Negative BOLD with Large Increases in Neuronal Activity
Schridde U, Khubchandani M, Motelow JE, Sanganahalli BG, Hyder F, Blumenfeld H. Negative BOLD with Large Increases in Neuronal Activity. Cerebral Cortex 2007, 18: 1814-1827. PMID: 18063563, PMCID: PMC2790390, DOI: 10.1093/cercor/bhm208.Peer-Reviewed Original ResearchConceptsCerebral blood flowCerebral blood volumeFunctional magnetic resonance imagingNegative BOLD signalsNeuronal activityBOLD signalLevel-dependent functional magnetic resonance imagingBlood oxygen level-dependent functional magnetic resonance imagingBOLD functional magnetic resonance imagingCerebral metabolic ratePositive BOLD signalMagnetic resonance imagingBlood flowNegative BOLDBlood volumeResonance imagingBrain regionsPathological conditionsNeuronal recordingsBrain activityFMRI signalsOxygen consumptionMetabolic rateMetabolic activitySeizures