2022
Quantitative Models of Lipid Transfer and Membrane Contact Formation
Zhang Y, Ge J, Bian X, Kumar A. Quantitative Models of Lipid Transfer and Membrane Contact Formation. Contact 2022, 5: 25152564221096024. PMID: 36120532, PMCID: PMC9481209, DOI: 10.1177/25152564221096024.Peer-Reviewed Original ResearchMembrane contact sitesLipid transfer proteinLipid transferMembrane tensionMCS formationLipid exchange mechanismsMembrane contact formationOrganelle biogenesisExtended synaptotagminsOrganelle dynamicsMembrane proteinsDifferent organellesMembrane bindingMembrane expansionContact sitesMolecular mechanismsLipid flowLipid homeostasisTransfer proteinSimple lipidsProteinMembraneDistinct compositionLipidsKey role
2021
Single-molecule manipulation of macromolecules on GUV or SUV membranes using optical tweezers
Wang Y, Kumar A, Jin H, Zhang Y. Single-molecule manipulation of macromolecules on GUV or SUV membranes using optical tweezers. Biophysical Journal 2021, 120: 5454-5465. PMID: 34813728, PMCID: PMC8715244, DOI: 10.1016/j.bpj.2021.11.2884.Peer-Reviewed Original ResearchConceptsOptical tweezersOptical trappingSingle-molecule manipulation studiesMembrane protein dynamicsMembrane proteinsSingle-molecule manipulationMembrane tensionTweezersHigh membrane tensionProtein conformational changesModel membranesMembrane bindingProtein dynamicsC2AB domainConformational changesManipulation studiesSUV membranesReversible foldingSmall unilamellar vesiclesGUVsTrappingDNA hairpinsUnilamellar vesiclesProteinMembrane