2013
Aurora kinases in head and neck cancer
Mehra R, Serebriiskii IG, Burtness B, Astsaturov I, Golemis EA. Aurora kinases in head and neck cancer. The Lancet Oncology 2013, 14: e425-e435. PMID: 23993387, PMCID: PMC4139969, DOI: 10.1016/s1470-2045(13)70128-1.Peer-Reviewed Original ResearchConceptsAurora kinase AAurora kinasesKinase AExpression inhibits cell growthSquamous cell carcinomaHigh-throughput datasetsSmall molecule inhibitorsInhibits cell growthAurora kinase inhibitorsGenomic instabilityHealthy cellsBiological functionsKinaseCell growthCancer cellsEarly phase trialsKinase inhibitorsOverexpressionCellsDrug combination trialsNeck cancerCombination trialsPhase trialsSmall studyCarcinoma
2004
Improved method for the detection of cytokeratin 19-positive cells in the peripheral blood of breast cancer patients
Alvero AB, Burtness BA, Ercan AG, Sapi E. Improved method for the detection of cytokeratin 19-positive cells in the peripheral blood of breast cancer patients. Laboratory Investigation 2004, 84: 658-661. PMID: 15105816, DOI: 10.1038/labinvest.3700086.Peer-Reviewed Original ResearchConceptsBreast cancer patientsQuantitative real-time reverse transcription-polymerase chain reactionCancer patientsDisease-free survivalReal-time reverse transcription-polymerase chain reactionReverse transcription-polymerase chain reactionDetection of cytokeratinClinical parametersPeripheral bloodPolymerase chain reactionCytokeratin 19PatientsTumor cellsChain reactionImproved assayAssaysCellsTherapyCytokeratinBlood