M, Judson BL. Assessing Human Papillomavirus Awareness and the Role of Oropharyngeal Squamous Cell Carcinoma Education on Improving Intention to Vaccinate. The Laryngoscope 2021, 132: 528-537. PMID: 34383306, DOI: 10.1002/lary.29805.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlphapapillomavirusCarcinoma, Squamous CellChildCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansIntentionMaleMiddle AgedOropharyngeal NeoplasmsPapillomavirus VaccinesPatient Acceptance of Health CarePatient Education as TopicSocioeconomic FactorsSurveys and QuestionnairesUnited StatesYoung AdultConceptsOropharyngeal squamous cell carcinomaHuman papillomavirusCross-sectional surveyHPV's roleRole of HPVSquamous cell carcinomaHuman papillomavirus (HPV) awarenessGeneral population's knowledgeOnline cross-sectional surveyHPV vaccinationCell carcinomaGeneral populationRacial disparitiesU.S. populationPopulation knowledgeBlack individualsMultivariate regressionVaccinationPapillomavirusVaccinatorsProfessional sourcesCarcinomaVaccinePopulationPublic knowledge
2020
Outpatient Otolaryngology in the Era of COVID‐19: A Data‐Driven Analysis of Practice Patterns
Kasle DA, Torabi SJ, Savoca EL, Judson BL, Manes RP. Outpatient Otolaryngology in the Era of COVID‐19: A Data‐Driven Analysis of Practice Patterns. Otolaryngology 2020, 163: 138-144. PMID: 32393101, PMCID: PMC7218354, DOI: 10.1177/0194599820928987.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBetacoronavirusChildChild, PreschoolCoronavirus InfectionsCOVID-19Data AnalysisDisease Transmission, InfectiousFemaleHumansMaleMiddle AgedOtolaryngologistsOtorhinolaryngologic DiseasesOutpatientsPandemicsPneumonia, ViralPractice Patterns, Physicians'Retrospective StudiesSARS-CoV-2TelemedicineUnited StatesYoung AdultConceptsDivision of OtolaryngologyTelehealth visitsOlder adultsHospital policy changesSingle-institution studyCoronavirus disease 2019Quantity of patientsOutpatient otolaryngologyRetrospective reviewAcute carePerson visitsOutpatient appointmentsPractice patternsDisease 2019Week 1Week 3VisitsYoung adultsOtolaryngologyCOVID-19Completion ratesOtolaryngologistsAdultsAssociated increaseTelehealth
2019
Clinical characteristics and treatment‐associated survival of head and neck Ewing sarcoma
Torabi SJ, Izreig S, Kasle DA, Benchetrit L, Salehi PP, Judson BL. Clinical characteristics and treatment‐associated survival of head and neck Ewing sarcoma. The Laryngoscope 2019, 130: 2385-2392. PMID: 31774563, DOI: 10.1002/lary.28412.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseOverall survivalLocal therapyRare malignancySurvival analysisPredictors of OSKaplan-Meier survival analysisNeck Ewing sarcomaDistant metastatic diseaseNon-metastatic diseaseMultivariate Cox regressionTime of diagnosisTime of presentationMulti-modal therapyWorse OSClinical characteristicsMetastatic diseaseImproved survivalPediatric patientsDistant metastasisCox regressionRetrospective studyAnatomic distributionCancer DatabaseOsseous diseaseGender disparities in head and neck cancer chemotherapy clinical trials participation and treatment
Benchetrit L, Torabi SJ, Tate JP, Mehra S, Osborn HA, Young MR, Burtness B, Judson BL. Gender disparities in head and neck cancer chemotherapy clinical trials participation and treatment. Oral Oncology 2019, 94: 32-40. PMID: 31178210, DOI: 10.1016/j.oraloncology.2019.05.009.Peer-Reviewed Original ResearchConceptsChemotherapy clinical trialsNational Cancer DatabaseClinical trialsDefinitive radiotherapyChemotherapy administrationNational Comprehensive Cancer Network guidelinesMultivariable logistic regression analysisNeck squamous cell carcinomaEnd Results ProgramSquamous cell carcinomaClinical trial participationLogistic regression analysisGeneral U.S. populationChemotherapy useDefinitive chemoradiotherapyNCCN guidelinesAdult patientsDefinitive treatmentMultivariable analysisNetwork guidelinesResults ProgramCell carcinomaTrial participationCancer DatabaseU.S. patientsClinically node-negative head and neck mucosal melanoma: An analysis of current treatment guidelines & outcomes
Torabi SJ, Benchetrit L, Spock T, Cheraghlou S, Judson BL. Clinically node-negative head and neck mucosal melanoma: An analysis of current treatment guidelines & outcomes. Oral Oncology 2019, 92: 67-76. PMID: 31010627, DOI: 10.1016/j.oraloncology.2019.03.017.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCombined Modality TherapyDatabases, FactualDisease ManagementFemaleHead and Neck NeoplasmsHumansKaplan-Meier EstimateLymph NodesMaleMelanomaMiddle AgedMucous MembraneNeoplasm StagingPractice Guidelines as TopicPractice Patterns, Physicians'PrognosisProportional Hazards ModelsTreatment OutcomeYoung AdultConceptsElective neck dissectionMajority of patientsSinonasal cavityMM casesNCCN guidelinesNational Comprehensive Cancer Network guidelinesNeck mucosal melanomaNode-negative headNational Cancer DatabaseCurrent treatment guidelinesImproved OSRT utilizationSN patientsNCCN recommendationsNeck dissectionMM patientsMucosal melanomaTreatment guidelinesTreatment patternsNetwork guidelinesCancer DatabaseRetrospective analysisOral cavityPatientsSurvival rateNonsquamous cell laryngeal cancers: Incidence, demographics, care patterns, and effect of surgery
Torabi SJ, Cheraghlou S, Kasle DA, Savoca EL, Judson BL. Nonsquamous cell laryngeal cancers: Incidence, demographics, care patterns, and effect of surgery. The Laryngoscope 2019, 129: 2496-2505. PMID: 30632157, DOI: 10.1002/lary.27785.Peer-Reviewed Original ResearchConceptsEffect of surgeryNon-SCC patientsNeuroendocrine tumorsLaryngeal cancerClinical profileMinor salivary gland tumorsClinical M stageNon-SCC cohortSpecific surgical methodsNational Cancer DatabaseMajority of patientsMajor histological subtypesSalivary gland tumorsAdult patientsImproved survivalTreatment regimenDistant metastasisWorse prognosisHistological subtypesCancer DatabaseLaryngeal carcinomaSurgical methodsRetrospective analysisGland tumorsSurgery
2018
Survival Outcomes for Induction vs Adjuvant Chemotherapy in Squamous Cell Carcinoma of the Maxillary Sinus
Kuo P, Torabi SJ, Kraus D, Judson BL. Survival Outcomes for Induction vs Adjuvant Chemotherapy in Squamous Cell Carcinoma of the Maxillary Sinus. Otolaryngology 2018, 160: 658-663. PMID: 30296902, DOI: 10.1177/0194599818804777.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseAdjuvant chemotherapyMultivariate Cox regressionInduction chemotherapyLog-rank testMaxillary sinus cancerOverall survivalCox regressionSinus cancerMaxillary sinusUnivariate Kaplan-Meier analysisPoor local control ratesAdvanced maxillary sinus cancerAdjuvant chemotherapy cohortImproved overall survivalLocal control rateMortality hazard ratioKaplan-Meier analysisSquamous cell carcinomaSignificant mortality hazard ratiosSecondary database analysisWarrants further investigationPropensity-score matchingChemotherapy cohortHazard ratioAssociation of Facility and System Factors With Survival Among Pediatric Patients With Surgically Treated Head and Neck Sarcomas
Cheraghlou S, Li H, Judson BL. Association of Facility and System Factors With Survival Among Pediatric Patients With Surgically Treated Head and Neck Sarcomas. JAMA Otolaryngology - Head & Neck Surgery 2018, 144: 455-456. PMID: 29800240, PMCID: PMC6136052, DOI: 10.1001/jamaoto.2018.0183.Peer-Reviewed Original ResearchPediatric Salivary Cancer: Epidemiology, Treatment Trends, and Association of Treatment Modality with Survival
Morse E, Fujiwara RJT, Husain Z, Judson B, Mehra S. Pediatric Salivary Cancer: Epidemiology, Treatment Trends, and Association of Treatment Modality with Survival. Otolaryngology 2018, 159: 553-563. PMID: 29688836, DOI: 10.1177/0194599818771926.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBiopsy, NeedleCarcinoma, MucoepidermoidChemotherapy, AdjuvantChildChild, PreschoolCombined Modality TherapyCross-Sectional StudiesDatabases, FactualFemaleHumansImmunohistochemistryLogistic ModelsMaleMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingPrognosisProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesSalivary Gland NeoplasmsSurvival AnalysisTreatment OutcomeConceptsImproved overall survivalOverall survivalHigh tumor gradeTreatment modalitiesTumor gradeSalivary cancerAdjuvant radiationMultivariable Cox proportional hazards regressionNational Cancer Database 2004Cox proportional hazards regressionTreatment factorsPatients 19 yearsHigh-risk patientsSubset of patientsMultivariable logistic regressionProportional hazards regressionUS national databaseHigh-grade tumorsSalivary gland cancerAcinar cell carcinomaPediatric patientsTumor characteristicsHazards regressionCell carcinomaGland cancer
2017
Thirty‐day morbidity and mortality following otologic/neurotologic surgery: Analysis of the national surgical quality improvement program
Schwam ZG, Michaelides E, Kuo P, Hajek MA, Judson BL, Schutt C. Thirty‐day morbidity and mortality following otologic/neurotologic surgery: Analysis of the national surgical quality improvement program. The Laryngoscope 2017, 128: 1431-1437. PMID: 28940480, DOI: 10.1002/lary.26848.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramAdverse event ratesQuality Improvement ProgramPostoperative morbidityFunctional statusTumor resectionNeurotologic surgerySurgeons National Surgical Quality Improvement ProgramOpen woundsOverall adverse event rateEvent ratesHigher adverse event ratesThirty-day morbidityPoor functional statusRetrospective cohort studyOverall mortality rateMultivariable logistic regressionImpaired functional statusMastoid proceduresPostoperative mortalityMajor morbidityPostoperative complicationsSignificant comorbiditiesCohort studyComparing 30‐Day Morbidity and Mortality in Pediatric and Adult Otologic Surgery
Schwam ZG, Michaelides E, Schwam JR, Kuo P, Hajek MA, Judson BL, Schutt C. Comparing 30‐Day Morbidity and Mortality in Pediatric and Adult Otologic Surgery. Otolaryngology 2017, 157: 830-836. PMID: 28463634, DOI: 10.1177/0194599817704376.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramNSQIP PediatricAdverse eventsOtologic surgeryOverall adverse event rateMultivariable logistic regression analysisSurgical Quality Improvement ProgramMost adverse eventsPostoperative adverse eventsAdverse event ratesHigher readmission ratesLow complication rateMulti-institutional databaseLogistic regression analysisQuality Improvement ProgramPediatric otologic surgeryInfectious complicationsPostdischarge complicationsReadmission ratesComplication ratePediatric otolaryngologistsHigher oddsConcurrent proceduresAdult populationOtologic procedures
2016
Survival Outcomes for Combined Modality Therapy for Sinonasal Undifferentiated Carcinoma
Kuo P, Manes RP, Schwam ZG, Judson BL. Survival Outcomes for Combined Modality Therapy for Sinonasal Undifferentiated Carcinoma. Otolaryngology 2016, 156: 132-136. PMID: 27703092, DOI: 10.1177/0194599816670146.Peer-Reviewed Original ResearchConceptsSinonasal undifferentiated carcinomaCombined modality therapyNational Cancer DatabaseUndifferentiated carcinomaChemoradiotherapy groupModality therapyOverall survivalSurvival outcomesTreatment modalitiesCancer DatabaseSurvival rateAdjuvant chemotherapy groupImproved survival outcomesMultivariate Cox regressionCumulative survival rateKaplan-Meier analysisMulti-institutional studyCases of SNUCAdjuvant chemotherapyChemotherapy groupMultimodality therapyModality treatmentPrognostic factorsCox regressionAggressive malignancyProposing prognostic thresholds for lymph node yield in clinically lymph node‐negative and lymph node‐positive cancers of the oral cavity
Kuo P, Mehra S, Sosa JA, Roman SA, Husain ZA, Burtness BA, Tate JP, Yarbrough WG, Judson BL. Proposing prognostic thresholds for lymph node yield in clinically lymph node‐negative and lymph node‐positive cancers of the oral cavity. Cancer 2016, 122: 3624-3631. PMID: 27479645, DOI: 10.1002/cncr.30227.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseOral cavity cancerMortality hazard ratioLymph nodesHazard ratioNeck dissectionLymph node-negative cancersLymph node-positive cancersNode-positive cancersNode-positive cohortPositive lymph nodesTherapeutic neck dissectionEnd Results (SEER) databaseLymph node yieldHigh-volume centersExtensive neck dissectionMultiple cancer sitesNode-negative cancersOverall survivalHigher lymphPrognostic factorsTreatment guidelinesNode yieldResults databaseSurgical managementTreatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base
Kuo P, Sosa JA, Burtness BA, Husain ZA, Mehra S, Roman SA, Yarbrough WG, Judson BL. Treatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base. Cancer 2016, 122: 1853-1860. PMID: 27019213, DOI: 10.1002/cncr.29962.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCarcinoma, Squamous CellChemoradiotherapy, AdjuvantDatabases, FactualFemaleHead and Neck NeoplasmsHumansHypopharyngeal NeoplasmsKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsRadiotherapy, AdjuvantSquamous Cell Carcinoma of Head and NeckUnited StatesYoung AdultConceptsHypopharyngeal cancerDefinitive settingTreatment modalitiesSurvival rateNational Cancer Data BaseMultivariate Cox regression analysisKaplan-Meier survival curvesPrimary hypopharyngeal cancerUse of chemotherapyCox regression analysisDefinitive chemoradiotherapyAdjuvant chemoradiotherapyAdjuvant treatmentDefinitive radiotherapyAdult patientsOverall survivalClinical factorsDefinitive treatmentImproved survivalDistant metastasisSurvival outcomesChemoradiotherapyRadiotherapySurvival analysisSurvival curves
2015
Improved prognosis for patients with oral cavity squamous cell carcinoma: Analysis of the National Cancer Database 1998–2006
Schwam ZG, Judson BL. Improved prognosis for patients with oral cavity squamous cell carcinoma: Analysis of the National Cancer Database 1998–2006. Oral Oncology 2015, 52: 45-51. PMID: 26553389, DOI: 10.1016/j.oraloncology.2015.10.012.Peer-Reviewed Original ResearchConceptsOral cavity squamous cell carcinomaLate-stage diseaseThree-year overall survivalEarly-stage diseaseEarly-stage patientsStage diseaseSquamous cell carcinomaStage patientsNeck dissectionOverall survivalCell carcinomaObserved survival improvementNational Cancer DatabaseRetrospective cohort studyHigh-volume centersNegative surgical marginsAdvanced-stage patientsLarge administrative databaseAdjuvant chemoradiationOCSCC patientsAdjuvant therapyCohort studyImproved survivalSurgical marginsSurvival improvementRefusal of postoperative radiotherapy and its association with survival in head and neck cancer
Schwam ZG, Husain Z, Judson BL. Refusal of postoperative radiotherapy and its association with survival in head and neck cancer. Radiotherapy And Oncology 2015, 117: 343-350. PMID: 26508285, DOI: 10.1016/j.radonc.2015.10.013.Peer-Reviewed Original ResearchConceptsNeck cancer patientsPostoperative radiotherapyPredictive factorsCancer patientsOverall survivalNegative nodesThree-year overall survivalCox proportional hazards analysisNational Cancer DatabaseProportional hazards analysisLong-term outcomesMultivariable logistic regressionSlow disease progressionCharlson scorePathologic variablesImproved survivalKaplan-MeierNeck cancerCancer DatabaseDisease progressionRetrospective analysisMultivariate analysisPatientsLogistic regressionSelect headNational treatment patterns in patients presenting with Stage IVC head and neck cancer: analysis of the National Cancer Database
Schwam ZG, Burtness B, Yarbrough WG, Mehra S, Husain Z, Judson BL. National treatment patterns in patients presenting with Stage IVC head and neck cancer: analysis of the National Cancer Database. Cancer Medicine 2015, 4: 1828-1835. PMID: 26471244, PMCID: PMC5123708, DOI: 10.1002/cam4.546.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCombined Modality TherapyComorbidityDatabases, FactualFemaleHead and Neck NeoplasmsHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm MetastasisNeoplasm StagingPopulation SurveillanceRetrospective StudiesRisk FactorsTreatment OutcomeUnited StatesYoung AdultConceptsNational Cancer DatabaseSystemic therapyPalliative therapyTreatment patternsNeck cancerCancer DatabaseClinical trialsMedicaid/uninsured statusCox proportional hazards analysisCommon treatment regimenNational treatment patternsCharlson comorbidity scorePrimary disease siteRetrospective cohort analysisProportional hazards analysisRisk of deathNeck cancer patientsMedicare/Comorbidity scoreMetastatic headOverall survivalSystemic treatmentTreatment regimenDistant metastasisKaplan-MeierComplications and mortality following surgery for oral cavity cancer: Analysis of 408 cases
Schwam ZG, Sosa JA, Roman S, Judson BL. Complications and mortality following surgery for oral cavity cancer: Analysis of 408 cases. The Laryngoscope 2015, 125: 1869-1873. PMID: 26063059, DOI: 10.1002/lary.25328.Peer-Reviewed Original ResearchConceptsOral cavity cancerPostdischarge complicationsPostoperative complicationsNeck dissectionNational Surgical Quality Improvement Program Participant Use Data FilesSurgeons National Surgical Quality Improvement Program Participant Use Data FilesSurgical siteDay 14Oral cavity cancer surgeryParticipant Use Data FilePostdischarge surgical-site infectionsCommon adverse eventsRetrospective cohort studySurgical site complicationsHigh-risk patientsModifiable risk factorsSurgical site infectionDisease-specific complicationsMultivariate regression analysisRespiratory complicationsAdverse eventsCohort studyCurrent smokersSite complicationsCancer surgery
2014
Hypopharyngeal cancer incidence, treatment, and survival: Temporal trends in the United States
Kuo P, Chen MM, Decker RH, Yarbrough WG, Judson BL. Hypopharyngeal cancer incidence, treatment, and survival: Temporal trends in the United States. The Laryngoscope 2014, 124: 2064-2069. PMID: 25295351, DOI: 10.1002/lary.24651.Peer-Reviewed Original ResearchConceptsAverage annual percent changeHypopharyngeal cancerPatient demographicsTreatment modalitiesDisease severityEnd Results (SEER) databaseRetrospective cohort studyKaplan-Meier analysisAnnual percent changeAdult patientsCohort studyOverall survivalWorse survivalImproved survivalResults databaseT stageTumor characteristicsCox regressionCancer incidenceMultivariate analysisPercent changeLaryngopharyngectomyCancerIncidenceTemporal trends