2024
Association of Race and Ethnicity with Prescriptions for Continuous Glucose Monitoring Systems Among a National Sample of Veterans with Diabetes on Insulin Therapy
Lipska K, Oladele C, Zawack K, Gulanski B, Mutalik P, Reaven P, Lynch J, Lee K, Shih M, Lee J, Aslan M. Association of Race and Ethnicity with Prescriptions for Continuous Glucose Monitoring Systems Among a National Sample of Veterans with Diabetes on Insulin Therapy. Diabetes Technology & Therapeutics 2024 PMID: 39177775, DOI: 10.1089/dia.2024.0152.Peer-Reviewed Original ResearchVeterans with diabetesAssociation of raceCross-sectional analysis of dataU.S. Veterans Health AdministrationNational sample of veteransNational sampleInsulin therapyVeterans Health AdministrationSystem-level factorsSample of veteransNon-Hispanic patientsSelf-reported raceContinuous glucose monitoringCross-sectional analysisContinuous glucose monitoring useRate of prescriptionMultivariate mixed-effects modelAfrican American patientsLatino patientsHealth AdministrationAlaska NativesType 2 diabetesPercentage of patientsSignificant disparitiesMixed-effects models
2023
Metformin prescription for U.S. veterans with prediabetes, 2010–2019
Gulanski B, Goulet J, Radhakrishnan K, Ko J, Li Y, Rajeevan N, Lee K, Heberer K, Lynch J, Streja E, Mutalik P, Cheung K, Concato J, Shih M, Lee J, Aslan M. Metformin prescription for U.S. veterans with prediabetes, 2010–2019. Journal Of Investigative Medicine 2023, 72: 139-150. PMID: 37668313, DOI: 10.1177/10815589231201141.Peer-Reviewed Original ResearchConceptsBody mass indexVeterans Health AdministrationIncident prediabetesHigh riskHealth AdministrationRetrospective observational cohort studyType 2 diabetes mellitusUse of metforminObservational cohort studyProportion of veteransMetformin prescribingGestational diabetesCohort studyMetformin prescriptionDiabetes mellitusDiabetes preventionMass indexCardiovascular diseaseMultivariable modelPrediabetesSubset of individualsMetforminU.S. veteransHealthcare systemVeteransHigher burden of cardiometabolic and socioeconomic risk factors in women with type 2 diabetes: an analysis of the Glycemic Reduction Approaches in Diabetes (GRADE) baseline cohort
Gulanski B, Butera N, Krause-Steinrauf H, Lichtman J, Harindhanavudhi T, Green J, Suratt C, AbouAssi H, Desouza C, Ahmann A, Wexler D, Aroda V, Crandall J, McKee, Behringer-Massera S, Brown-Friday J, Xhori E, Ballentine-Cargill K, Duran S, Estrella H, de la torre S, Lukin J, Phillips L, Burgess E, Olson D, Rhee M, Wilson P, Raines T, Boers J, Costello J, Maher-Albertelli M, Mungara R, Savoye L, White C, Gullett C, Holloway L, Morehead F, Person S, Sibymon M, Tanukonda S, Adams C, Ross A, Balasubramanyam A, Gaba R, Hattery E, Ideozu A, Jimenez J, Montes G, Wright C, Hollander P, Roe E, Jackson A, Smiley A, Burt P, Estrada L, Chionh K, Ismail-Beigi F, Falck-Ytter C, Kassem L, Sood A, Tiktin M, Kulow T, Newman C, Stancil K, Cramer B, Iacoboni J, Kononets M, Sanders C, Tucker L, Werner A, Maxwell A, McPhee G, Patel C, Colosimo L, Krol A, Goland R, Pring J, Alfano L, Kringas P, Hausheer C, Tejada J, Gumpel K, Kirpitch A, Schneier H, Green J, AbouAssi H, Chatterjee R, Feinglos M, Jones J, Khan J, Zimmer R, Furst M, Satterwhite B, Thacker C, Kreider K, Mariash C, Mather K, Ismail H, Lteif A, Mullen M, Hamilton T, Patel N, Riera G, Jackson M, Pirics V, Aguillar D, Howard D, Hurt S, Bergenstal R, Carlson A, Martens T, Johnson M, Hill R, Hyatt J, Jensen C, Madden M, Martin D, Willis H, Konerza W, Yang S, Kleeberger K, Passi R, Fortmann S, Herson M, Mularski K, Glauber H, Prihoda J, Ash B, Carlson C, Ramey P, Schield E, Torgrimson-Ojerio B, Arnold K, Kauffman B, Panos E, Sahnow S, Bays K, Berame K, Cook J, Ghioni D, Gluth J, Schell K, Criscola J, Friason C, Jones S, Nazarov S, Barzilay J, Rassouli N, Puttnam R, Ojoawo B, Nelson R, Curtis M, Hollis B, Sanders-Jones C, Stokes K, El-Haqq Z, Kolli A, Tran T, Wexler D, Larkin M, Meigs J, Chambers B, Dushkin A, Rocchio G, Yepes M, Steiner B, Dulin H, Cayford M, Chu K, DeManbey A, Hillard M, Martin K, Thangthaeng N, Gurry L, Kochis R, Raymond E, Ripley V, Stevens C, Park J, Aroda V, Ghazi A, Magee M, Ressing A, Loveland A, Hamm M, Hurtado M, Kuhn A, Leger J, Manandhar L, Mwicigi F, Sanchez O, Young T, Garg R, Lagari-Libhaber V, Florez H, Valencia, Marks J, Casula S, Oropesa-Gonzalez L, Hue L, Cuadot A, Nieto-Martinez R, Veliz A, Gutt M, Kendal Y, Veciana B, Ahmann A, Aby-Daniel D, Joarder F, Morimoto V, Sprague C, Yamashita D, Cady N, Rivera-Eschright N, Kirchhoff P, Gomez B, Adducci J, Goncharova A, Hox S, Petrovitch H, Matwichyna M, Jenkins V, Broadwater L, Ishii R, Bermudez N, Hsia D, Cefalu W, Greenway F, Waguespack C, King E, Fry G, Dragg A, Gildersleeve B, Arceneaux J, Haynes N, Thomassie A, Pavlionis M, Bourgeois B, Hazlett C, Mudaliar S, Henry R, Boeder S, Pettus J, Diaz E, Garcia-Acosta D, Maggs S, DeLue C, Stallings A, Castro E, Hernandez S, Krakoff J, Curtis J, Killean T, Khalid M, Joshevama E, Diaz E, Martin D, Tsingine K, Karshner T, Albu J, Pi-Sunyer F, Frances S, Maggio C, Ellis E, Bastawrose J, Gong X, Banerji M, August P, Lee M, Lorber D, Brown N, Josephson D, Thomas L, Tsovian M, Cherian A, Jacobson M, Mishko M, Kirkman, Buse J, Dostou J, Machineni S, Young L, Bergamo K, Goley A, Kerr J, Largay J, Guarda S, Cuffee J, Culmer D, Fraser R, Almeida H, Coffer S, Debnam E, Kiker L, Morton S, Josey K, Fuller G, Garvey W, Cherrington A, Dyer D, Lawson M, Griffith O, Agne A, McCullars S, Cohen R, Craig J, Rogge M, Burton K, Kersey K, Wilson C, Lipp S, Meulen M, Adkins C, Onadeko T, Rasouli N, Baker C, Schroeder E, Razzaghi M, Lyon C, Penaloza R, Underkofler C, Lorch R, Douglass S, Steiner S, Sivitz W, Cline E, Knosp L, McConnell J, Lowe T, Herman W, Pop-Busui R, Tan M, Martin C, Waltje A, Katona A, Goodhall L, Eggleston R, Kuo S, Bojescu S, Bule S, Kessler N, LaSalle E, Whitley K, Seaquist E, Bantle A, Harindhanavudhi T, Kumar A, Redmon B, Bantle J, Coe M, Mech M, Taddese A, Lesne L, Smith S, Desouza C, Kuechenmeister L, Shivaswamy V, Burbach S, Rodriguez, Seipel K, Alfred A, Morales A, Eggert J, Lord G, Taylor W, Tillson R, Schade D, Adolphe A, Burge M, Duran-Valdez E, Martinez J, Bancroft A, Kunkel S, Ahmad F, McGinnis D, Pucchetti B, Scripsick E, Zamorano A, DeFronzo R, Cersosimo E, Abdul-Ghani M, Triplitt C, Juarez D, Garza R, Verastiqui H, Wright K, Puckett C, Raskin P, Rhee C, Abraham S, Jordan L, Sao S, Morton L, Smith O, Walker L, Schnurr-Breen L, Ayala R, Kreymer R, Sturgess D, Utzschneider K, Kahn, Wright L, Boyko E, Tsai E, Trence D, Trikudanathan S, Fattaleh B, Montgomery B, Atkinson K, Kozedub A, Concepcion T, Moak C, Prikhodko N, Rhothisen S, Elasy T, Martin S, Shackelford L, Goidel R, Hinkle N, Lovell C, Myers J, Hogan J, McGill J, Salam M, Schweiger T, Kissel S, Recklein C, Clifton M, Tamborlane W, Camp A, Gulanski B, Inzucchi, Pham K, Alguard M, Gatcomb P, Lessard K, Perez M, Iannone L, Montosa A, Magenheimer E, Cefalu W, Fradkin J, Burch H, Bremer A, Nathan D, Lachin J, Krause-Steinrauf H, Younes N, Bebu I, Butera N, Buys C, Fagan A, Gao Y, Ghosh A, Gramzinski, Hall S, Kazemi E, Legowski E, Liu H, Suratt C, Tripputi M, Arey A, Backman M, Bethepu J, Lund C, Dhaliwal P, McGee P, Mesimer E, Ngo L, Steffes M, Seegmiller J, Saenger A, Arends V, Gabrielson D, Conner T, Warren S, Day J, Huminik J, Scrymgeour A, Soliman E, Pokharel Y, Zhang Z, Campbell C, Hu J, Keasler L, Hensley S, Li Y, Mihalcea R, Min D, Perez-Rosas V, Prosser L, Resnicow K, Ye W, Shao H, Zhang P, Luchsinger J, Sanchez D, Assuras S, Groessl E, Sakha F, Chong H, Hillery N, Everett B, Abdouch I, Bahtiyar G, Brantley P, Broyles F, Canaris G, Copeland P, Craine J, Fein W, Gliwa A, Hope L, Lee, Meiners R, Meiners V, O’Neal H, Park J, Sacerdote A, Sledge E, Soni L, Steppel-Reznik J, Turchin A, Brooks-Worrell B, Hampe C, Palmer J, Shojaie A, Higgins J, Fischer L, Golden S, Gonzalez J, Naik A, Walker E, Lotenberg L, Gallivan J, Lim J, Tuncer D. Higher burden of cardiometabolic and socioeconomic risk factors in women with type 2 diabetes: an analysis of the Glycemic Reduction Approaches in Diabetes (GRADE) baseline cohort. BMJ Open Diabetes Research & Care 2023, 11: e003159. PMID: 37094945, PMCID: PMC10151943, DOI: 10.1136/bmjdrc-2022-003159.Peer-Reviewed Original ResearchConceptsBody mass indexRisk factorsSocioeconomic risk factorsCardiovascular diseaseGreater prevalenceContemporary cohortHigher mean body mass indexMean body mass indexType 2 diabetes mellitusBurden of CVDYoung womenBlood pressure targetsGlycemia Reduction ApproachesAngiotensin receptor blockersCardiometabolic risk factorsLow HDL cholesterolPowerful risk factorComparative effectiveness studiesGreater relative riskCross-sectional analysisMetformin monotherapyTarget LDLReceptor blockersPressure targetsSevere obesityPerformance of a modified fracture risk assessment tool for fragility fracture prediction among older veterans living with HIV
Womack J, Murphy T, Leo-Summers L, Kidwai-Khan F, Skanderson M, Gill T, Gulanski B, Rodriguez-Barradas M, Tien P, Yin M, Hsieh E. Performance of a modified fracture risk assessment tool for fragility fracture prediction among older veterans living with HIV. AIDS 2023, 37: 1399-1407. PMID: 37070536, PMCID: PMC10329997, DOI: 10.1097/qad.0000000000003566.Peer-Reviewed Original ResearchConceptsFracture Risk Assessment ToolMajor osteoporotic fractureRisk assessment toolCohort studyHip fractureOsteoporotic fracturesVeterans Aging Cohort StudyAging Cohort StudyMultivariable logistic regressionType of fractureRace/ethnicityAssessment toolGlucocorticoid useHIV cohortFragility fracturesPrevious fractureRheumatoid arthritisSmoking statusFracture riskModest discriminationOlder veteransLogistic regressionOccurrence of fracturesHIVAlcohol usePersonalized Digital Health Information to Substantiate Human-Delivered Exercise Support for Adults With Type 1 Diabetes
Ash G, Nally L, Stults-Kolehmainen M, De Los Santos M, Jeon S, Brandt C, Gulanski B, Spanakis E, Baker J, Weinzimer S, Fucito L. Personalized Digital Health Information to Substantiate Human-Delivered Exercise Support for Adults With Type 1 Diabetes. Clinical Journal Of Sport Medicine 2023, 33: 512-520. PMID: 36715983, PMCID: PMC10898917, DOI: 10.1097/jsm.0000000000001078.Peer-Reviewed Original ResearchConceptsContinuous glucose monitoringExercise supportHealth informationDigital health informationBody mass indexType 1 diabetesCommunity-based sampleSevere hypoglycemiaMass indexPsychosocial assessmentCGM useHigh satisfaction ratingsPhysician oversightType 1Future interventionsGlucose monitoringMedical readinessMolecular biomarkersBaseline observationsInterventionSatisfaction ratingsAdultsExerciseBehavioral skillsSingle group
2022
Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes.
GRADE Study Research Group, Nathan DM, Lachin JM, Balasubramanyam A, Burch HB, Buse JB, Butera NM, Cohen RM, Crandall JP, Kahn SE, Krause-Steinrauf H, Larkin ME, Rasouli N, Tiktin M, Wexler DJ, Younes N. Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes. N Engl J Med 2022, 387: 1063-1074. PMID: 36129996, DOI: 10.1056/NEJMoa2200433.Peer-Reviewed Original ResearchGlycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes.
GRADE Study Research Group, Nathan DM, Lachin JM, Bebu I, Burch HB, Buse JB, Cherrington AL, Fortmann SP, Green JB, Kahn SE, Kirkman MS, Krause-Steinrauf H, Larkin ME, Phillips LS, Pop-Busui R, Steffes M, Tiktin M, Tripputi M, Wexler DJ, Younes N. Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes. N Engl J Med 2022, 387: 1075-1088. PMID: 36129997, DOI: 10.1056/NEJMoa2200436.Peer-Reviewed Original ResearchA Population-Level Analysis of the Protective Effects of Androgen Deprivation Therapy Against COVID-19 Disease Incidence and Severity
Lee KM, Heberer K, Gao A, Becker DJ, Loeb S, Makarov DV, Gulanski B, DuVall SL, Aslan M, Lee J, Shih MC, Lynch JA, Hauger RL, Rettig M. A Population-Level Analysis of the Protective Effects of Androgen Deprivation Therapy Against COVID-19 Disease Incidence and Severity. Frontiers In Medicine 2022, 9: 774773. PMID: 35602518, PMCID: PMC9115469, DOI: 10.3389/fmed.2022.774773.Peer-Reviewed Original ResearchAndrogen deprivation therapyCOVID-19 outcomesSARS-CoV-2ADT patientsDeprivation therapyCancer patientsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testingMale veteransSevere COVID-19 outcomesMultivariable logistic regression modelingSARS-CoV-2 infectionSevere COVID-19 illnessCOVID-19 pathophysiologyCOVID-19 patientsCOVID-19 illnessCOVID-19 severityVeterans Health AdministrationCoronavirus disease-19Logistic regression analysisLogistic regression modelingCOVID-19COVID-19 incidenceMale patientsCOVID-19 disease incidenceDisease-19
2021
Association of Glycemia, Lipids, and Blood Pressure With Cognitive Performance in People With Type 2 Diabetes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Luchsinger J, Younes N, Manly J, Barzilay J, Valencia W, Larkin M, Falck-Ytter C, Krause-Steinrauf H, Pop-Busui R, Florez H, Seaquist E, Crandall J, McKee M, Brown-Friday J, Xhori E, Ballentine-Cargill K, Duran S, Lukin J, Beringher S, Gonzalez de la torre S, Phillips L, Burgess E, Olson D, Rhee M, Wilson P, Raines T, Costello J, Gullett C, Maher-Albertelli M, Morehead F, Mungara R, Person S, Savoye L, Sibymon M, Tanukonda S, White C, Holloway L, Adams C, Ross A, Balasubramanyam A, Gonzalez E, Wright C, Hollander P, Roe E, Uy A, Burt P, Estrada L, Chionh K, Ismail-Beigi F, Falck-Ytter C, Sayyed Kassem L, Sood A, Tiktin M, Cramer B, Iacoboni J, Kononets M, Kulow T, Newman C, Stancil K, Sanders C, Tucker L, Werner A, Krol A, McPhee G, Patel C, Colosimo L, Goland R, Pring J, Kringas P, Tejada J, Hausheer C, Schneier H, Gumpel K, Kirpitch A, Green J, AbouAssi H, Chatterjee R, Feinglos M, English Jones J, Khan S, Kimpel J, Zimmer R, Furst M, Satterwhite B, Thacker C, Evans Kreider K, Mather K, Lteif A, Hamilton T, Patel N, Riera G, Jackson M, Pirics V, Howard D, Aguillar D, Hurt S, Bergenstal R, Carlson A, Martens T, Johnson M, Hill R, Hyatt J, Jensen C, Madden M, Martin D, Willis H, Konerza W, Passi R, Kleeberger K, Fortmann S, Herson M, Mularski K, Glauber H, Prihoda J, Ash B, Carlson C, Ramey P, Schield E, Torgrimson-Ojerio B, Arnold K, Kauffman B, Panos E, Sahnow S, Bays K, Cook J, Gluth J, Sasaki D, Schell K, Criscola J, Friason C, Jones S, Nazarov S, Barzilay J, Rassouli N, Puttnam R, Curtis M, Stokes K, Hollis B, Sanders-Jones C, Nelson R, El-Haqq Z, Kolli A, Tran T, Wexler D, Larkin M, Meigs J, Dushkin A, Rocchio G, Chambers B, Yepes M, Steiner B, Dulin H, Cayford M, DeManbey A, Gurry L, Hillard M, Martin K, Stevens C, Thangthaeng N, Kochis R, Raymond E, Ripley V, Park J, Aroda V, Ghazi A, Loveland A, Hurtado M, Kuhn A, Mofor F, Florez H, Valencia W, Marks J, Oropesa-Gonzalez L, Riccio Veliz A, Nieto-Martinez R, Gutt M, Ahmann A, Aby-Daniel D, Joarder F, Morimoto V, Sprague C, Yamashita D, Cady N, Kirchhoff P, Rivera- Eschright N, Adducci J, Morales Gomez B, Goncharova A, Hox S, Petrovitch H, Matwichyna M, Jenkins V, Bermudez N, Ishii R, Hsia D, Cefalu W, Greenway F, Waguespack C, King E, Haynes N, Thomassie A, Bourgeois B, Hazlett C, Henry R, Mudaliar S, Boeder S, Pettus J, Diaz E, DeLue C, Castro E, Hernandez S, Krakoff J, Curtis J, Killean T, Joshevama E, Diaz E, Martin D, Karshner T, Albu J, Pi-Sunyer F, Frances S, Maggio C, Ellis E, Bastawrose J, Gong X, Banerji M, August P, Lorber D, Brown N, Josephson D, Thomas L, Tsovian M, Cherian A, Jacobson M, Mishko M, Kirkman M, Bergamo K, Buse J, Dostou J, Young L, Goley A, Kerr J, Largay J, Guarda S, Cuffee J, Culmer D, Fraser R, Almeida H, Coffer S, Debnam E, Kiker L, Morton S, Josey K, Fuller G, Garvey W, Cherrington A, Golson D, Griffith O, Robertson M, Agne A, McCullars S, Cohen R, Craig J, Kersey K, Rogge M, Wilson C, Burton K, Lipp S, Vonder Meulen M, Rasouli N, Schroeder E, Steiner S, Baker C, Underkofler C, Douglass S, Sivitz W, Cline E, Knosp L, McConnell J, Lowe T, Herman W, Pop-Busui R, Tan M, Martin C, Waltje A, Goodhall L, Eggleston R, Kuo S, Bule S, Kessler N, LaSalle E, Seaquist E, Bantle A, Kumar A, Redmon B, Bantle J, Harindhanavudhi T, Coe M, Mech M, Taddese A, Lesne L, Smith S, Desouza C, Kuechenmeister L, Shivaswamy V, Morales A, Rodriguez M, Seipel K, Alfred A, Eggert J, Lord G, Taylor W, Tillson R, Schade D, Adolphe A, Burge M, Duran-Valdez E, Martinez J, Hernandez McGinnis D, Pucchetti B, Scripsick E, DeFronzo R, Cersosimo E, Abdul-Ghani M, Triplitt C, Verastiqui H, Garza R, Wright K, Puckett C, Raskin P, Rhee C, Abraham S, Jordan L, Sao S, Morton L, Smith O, Osornio Walker L, Schnurr-Breen L, Ayala R, Kraymer R, Sturgess D, Utzschneider K, Kahn S, Alarcon-Casas Wright L, Boyko E, Tsai E, Trence D, Fattaleh B, Montgomery B, Atkinson K, Concepcion T, Kozedub A, Moak C, Rhothisen S, Elasy T, Martin S, Shackelford L, Goidel R, Hinkle N, Lipps Hogan J, Lovell C, Myers J, McGill J, Salam M, Kissel S, Schweiger T, Recklein Carol Tamborlane W, Gatcomb P, Camp A, Gulanski B, Inzucchi S, Pham K, Alguard M, Lessard K, Perez M, Magenheimer E, Montoza A, Nathan D, Lachin J, Buse J, Kahn S, Krause-Steinrauf H, Larkin M, Tiktin M, Wexler D, Burch H, Linder B, Bremer A, Younes N, Backman M, Bebu I, Buys C, Fagan Murphy A, Gao Y, Gramzinski M, Hall S, Legowski E, Arey A, Bethepu J, Lund C, Mangat Dhaliwal P, McGee P, Mesimer E, Ngo L, Steffes M, Seegmiller J, Saenger A, Arends V, Gabrielson D, Conner T, Warren S, Day J, Scrymgeour A, Soliman E, Zhang Z, Campbell C, Hu J, Keasler L, Hensley S, Li Y, Herman W, Martin C, Waltje A, Kuo S, Mihalcea R, Perez-Rosas V, Prosser L, Resnicow K, Ye W, Shao H, Zhang P, Luchsinger J, Sanchez D, Burch H, Bremer A, Linder B, Fradkin J, Groessl E, Chong H, Hillery N, Abdouch I, Brantley P, Broyles F, Canaris G, Copeland P, Craine J, Fein W, Lee M, Meiners R, Meiners V, O’Neal H, Park J, Sledge E, Steppel-Resnick J, Turchin A, Brooks-Worrell B, Hampe C, Newgard C, Palmer J, Shojaie A, Higgins J, Fischer L, Golden S, Gonzalez J, Naik A, Walker E, Doner Lotenberg L, Gallivan J, Lim J, Tuncer D, Behringer-Massera S. Association of Glycemia, Lipids, and Blood Pressure With Cognitive Performance in People With Type 2 Diabetes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes Care 2021, 44: 2286-2292. PMID: 34285097, PMCID: PMC8740937, DOI: 10.2337/dc20-2858.Peer-Reviewed Original ResearchConceptsType 2 diabetesGlycemia Reduction ApproachesDigit Symbol Substitution TestBlood pressureStatin useComparative effectiveness studiesHypertension historyAssociation of glycemiaSystolic BPDiastolic BPEffectiveness studiesRelation of glycemiaMean diabetes durationDiastolic blood pressureSystolic blood pressureAnimal Fluency TestCross-sectional analysisSpanish English Verbal Learning TestDiabetes durationExecutive cognitive functionHigh LDLSBP levelsVerbal Learning TestLower LDLMean ageEvaluation of Web-Based and In-Person Methods to Recruit Adults With Type 1 Diabetes for a Mobile Exercise Intervention: Prospective Observational Study
Ash GI, Griggs S, Nally LM, Stults-Kolehmainen M, Jeon S, Brandt C, Gulanski BI, Spanakis EK, Baker JS, Whittemore R, Weinzimer SA, Fucito LM. Evaluation of Web-Based and In-Person Methods to Recruit Adults With Type 1 Diabetes for a Mobile Exercise Intervention: Prospective Observational Study. JMIR Diabetes 2021, 6: e28309. PMID: 34047700, PMCID: PMC8299346, DOI: 10.2196/28309.Peer-Reviewed Original ResearchType 1 diabetesEligible volunteersExercise interventionClinical trialsIncremental costProspective observational studyGreater New HavenCharacteristics of enrolleesHigh-risk participantsOlder patientsOverall cohortPatients 18Clinical visitsUncommon conditionAdults 18Observational studySnowball samplingActive adultsT1DEligibility screeningPrior trialsLower click ratesPatientsActive individualsEligibility rates
2020
Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort.
Rasouli N, Younes N, Utzschneider KM, Inzucchi SE, Balasubramanyam A, Cherrington AL, Ismail-Beigi F, Cohen RM, Olson DE, DeFronzo RA, Herman WH, Lachin JM, Kahn SE, Crandall J, McKee M, Brown-Friday J, Xhori E, Ballentine-Cargill K, Duran S, Lukin J, Beringher S, de la torre S, Phillips L, Burgess E, Olson D, Rhee M, Wilson P, Raines T, Costello J, Gullett C, Maher-Albertelli M, Morehead F, Mungara R, Person S, Savoye L, Sibymon M, Tanukonda S, Ann White C, Holloway L, Adams C, Ross A, Balasubramanyam A, Gonzalez E, Wright C, Hollander P, Roe E, Uy A, Burt P, Estrada L, Chionh K, Ismail-Beigi F, Falck-Ytter C, Kassem L, Sood A, Tiktin M, Cramer B, Iacoboni J, Kononets M, Kulow T, Newman C, Stancil K, Sanders C, Tucker L, Werner A, Krol A, McPhee G, Patel C, Colosimo L, Goland R, Pring J, Kringas P, Tejada J, Hausheer C, Schneier H, Gumpel K, Kirpitch A, Green J, AbouAssi H, Chatterjee R, Feinglos M, Jones J, Khan S, Kimpel J, Zimmer R, Furst M, Satterwhite B, Thacker C, Kreider K, Mather K, Lteif A, Hamilton T, Patel N, Riera G, Jackson M, Pirics V, Howard D, Aguillar D, Hurt S, Bergenstal R, Carlson A, Martens T, Johnson M, Hill R, Hyatt J, Jensen C, Madden M, Martin D, Willis H, Konerza W, Passi R, Kleeberger K, Fortmann S, Herson M, Mularski K, Glauber H, Prihoda J, Ash B, Carlson C, Ramey P, Schield E, Torgrimson-Ojerio B, Arnold K, Kauffman B, Panos E, Sahnow S, Bays K, Cook J, Gluth J, Sasaki D, Schell K, Criscola J, Friason C, Jones S, Nazarov S, Barzilay J, Rassouli N, Puttnam R, Curtis M, Stokes K, Hollis B, Sanders-Jones C, Nelson R, El-Haqq Z, Kolli A, Tran T, Wexler D, Larkin M, Meigs J, Dushkin A, Rocchio G, Chambers B, Yepes M, Steiner B, Dulin H, Cayford M, DeManbey A, Gurry L, Hillard M, Martin K, Stevens C, Thangthaeng N, Kochis R, Raymond E, Ripley V, Park J, Aroda V, Ghazi A, Loveland A, Hurtado M, Kuhn A, Mofor F, Florez H, Valencia W, Marks J, Oropesa-Gonzalez L, Riccio Veliz A, Nieto-Martinez R, Gutt M, Ahmann A, Aby-Daniel D, Joarder F, Morimoto V, Sprague C, Yamashita D, Cady N, Kirchhoff P, Rivera-Eschright N, Adducci J, Gomez B, Goncharova A, Hox S, Petrovitch H, Matwichyna M, Jenkins V, Bermudez N, Ishii R, Hsia D, Cefalu W, Greenway F, Waguespack C, King E, Haynes N, Thomassie A, Bourgeois B, Hazlett C, Henry R, Mudaliar S, Boeder S, Pettus J, Diaz E, DeLue C, Castro E, Hernandez S, Krakoff J, Curtis J, Killean T, Joshevama E, Diaz E, Martin D, Karshner T, Albu J, Pi-Sunyer F, Frances S, Maggio C, Ellis E, Bastawrose J, Gong X, Banerji M, August P, Lorber D, Brown N, Josephson D, Thomas L, Tsovian M, Cherian A, Jacobson M, Mishko M, Kirkman M, Bergamo K, Buse J, Dostou J, Young L, Goley A, Kerr J, Largay J, Guarda S, Cuffee J, Culmer D, Fraser R, Almeida H, Coffer S, Debnam E, Kiker L, Morton S, Garvey K, Fuller G, Garvey W, Cherrington A, Golson D, Griffith O, Catherine M, Agne A, McCullars S, Cohen R, Craig J, Kersey K, Rogge M, Wilson C, Burton K, Lipp S, Mary Beth V, Rasouli N, Schroeder E, Steiner S, Baker C, Underkofler C, Douglass S, Sivitz W, Cline E, Knosp L, McConnell J, Lowe T, Herman W, Pop-Busui R, Tan M, Martin C, Waltje A, Goodhall L, Eggleston R, Kuo S, Bule S, Kessler N, LaSalle E, Seaquist E, Bantle A, Kumar A, Redmon B, Bantle J, Harindhanavudhi T, Coe M, Mech M, Taddese A, Lesne L, Smitha S, Desouz C, Kuechenmeister L, Shivaswamy V, Morales A, Rodriguez M, Seipel K, Alfred A, Eggert J, Lord G, Taylor W, Tillson R, Schade D, Adolphe A, Burge M, Duran-Valdez E, Martinez J, Hernandez McGinnis D, Pucchetti B, Scripsick E, DeFronzo R, Cersosimo E, Abdul-Ghani M, Triplitt C, Verastiqui H, Garza R, Wright K, Puckett C, Raskin P, Rhee C, Abraham S, Jordan L, Sao S, Morton L, Smith O, Osornio Walker L, Schnurr-Breen L, Ayala R, Kraymer R, Sturgess D, Utzschneider K, Kahn S, Alarcon-Casas Wright L, Boyko E, Tsai E, Trence D, Fattaleh B, Montgomery B, Atkinson K, Concepcion T, Kozedub A, Moak C, Rhothisen S, Elasy T, Martin S, Shackelford L, Goidel R, Hinkle N, Lipps Hogan J, Lovell C, Myers J, McGill J, Salam M, Kissel S, Schweiger T, Recklein C, Tamborlane W, Gatcomb P, Camp A, Gulanski B, Inzucchi S, Pham K, Alguard M, Lessard K, Perez M, Magenheimer E, Montoza A, Nathan D, Nathan D, Lachin J, Buse J, Kahn S, Krause-Steinrauf H, Larkin M, Tiktin M, Wexler D, Burch H, Linder B, Bremer A, Lachin J, Krause-Steinrauf H, Younes N, Backman M, Bebu I, Buys C, Fagan Murphy A, Gao Y, Gramzinski M, Hall S, Legowski E, Arey A, Bethepu J, Lund C, Mangat Dhaliwal P, McGee P, Mesimer E, Ngo L, Steffes M, Seegmiller J, Saenger A, Arends V, Gabrielson D, Conner T, Warren S, Day J, Scrymgeour A, Soliman E, Zhang Z, Campbell C, Hu J, Keasler L, Hensley S, Li Y, Herman W, Martin C, Waltje A, Kuo S, Mihalcea R, Perez-Rosas V, Prosser L, Resnicow K, Ye W, Shao H, Zhang P, Luchsinger J, Sanchez D, Burch H, Bremer A, Linder B, Fradkin J, Groessl E, Chong H, Hillery N, Abdouch I, Brantley P, Broyles F, Canaris G, Copeland P, Craine J, Fein W, Lee M, Meiners R, Meiners V, O’Neal H, Park J, Sledge E, Steppel-Resnick J, Turchin A, Brooks-Worrell B, Hampe C, Newgard C, Palmer J, Shojaie A, Higgins J, Fischer L, Golden S, Gonzalez J, Naik A, Walker E, Doner Lotenberg L, Gallivan J, Lim J, Tuncer D, Behringer-Massera S. Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort. Diabetes Care 2020, 44: 340-349. PMID: 33334808, PMCID: PMC7818323, DOI: 10.2337/dc20-1787.Peer-Reviewed Original ResearchConceptsΒ-cell functionTG/HDLBlack/African AmericanAmerican Indians/Alaska NativesDisposition indexInsulin sensitivityHigher HbAOral glucose tolerance testAfrican AmericansGlycemia Reduction ApproachesHigher disposition indexHDL cholesterol ratioAlaska NativesGlucose tolerance testOral disposition indexC-peptide indexSimilar insulin sensitivityType 2 diabetesYears of ageCross-sectional analysisBMI 34.2Metformin monotherapyBaseline characteristicsInsulinogenic indexLower HbAMedicare Prescription Drug Plan Coverage of Hormone Therapies Used by Transgender Individuals
Solotke MT, Liu P, Dhruva SS, Gulanski B, Shah ND, Ross JS. Medicare Prescription Drug Plan Coverage of Hormone Therapies Used by Transgender Individuals. LGBT Health 2020, 7: 137-145. PMID: 32267818, DOI: 10.1089/lgbt.2019.0306.Peer-Reviewed Original ResearchOptimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight
Sivitz W, Phillips L, Wexler D, Fortmann S, Camp A, Tiktin M, Perez M, Craig J, Hollander P, Cherrington A, Aroda V, Tan M, Krakoff J, Rasouli N, Butera N, Younes N, Crandall J, Diane McKee M, Brown-Friday J, Xhori E, Ballentine-Cargill K, Duran S, Lukin J, Beringher S, Gonzalez de la torre S, Phillips L, Burgess E, Olson D, Rhee M, Wilson P, Stephanie Raines T, Costello J, Gullett C, Maher-Albertelli M, Morehead F, Mungara R, Person S, Savoye L, Sibymon M, Tanukonda S, Ann White C, Holloway L, Adams C, Ross A, Balasubramanyam A, Gonzalez E, Wright C, Hollander P, Roe E, Uy A, Burt P, Estrada L, Chionh K, Ismail-Beigi F, Falck-Ytter C, Sayyed Kassem L, Sood A, Tiktin M, Cramer B, Iacoboni J, Kononets M, Kulow T, Newman C, Stancil K, Sanders C, Tucker L, Werner A, Krol A, McPhee G, Patel C, Colosimo L, Goland R, Pring J, Kringas P, Tejada J, Hausheer C, Schneier H, Gumpel K, Kirpitch A, Green J, AbouAssi H, Chatterjee R, Feinglos M, English Jones J, Khan S, Kimpel J, Zimmer R, Furst M, Satterwhite B, Thacker C, Evans Kreider K, Mather K, Lteif A, Hamilton T, Patel N, Riera G, Jackson M, Pirics V, Howard D, Aguillar D, Hurt S, Bergenstal R, Carlson A, Martens T, Johnson M, Hill R, Hyatt J, Jensen C, Madden M, Martin D, Willis H, Konerza W, Passi R, Kleeberger K, Fortmann S, Herson M, Mularski K, Glauber H, Prihoda J, Ash B, Carlson C, Anne Ramey P, Schield E, Torgrimson-Ojerio B, Arnold K, Kauffman B, Panos E, Sahnow S, Bays K, Cook J, Gluth J, Sasaki D, Schell K, Criscola J, Friason C, Jones S, Nazarov S, Barzilay J, Rassouli N, Puttnam R, Curtis M, Stokes K, Hollis B, Sanders-Jones C, Nelson R, El-Haqq Z, Kolli A, Tran T, Wexler D, Mary L, Meigs J, Dushkin A, Rocchio G, Chambers B, Yepes M, Steiner B, Dulin H, Cayford M, DeManbey A, Gurry L, Hillard M, Martin K, Stevens C, Thangthaeng N, Kochis R, Raymond E, Ripley V, Park J, Aroda V, Ghazi A, Loveland A, Hurtado M, Kuhn A, Mofor F, Florez H, Valencia W, Marks J, Oropesa-Gonzalez L, Riccio Veliz A, Nieto-Martinez R, Gutt M, Ahmann A, Aby-Daniel D, Joarder F, Morimoto V, Sprague C, Yamashita D, Cady N, Kirchhoff P, Rivera-Eschright N, Adducci J, Gomez B, Goncharova A, Hox S, Petrovitch H, Matwichyna M, Jenkins V, Bermudez N, Ishii R, Hsia D, Cefalu W, Greenway F, Waguespack C, King E, Haynes N, Thomassie A, Bourgeois B, Hazlett C, Henry R, Mudaliar S, Boeder S, Pettus J, Diaz E, DeLue C, Castro E, Hernandez S, Krakoff J, Curtis J, Killean T, Joshevama E, Diaz E, Martin D, Karshner T, Albu J, Pi-Sunyer F, Frances S, Maggio C, Ellis E, Bastawrose J, Gong X, Ann Banerji M, August P, Lorber D, Brown N, Josephson D, Thomas L, Tsovian M, Cherian A, Jacobson M, Mishko M, Kirkman M, Bergamo K, Buse J, Dostou J, Young L, Goley A, Kerr J, Largay J, Guarda S, Cuffee J, Culmer D, Fraser R, Almeida H, Coffer S, Debnam E, Kiker L, Morton S, Josey K, Fuller G, Garvey W, Cherrington A, Golson D, Griffith O, Catherine Robertson M, Agne A, McCullars S, Cohen R, Craig J, Kersey K, Rogge M, Wilson C, Burton K, Lipp S, Vonder Meulen M, Rasouli N, Schroeder E, Steiner S, Baker C, Underkofler C, Douglass S, Sivitz W, Cline E, Knosp L, McConnell J, Lowe T, Herman W, Pop-Busui R, Tan M, Martin C, Waltje A, Goodhall L, Eggleston R, Kuo S, Bule S, Kessler N, LaSalle E, Seaquist E, Bantle A, Kumar A, Redmon B, Bantle J, Harindhanavudhi T, Coe M, Mech M, Taddese A, Lesne L, Smith S, Desouza C, Kuechenmeister L, Shivaswamy V, Laura Morales A, Rodriguez M, Seipel K, Alfred A, Eggert J, Lord G, Taylor W, Tillson R, Schade D, Adolphe A, Burge M, Duran-Valdez E, Martinez J, McGinnis D, Pucchetti B, Scripsick E, DeFronzo R, Cersosimo E, Abdul-Ghani M, Triplitt C, Verastiqui H, Irene Garza R, Wright K, Puckett C, Raskin P, Rhee C, Abraham S, Fan Jordan L, Sao S, Morton L, Smith O, Osornio Walker L, Schnurr-Breen L, Ayala R, Brian Kraymer R, Sturgess D, Utzschneider K, Kahn S, Alarcon-Casas Wright L, Boyko E, Tsai E, Trence D, Fattaleh B, Montgomery B, Atkinson K, Concepcion T, Kozedub A, Moak C, Rhothisen S, Elasy T, Martin S, Shackelford L, Goidel R, Hinkle N, Lipps Hogan J, Lovell C, Myers J, McGill J, Salam M, Kissel S, Schweiger T, Recklein C, Tamborlane W, Gatcomb P, Camp A, Gulanski B, Inzucchi S, Pham K, Alguard M, Lessard K, Perez M, Magenheimer E, Montoza A, Nathan D, Lachin J, Buse J, Kahn S, Krause-Steinrauf H, Larkin M, Tiktin M, Wexler D, Burch H, Linder B, Bremer A, Lachin J, Krause-Steinrauf H, Younes N, Backman M, Bebu I, Buys C, Fagan Murphy A, Gao Y, Gramzinski M, Hall S, Legowski E, Arey A, Bethepu J, Lund C, Mangat Dhaliwal P, McGee P, Mesimer E, Ngo L, Steffes M, Seegmiller J, Saenger A, Arends V, Gabrielson D, Conner T, Warren S, Day J, Scrymgeour A, Soliman E, Zhang Z, Campbell C, Hu J, Keasler L, Hensley S, Li Y, Herman W, Martin C, Waltje A, Kuo S, Mihalcea R, Perez-Rosas V, Prosser L, Resnicow K, Ye W, Shao H, Zhang P, Luchsinger J, Sanchez D, Burch H, Bremer A, Linder B, Fradkin J, Groessl E, Chong H, Hillery N, Abdouch I, Brantley P, Broyles F, Canaris G, Copeland P, Craine J, Fein W, Lee M, Meiners R, Meiners V, O’Neal H, Park J, Sledge E, Steppel-Resnick J, Turchin A, Brooks-Worrell B, Hampe C, Newgard C, Palmer J, Shojaie A, Higgins J, Fischer L, Golden S, Gonzalez J, Naik A, Walker E, Doner Lotenberg L, Gallivan J, Lim J, Tuncer D, Behringer-Massera S. Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight. Diabetes Care 2020, 43: 940-947. PMID: 32139384, PMCID: PMC7171946, DOI: 10.2337/dc19-1769.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBlood GlucoseBody WeightCalibrationComparative Effectiveness ResearchDiabetes Mellitus, Type 2Dose-Response Relationship, DrugDrug Therapy, CombinationFemaleGlycated HemoglobinHumansHypoglycemic AgentsInsulinLiraglutideMaleMaximum Tolerated DoseMetforminMiddle AgedSitagliptin PhosphateSulfonylurea CompoundsWeight LossConceptsType 2 diabetesLow doseBody weightGlycemia Reduction ApproachesGlucose-lowering drugsSuboptimal glycemic controlExercise counselingMetformin therapyPrespecified analysisGlycemic controlPrimary outcomeMedication adherenceHigher HbASD changeDiabetesMetforminGlycemiaDoseWeight lossHbAGreater reductionDaysParticipantsGrade cohorts
2019
Compromised endothelial function in transgender men taking testosterone
Gulanski BI, Flannery CA, Peter PR, Leone CA, Stachenfeld NS. Compromised endothelial function in transgender men taking testosterone. Clinical Endocrinology 2019, 92: 138-144. PMID: 31765022, PMCID: PMC6957681, DOI: 10.1111/cen.14132.Peer-Reviewed Original ResearchConceptsEndothelial functionTransgender menEndothelial dysfunctionCisgender femalesClinical cardiovascular riskCardiovascular risk factorsImpaired endothelial functionEarly follicular phaseAndrogen excessCardiovascular riskVasodilatory responseCoronary arteryHormonal milieuFollicular phaseTestosterone treatmentMenstrual cycleRisk factorsFemale genderAtherosclerotic plaquesEarly signsTestosteroneTotal TSImportant markerDysfunctionMenRationale and Design for a GRADE Substudy of Continuous Glucose Monitoring
Larkin M, Nathan D, Bebu I, Krause-Steinrauf H, Herman W, Higgins J, Tiktin M, Cohen R, Lund C, Bergenstal R, Johnson M, Arends V, Crandall J, McKee M, Brown-Friday J, Xhori E, Ballentine-Cargill K, Duran S, Lukin J, Beringher S, de la torre S, Phillips L, Burgess E, Olson D, Rhee M, Wilson P, Raines T, Costello J, Gullett C, Maher-Albertelli M, Morehead F, Mungara R, Person S, Savoye L, Sibymon M, Tanukonda S, White C, Holloway L, Adams C, Ross A, Balasubramanyam A, Gonzalez E, Wright C, Hollander P, Roe E, Uy A, Burt P, Estrada L, Chionh K, Ismail-Beigi F, Falck-Ytter C, Kassem L, Sood A, Cramer B, Iacoboni J, Kononets M, Kulow T, Newman C, Stancil K, Sanders C, Tucker L, Werner A, Krol A, McPhee G, Patel C, Colosimo L, Goland R, Pring J, Kringas P, Tejada J, Hausheer C, Schneier H, Gumpel K, Kirpitch A, Green J, AbouAssi H, Chatterjee R, Feinglos M, Jones J, Khan S, Kimpel J, Zimmer R, Furst M, Satterwhite B, Thacker C, Kreider K, Mather K, Lteif A, Hamilton T, Patel N, Riera G, Jackson M, Pirics V, Howard D, Aguillar D, Hurt S, Bergenstal R, Carlson A, Martens T, Johnson M, Hill R, Hyatt J, Jensen C, Madden M, Martin D, Willis H, Konerza W, Passi R, Kleeberger K, Fortmann S, Herson M, Mularski K, Glauber H, Prihoda J, Ash B, Carlson C, Ramey P, Schield E, Torgrimson-Ojerio B, Arnold K, Kauffman B, Panos E, Sahnow S, Bays K, Cook J, Gluth J, Sasaki D, Schell K, Criscola J, Friason C, Jones S, Nazarov S, Barzilay J, Rassouli N, Puttnam R, Curtis M, Stokes K, Hollis B, Sanders-Jones C, Nelson R, El-Haqq Z, Kolli A, Tran T, Wexler D, Meigs J, Dushkin A, Rocchio G, Chambers B, Yepes M, Steiner B, Dulin H, Cayford M, DeManbey A, Gurry L, Hillard M, Martin K, Stevens C, Thangthaeng N, Kochis R, Raymond E, Ripley V, Park J, Aroda V, Ghazi A, Loveland A, Hurtado M, Kuhn A, Mofor F, Florez H, Valencia W, Marks J, Oropesa-Gonzalez L, Riccio Veliz A, Nieto-Martinez R, Gutt M, Ahmann A, Aby-Daniel D, Joarder F, Morimoto V, Sprague C, Yamashita D, Cady N, Kirchhoff P, Rivera-Eschright N, Adducci J, Gomez B, Goncharova A, Hox S, Petrovitch H, Matwichyna M, Jenkins V, Bermudez N, Ishii R, Hsia D, Cefalu W, Greenway F, Waguespack C, King E, Haynes N, Thomassie A, Bourgeois B, Hazlett C, Henry R, Mudaliar S, Boeder S, Pettus J, Diaz E, DeLue C, Castro E, Hernandez S, Krakoff J, Curtis J, Killean T, Joshevama E, Diaz E, Martin D, Karshner T, Albu J, Pi-Sunyer F, Frances S, Maggio C, Ellis E, Bastawrose J, Gong X, Banerji M, August P, Lorber D, Brown N, Josephson D, Thomas L, Tsovian M, Cherian A, Jacobson M, Mishko M, Kirkman M, Bergamo K, Buse J, Dostou J, Young L, Goley A, Kerr J, Largay J, Guarda S, Cuffee J, Culmer D, Fraser R, Almeida H, Coffer S, Debnam E, Kiker L, Morton S, Josey K, Fuller G, Garvey W, Cherrington A, Golson D, Griffith O, Robertson M, Agne A, McCullars S, Craig J, Kersey K, Rogge M, Wilson C, Burton K, Lipp S, Meulen M, Rasouli N, Schroeder E, Steiner S, Baker C, Underkofler C, Douglass S, Sivitz W, Cline E, Knosp L, McConnell J, Lowe T, Pop-Busui R, Tan M, Martin C, Waltje A, Goodhall L, Eggleston R, Kuo S, Bule S, Kessler N, LaSalle E, Seaquist E, Bantle A, Kumar A, Redmon B, Bantle J, Harindhanavudhi T, Coe M, Mech M, Taddese A, Lesne L, Smith S, Desouza C, Kuechenmeister L, Shivaswamy V, Morales A, Rodriguez M, Seipel K, Alfred A, Eggert J, Lord G, Taylor W, Tillson R, Schade D, Adolphe A, Burge M, Duran-Valdez E, Martinez J, McGinnis D, Pucchetti B, Scripsick E, DeFronzo R, Cersosimo E, Abdul-Ghani M, Triplitt C, Verastiqui H, Garza R, Wright K, Puckett C, Raskin P, Rhee C, Abraham S, Jordan L, Sao S, Morton L, Smith O, Walker L, Schnurr-Breen L, Ayala R, Kraymer R, Sturgess D, Utzschneider K, Kahn S, Wright L, Boyko E, Tsai E, Trence D, Fattaleh B, Montgomery B, Atkinson K, Concepcion T, Kozedub A, Moak C, Rhothisen S, Elasy T, Martin S, Shackelford L, Goidel R, Hinkle N, Hogan J, Lovell C, Myers J, McGill J, Salam M, Kissel S, Schweiger T, Recklein C, Tamborlane W, Gatcomb P, Camp A, Gulanski B, Inzucchi S, Pham K, Alguard M, Lessard K, Perez M, Magenheimer E, Montoza A, Burch H, Bremer A, Linder B, Fradkin J, Lachin J, Kahn S, Burch H, Younes N, Backman M, Buys C, Murphy A, Gao Y, Gramzinski M, Hall S, Legowski E, Arey A, Bethepu J, Dhaliwal P, McGee P, Mesimer E, Ngo L, Steffes M, Seegmiller J, Saenger A, Gabrielson D, Conner T, Warren S, Day J, Scrymgeour A, Soliman E, Zhang Z, Campbell C, Hu J, Keasler L, Hensley S, Li Y, Herman W, Mihalcea R, Perez-Rosas V, Prosser L, Resnicow K, Ye W, Shao H, Zhang P, Luchsinger J, Sanchez D, Groessl E, Chong H, Hillery N, Abdouch I, Brantley P, Broyles F, Canaris G, Copeland P, Craine J, Fein W, Lee M, Meiners R, Meiners V, O'Neal H, Park J, Sledge E, Steppel-Resnick J, Turchin A, Higgins J. Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring. Diabetes Technology & Therapeutics 2019, 21: 682-690. PMID: 31393176, PMCID: PMC7207016, DOI: 10.1089/dia.2019.0202.Peer-Reviewed Original ResearchConceptsDiabetes medicationsAverage glucoseOral glucose tolerance testRed blood cell turnoverGlucose tolerance testNon-Hispanic African AmericansType 2 diabetesDuration of hypoglycemiaNon-Hispanic whitesPotential clinical implicationsContinuous glucose monitoringGlycemic profileGlucose variabilityTolerance testAnnual visitsStudy groupClinical careTreatment groupsSubstudyClinical implicationsStudy participantsHispanic whitesMedicationsGlucose monitoringInterindividual variationFacilitators and barriers to successful recruitment into a large comparative effectiveness trial: a qualitative study.
Behringer-Massera S, Browne T, George G, Duran S, Cherrington A, McKee MD, GRADE Research Group. Facilitators and barriers to successful recruitment into a large comparative effectiveness trial: a qualitative study. J Comp Eff Res 2019, 8: 815-826. PMID: 31368793, DOI: 10.2217/cer-2019-0010.Peer-Reviewed Original Research1141-P: Detailed Phenotype of Randomized Participants by Age in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE)
ARODA V, KRAUSE-STEINRAUF H, BUSE J, GULANSKI B, FLOREZ H, AHMANN A, LOVELAND A, KUHN A, LONIER J, MATHER K, WEXLER D. 1141-P: Detailed Phenotype of Randomized Participants by Age in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes 2019, 68 DOI: 10.2337/db19-1141-p.Peer-Reviewed Original ResearchNovo Nordisk A/SMannKind CorporationBaseline characteristicsKidney diseaseSpouse/partnerInclusion criteriaClinical phenotypeAge groupsGlycemia Reduction ApproachesComparative effectiveness studiesDistinct clinical phenotypesNational InstituteEli LillyAdvisory PanelEisai Inc.More CVDProminent hyperglycemiaSecond medicationAdvancing Translational SciencesDiabetic dyslipidemiaMore medicationsPrevalent comorbiditiesRandomized participantsAge-related differencesRandomized treatmentCompromised endothelial function in transgender men taking testosterone
Stachenfeld N, Leone C, Gulanski B. Compromised endothelial function in transgender men taking testosterone. The FASEB Journal 2019, 33: 696.4-696.4. DOI: 10.1096/fasebj.2019.33.1_supplement.696.4.Peer-Reviewed Original ResearchEndothelial functionEndothelial dysfunctionBlood pressureTransgender menRisk factorsCisgender femalesCardiovascular risk factorsEarly follicular phaseSystolic blood pressureFull-text articlesTestosterone therapyAndrogen excessCardiovascular riskVasodilatory responseBlood lipidsHDL cholesterolSystolic BPLDL cholesterolCoronary arteryHormonal milieuFollicular phaseAndrogen treatmentMenstrual cycleCardiovascular diseaseAtherosclerotic plaques
2013
Increased Brain Transport and Metabolism of Acetate in Hypoglycemia Unawareness
Gulanski BI, De Feyter HM, Page KA, Belfort-DeAguiar R, Mason GF, Rothman DL, Sherwin RS. Increased Brain Transport and Metabolism of Acetate in Hypoglycemia Unawareness. The Journal Of Clinical Endocrinology & Metabolism 2013, 98: 3811-3820. PMID: 23796565, PMCID: PMC4425818, DOI: 10.1210/jc.2013-1701.Peer-Reviewed Original ResearchConceptsHypoglycemia-associated autonomic failureHypoglycemia unawarenessT1DM individualsEpinephrine levelsBrain transportControl groupType 1 diabetes mellitusDefective glucose counterregulationHealthy nondiabetic controlsSevere hypoglycemia unawarenessIntensive insulin therapyLong-term complicationsHospital research unitEntire study populationT1DM participantsAutonomic failureGlucose counterregulationInsulin therapyDiabetes mellitusNondiabetic controlsCerebral cortexAcute hypoglycemiaT1DM controlsCerebral energeticsStudy populationIncreased brain uptake and oxidation of acetate in heavy drinkers
Jiang L, Gulanski BI, De Feyter HM, Weinzimer SA, Pittman B, Guidone E, Koretski J, Harman S, Petrakis IL, Krystal JH, Mason GF. Increased brain uptake and oxidation of acetate in heavy drinkers. Journal Of Clinical Investigation 2013, 123: 1605-1614. PMID: 23478412, PMCID: PMC3613911, DOI: 10.1172/jci65153.Peer-Reviewed Original ResearchConceptsHeavy drinkersBrain uptakeN-acetylaspartateLight drinkersChronic heavy drinkingNew therapeutic approachesGreater brain uptakeAlcohol detoxificationConsequences of drinkingTherapeutic approachesMagnetic resonance spectroscopyMore brainHeavy drinkingDrinkersBrainWeeksBloodDrinksGlutamateDrinkingResonance spectroscopy