2017
Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial
Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial. Clinical Therapeutics 2017, 39: 55-63. PMID: 28081848, PMCID: PMC10345862, DOI: 10.1016/j.clinthera.2016.12.002.Peer-Reviewed Original ResearchConceptsCoronary microvascular dysfunctionCoronary flow reserveCoronary artery diseaseChest painSymptomatic patientsArtery diseasePrimary outcomeEmergency departmentNonobstructive coronary artery diseaseRb-82 positron emission tomographyEffect of ranolazineRate-pressure productEmergency department patientsQTc-prolonging drugsRobust clinical trialsPositron emission tomographyHypertensive urgencyMicrovascular anginaMicrovascular dysfunctionUnderdiagnosed causeControlled TrialsDepartment patientsHeart failureAcute symptomsPressure product
2010
Depression as Modifiable Coronary Risk Factor in the Emergency Department Chest Pain Observation Unit
Safdar B, Foody JM, D'Onofrio G. Depression as Modifiable Coronary Risk Factor in the Emergency Department Chest Pain Observation Unit. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2010, 9: 82-87. PMID: 20520215, DOI: 10.1097/hpc.0b013e3181db06ef.Peer-Reviewed Original ResearchConceptsCoronary risk factorsModifiable coronary risk factorsRisk factorsUrban tertiary care hospital EDChest pain observation unitTertiary care hospital EDEmergency department observation unitFramingham risk scoreObservation unitProspective observational studyHealth service utilizationSeverity of depressionBehavioral health referralsCPC patientsChest painNonprivate insuranceED visitsStudy nursesCardiac symptomsHigher obesityHospital EDSpecialty referralsFuture trialsHealth referralsQuick Inventory