NMDA and non-NMDA receptors stimulation causes differential oxidative stress in rat cortical slices
Sanganahalli B, Joshi P, Joshi N. NMDA and non-NMDA receptors stimulation causes differential oxidative stress in rat cortical slices. Neurochemistry International 2006, 49: 475-480. PMID: 16860439, DOI: 10.1016/j.neuint.2006.03.006.Peer-Reviewed Original ResearchConceptsNon-NMDA receptorsAdult slicesReactive oxygen species formationNon-NMDAReactive oxygen speciesReceptor stimulationGlutamate receptorsNeuronal cell deathGlutamate-induced neuronal injuryGlutamate mediated neurotoxicityGlutamate receptor agonist NMDACell deathInflux of Ca(2+Mitochondrial depolarizationReceptor agonist NMDAFormation of reactive oxygen speciesNMDA receptor stimulationTreatment of slicesAge groupsAntagonist APVAgonist NMDAYoung slicesCortical slicesNMDA stimulationKA stimulation