2024
Positron Emission Tomography in the Diagnosis and Management of Cardiac Allograft Vasculopathy
Csecs I, Yakkali S, Feher A. Positron Emission Tomography in the Diagnosis and Management of Cardiac Allograft Vasculopathy. Current Cardiovascular Imaging Reports 2024, 17: 85-92. DOI: 10.1007/s12410-024-09595-7.Peer-Reviewed Original ResearchManagement of CAVPositron emission tomography myocardial perfusion imagingCardiac allograft vasculopathyInvasive coronary angiographyMyocardial perfusion imagingMyocardial flow reservePositron emission tomographyHeart transplant recipientsMyocardial blood flowAllograft vasculopathyTransplant recipientsPET-derived MBFInternational Society for Heart and Lung Transplantation guidelinesCAV detectionAlternative to invasive coronary angiographyEfficacy of positron emission tomographyRoutine surveillance protocolEmission tomographyClass IIa indicationFrequent invasive proceduresReduce radiation exposurePositron emission tomography imagingPrognostic valueCoronary angiographyMulticenter study
2023
The fat and the flow: multiparametric imaging assessment of pericoronary adipose tissue and myocardial blood flow
Csecs I, Feher A. The fat and the flow: multiparametric imaging assessment of pericoronary adipose tissue and myocardial blood flow. Journal Of Nuclear Cardiology 2023, 30: 1570-1573. PMID: 36929294, DOI: 10.1007/s12350-023-03247-x.Peer-Reviewed Original Research
2022
PET Myocardial Blood Flow for Post-transplant Surveillance and Cardiac Allograft Vasculopathy in Heart Transplant Recipients
Feher A, Miller EJ. PET Myocardial Blood Flow for Post-transplant Surveillance and Cardiac Allograft Vasculopathy in Heart Transplant Recipients. Current Cardiology Reports 2022, 24: 1865-1871. PMID: 36279035, DOI: 10.1007/s11886-022-01804-3.Peer-Reviewed Original ResearchConceptsHeart transplant recipientsAllograft vasculopathyTransplant recipientsPositron emission tomography myocardial perfusionOverall graft survivalPost-transplant surveillanceCardiac allograft vasculopathyHeart transplant patientsTomography myocardial perfusionRecent FindingsMultiple studiesMyocardial perfusion imagingMyocardial blood flowMBF quantificationGraft survivalHeart transplantationTransplant patientsTransplant rejectionSerial monitoringPrognostic performancePET myocardial blood flowBlood flowMyocardial perfusionPerfusion imagingMBF assessmentBlood flow quantification
2019
Application of Hybrid Matrix Metalloproteinase-Targeted and Dynamic 201Tl Single-Photon Emission Computed Tomography/Computed Tomography Imaging for Evaluation of Early Post-Myocardial Infarction Remodeling
Thorn SL, Barlow SC, Feher A, Stacy MR, Doviak H, Jacobs J, Zellars K, Renaud JM, Klein R, deKemp RA, Khakoo AY, Lee T, Spinale FG, Sinusas AJ. Application of Hybrid Matrix Metalloproteinase-Targeted and Dynamic 201Tl Single-Photon Emission Computed Tomography/Computed Tomography Imaging for Evaluation of Early Post-Myocardial Infarction Remodeling. Circulation Cardiovascular Imaging 2019, 12: e009055. PMID: 31707811, PMCID: PMC7250243, DOI: 10.1161/circimaging.119.009055.Peer-Reviewed Original ResearchConceptsMyocardial blood flowSingle photon emissionBlood flowRecombinant TIMP-3Matrix metalloproteinasesR injuryTomography/Intracoronary deliveryMMP activationPost-myocardial infarction remodelingSubsequent left ventricular remodelingHybrid single-photon emissionDual-isotope single-photon emissionTomography/Computed Tomography ImagingLeft ventricular remodelingIschemia/reperfusionPost-MI remodelingPost-myocardial infarctionComputed tomography (CT) imagingIntracoronary infusionVentricular functionSaline groupVentricular remodelingNoninvasive evaluationTreatment groups
2017
Quantitative Assessment of Coronary Microvascular Function
Feher A, Sinusas AJ. Quantitative Assessment of Coronary Microvascular Function. Circulation Cardiovascular Imaging 2017, 10: e006427. PMID: 28794138, PMCID: PMC5678979, DOI: 10.1161/circimaging.117.006427.Peer-Reviewed Original ResearchMeSH KeywordsComputed Tomography AngiographyCoronary AngiographyCoronary CirculationEchocardiographyHeart DiseasesHumansMagnetic Resonance ImagingMicrocirculationMyocardial Perfusion ImagingPositron-Emission TomographyPredictive Value of TestsPrognosisReproducibility of ResultsTomography, Emission-Computed, Single-PhotonConceptsCoronary microvascular dysfunctionMyocardial blood flowMicrovascular dysfunctionBlood flowMyocardial perfusionCoronary microvascular impairmentCoronary microvascular functionEpicardial coronary arteriesNormal myocardial perfusionMyocardial contrast echocardiographyAbsolute myocardial blood flowImportant prognostic relevanceMagnetic resonance imagingPositron emission tomographySingle photon emissionMicrovascular impairmentMicrovascular functionMultiple imaging modalitiesPrognostic relevanceCoronary arteryCoronary flowCoronary perfusionContrast echocardiographyClinical valueFunctional microcirculation