2000
Menthol desensitization of capsaicin irritation Evidence of a short-term anti-nociceptive effect
Green B, McAuliffe B. Menthol desensitization of capsaicin irritation Evidence of a short-term anti-nociceptive effect. Physiology & Behavior 2000, 68: 631-639. PMID: 10764892, DOI: 10.1016/s0031-9384(99)00221-8.Peer-Reviewed Original ResearchConceptsInterstimulus intervalFinal experimentPrevious researchSecond experimentCapsaicin stimuliCapsaicin-sensitive fibersAnti-nociceptive effectsStimuliSelfSecond exposureAntinociceptive effectTopical analgesicsSensory irritationCapsaicinPerceptionExposureDesensitizationCrossdesensitizationStimulationImplicationsMin
1998
Temporal characteristics of capsaicin desensitization and stimulus-induced recovery in the oral cavity
Green B, Rentmeister-Bryant H. Temporal characteristics of capsaicin desensitization and stimulus-induced recovery in the oral cavity. Physiology & Behavior 1998, 65: 141-149. PMID: 9811376, DOI: 10.1016/s0031-9384(98)00162-0.Peer-Reviewed Original ResearchConceptsCapsaicin desensitizationIntermittent stimulationMicroM capsaicinTopical analgesicsOral cavitySignificant desensitizationCapsaicinClinical useRecurrent stimulationDesensitizationStimulationBlock recoveryExposureMinutesRapid exposureTest stimuliStimuliTongueCandy formulationChemonociceptionAnalgesicsSecond testTreatment stimuliIrritation
1993
The sensory response to capsaicin during repeated topical exposures: differential effects on sensations of itching and pungency
Green B, Shaffer G. The sensory response to capsaicin during repeated topical exposures: differential effects on sensations of itching and pungency. Pain 1993, 53: 323-334. PMID: 8351161, DOI: 10.1016/0304-3959(93)90228-h.Peer-Reviewed Original ResearchConceptsInter-stimulus intervalTopical exposureIntensity of itchingUse of capsaicinApplication of capsaicinHand-held dynamometerDuration of sensitizationSensations of itchingTest 24 hFifth exposureDay 1Day 2Sensory irritationCapsaicinItchingOverall sensitivityDesensitizationLess sensitizationSensitizationSensory responsesMarked individual differencesTime courseDifferential effectsItchPungent sensationEvidence that removal of capsaicin accelerates desensitization on the tongue
Green B. Evidence that removal of capsaicin accelerates desensitization on the tongue. Neuroscience Letters 1993, 150: 44-48. PMID: 8469401, DOI: 10.1016/0304-3940(93)90104-s.Peer-Reviewed Original Research