2023
Role of homeobox d10 gene targeted signaling pathways in cancers
Surendran H, Palaniyandi T, Natarajan S, Hari R, Viwanathan S, Baskar G, Abdul Wahab M, Ravi M, Rajendran B. Role of homeobox d10 gene targeted signaling pathways in cancers. Pathology - Research And Practice 2023, 248: 154643. PMID: 37406379, DOI: 10.1016/j.prp.2023.154643.Peer-Reviewed Original ResearchConceptsTranscription factorsHomeobox gene familyHomeotic transcription factorsGene expression changesTumor suppressor geneD10 geneGene familyHomeobox genesCancer signalingOrgan developmentTissue homeostasisGene expressionExpression changesSignaling pathwaysCell differentiationSuppressor geneFunctional interactionGenesHOXD10 geneCancer treatment targetHOXD10Pathway dysregulationTherapeutic resistancePathwayMolecule action
2017
comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis
Rajendran B, Deng C. comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis. Oncotarget 2017, 5: 102263-102276. PMID: 29254242, PMCID: PMC5731952, DOI: 10.18632/oncotarget.20404.Peer-Reviewed Original ResearchCopy number alterationsBreast tumorigenesisNumber alterationsGenetic network analysisPrognostic molecular signaturesCancer-associated genesCellular functionsOBSCN geneMultifunctional proteinBreast cancer progressionMyofibril organizationClinical breast cancer samplesGene expressionIntegrative analysisFunctional mutationsDownstream pathwaysExpression dataGenesCell adhesionMolecular signaturesCancer progressionGene methylationDirect roleTumorigenesisObscurin