2001
Ibuprofen as a Chemesthetic Stimulus: Evidence of a Novel Mechanism of Throat Irritation
Breslin P, Gingrich T, Green B. Ibuprofen as a Chemesthetic Stimulus: Evidence of a Novel Mechanism of Throat Irritation. Chemical Senses 2001, 26: 55-65. PMID: 11124216, DOI: 10.1093/chemse/26.1.55.Peer-Reviewed Original ResearchConceptsCapsaicin-sensitive receptorsThroat irritationRatings of irritationReceptor mechanismsSensory irritationNon-steroidal anti-inflammatory drug ibuprofenIrritationAnti-inflammatory drug ibuprofenOral irritantsThroatReceptorsNovel mechanismStimulationIbuprofenChemesthetic propertiesChemesthetic stimuliBuffering agentDrug ibuprofenPrickAgentsChemesthetic effects
1997
Perceived Irritation during Ingestion of Capsaicin or Piperine: Comparison of Trigeminal and Non-trigeminal Areas
Rentmeister-Bryant H, Green B. Perceived Irritation during Ingestion of Capsaicin or Piperine: Comparison of Trigeminal and Non-trigeminal Areas. Chemical Senses 1997, 22: 257-266. PMID: 9218138, DOI: 10.1093/chemse/22.3.257.Peer-Reviewed Original ResearchConceptsAnterior tongueIrritation ratingsIngestion of capsaicinRostro-caudal axisVagus nerveOral mucosaOropharyngeal regionPosterior tongueIntensity of sensationsChemical irritantsCapsaicinChemosensory irritationIrritationIngestionThroatIrritantsPiperineTongueChemesthetic stimuliResponsivenessPrevious findingsNerveTrigeminalMucosa