2022
Meta-Analysis Comparing Drug-Coated Balloons and Percutaneous Transluminal Angioplasty for Infrapopliteal Artery Disease
Barbarawi M, Qazi A, Lee J, Barbarawi O, Al-Abdouh A, Mhanna M, Vashist A. Meta-Analysis Comparing Drug-Coated Balloons and Percutaneous Transluminal Angioplasty for Infrapopliteal Artery Disease. The American Journal Of Cardiology 2022, 183: 115-121. PMID: 36116953, DOI: 10.1016/j.amjcard.2022.08.007.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal balloon angioplastyDrug-coated balloonsConventional percutaneous transluminal balloon angioplastyMajor target limb amputationTarget limb amputationTarget lesion revascularizationCritical limb ischemiaInfrapopliteal arterial diseaseArterial diseaseLesion revascularizationCause mortalityLimb ischemiaArtery diseaseLimb amputationEfficacy of DCBUse of DCBInfrapopliteal peripheral arterial diseaseMajor adverse cardiovascular eventsEnd pointInfrapopliteal artery diseaseAdverse cardiovascular eventsPrimary end pointSecondary end pointsPeripheral arterial diseaseTransluminal balloon angioplasty
2020
NOAC-Based Sual Therapy Versus Warfarin-Based Triple Therapy After Percutaneous Coronary Intervention or Acute Coronary Syndrome in Patients With Atrial Fibrillation: A Systematic Review and Meta-Analysis
Dahal K, Mosleh W, Almnajam M, Khaddr M, Adeel M, Vashist A, Robinson P, Azrin M, Lee J. NOAC-Based Sual Therapy Versus Warfarin-Based Triple Therapy After Percutaneous Coronary Intervention or Acute Coronary Syndrome in Patients With Atrial Fibrillation: A Systematic Review and Meta-Analysis. Cardiovascular Revascularization Medicine 2020, 21: 1202-1208. PMID: 32173329, DOI: 10.1016/j.carrev.2020.03.012.Peer-Reviewed Original ResearchConceptsAcute coronary syndromePercutaneous coronary interventionRandomized clinical trialsDual therapyTriple therapyStent thrombosisAtrial fibrillationCoronary syndromeCoronary interventionSystematic reviewRelevant non-major bleedingRisk of STComposite of mortalityConcomitant atrial fibrillationEfficacy of NOACsMajor efficacy outcomeNon-major bleedingTIMI minor bleedingDual antiplatelet therapyPrimary safety outcomeBleeding outcomesCRNM bleedingIschemic outcomesISTH majorP2Y12 agents
2016
Innovation in Data Abstraction, Education, and Consistent Application of Best Practice Guidelines: Experience and Real-World Results from a University Hospital in a Cost-Centric Environment.
Lakireddy P, Canning P, Lee J, Azrin M, Vashist A. Innovation in Data Abstraction, Education, and Consistent Application of Best Practice Guidelines: Experience and Real-World Results from a University Hospital in a Cost-Centric Environment. Connecticut Medicine 2016, 80: 97-103. PMID: 27024981.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeCardiac CatheterizationConnecticutCost ControlCost-Benefit AnalysisData CollectionDatabases, FactualDecision MakingDelivery of Health CareEmergency Medical ServicesGuideline AdherenceHospitals, UniversityHumansMyocardial InfarctionOutcome and Process Assessment, Health CarePatient Care TeamPractice Guidelines as TopicQuality of Health CareConceptsEmergency medical servicesPractice guidelinesBest practice guidelinesCardiac catheterization laboratory activationAcute coronary syndromeCatheterization laboratory activationCore measuresTask Force recommendationsCoronary syndromeLowest tertilePrehospital activationUniversity HospitalLaboratory activationPatient outcomesEMS roleExpeditious revascularizationMedical servicesHospitalDecision pathwaysCareTask ForceGuidelinesSignificant improvementData abstractionActivation
2014
Molecular imaging of plaque vulnerability
Tavakoli S, Vashist A, Sadeghi MM. Molecular imaging of plaque vulnerability. Journal Of Nuclear Cardiology 2014, 21: 1112-1128. PMID: 25124827, PMCID: PMC4229449, DOI: 10.1007/s12350-014-9959-4.Peer-Reviewed Original Research
2008
Noninvasive Detection of Risk for Emotion Provoked Myocardial Ischemia
Burg MM, Graeber B, Vashist A, Collins D, Earley C, Liu J, Lampert R, Soufer R. Noninvasive Detection of Risk for Emotion Provoked Myocardial Ischemia. Psychosomatic Medicine 2008, 71: 14-20. PMID: 18941131, PMCID: PMC2739989, DOI: 10.1097/psy.0b013e318187c035.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngerAngiotensin-Converting Enzyme InhibitorsBlood PressureCoronary DiseaseEpinephrineFemaleHeart RateHumansImagery, PsychotherapyMaleManometryMiddle AgedMyocardial IschemiaNorepinephrinePlethysmographyPredictive Value of TestsPulsatile FlowRiskSensitivity and SpecificityStress, PsychologicalTomography, Emission-Computed, Single-PhotonVascular ResistanceConceptsPeripheral arterial tonometryCoronary artery diseasePAT ratioMyocardial ischemiaMajor adverse cardiac eventsStable coronary artery diseaseLower PAT ratioMental stress ischemiaAdverse cardiac eventsNew perfusion defectsCT myocardial perfusionSensitivity/specificityStress ischemiaArterial tonometryCardiac eventsArtery diseaseBlood pressureACE inhibitionPerfusion defectsHeart rateMyocardial perfusionPatientsEnzyme inhibitorsClinical settingIschemiaOut of Left Field
Marcoff L, Varma P, Vashist A. Out of Left Field. The American Journal Of Medicine 2008, 121: 589-591. PMID: 18589056, DOI: 10.1016/j.amjmed.2008.03.016.Peer-Reviewed Original ResearchScreening for coronary atherosclerosis with coronary calcium scoring: The “shape” of things to come?
Vashist A, Bonow R. Screening for coronary atherosclerosis with coronary calcium scoring: The “shape” of things to come? Journal Of Nuclear Cardiology 2008, 15: 162-169. PMID: 18371586, DOI: 10.1016/j.nuclcard.2008.01.009.Peer-Reviewed Original Research
2007
American Society of Nuclear Cardiology review of the ACCF/ASNC appropriateness criteria for single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI)
Ward R, Al-Mallah M, Grossman G, Hansen C, Hendel R, Kerwin T, McCallister B, Mehta R, Polk D, Tilkemeier P, Vashist A, Williams K, Wolinsky D, Ficaro E. American Society of Nuclear Cardiology review of the ACCF/ASNC appropriateness criteria for single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI). Journal Of Nuclear Cardiology 2007, 14: e26-e38. PMID: 18022098, DOI: 10.1016/j.nuclcard.2007.10.001.Peer-Reviewed Original ResearchDoes cardiac SPECT using attenuation and scatter correction accurately predict coronary artery disease in a minority women population?
Vashist A, Collins D, Prasad Y, Blum S, Heller E. Does cardiac SPECT using attenuation and scatter correction accurately predict coronary artery disease in a minority women population? Medical Science Monitor 2007, 13: cr386-390. PMID: 17767117.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingCoronary artery diseasePositive predictive valueWomen patientsArtery diseaseSensitivity of MPIPredictive valueExercise stress testingGroup of patientsStress testingRecent revascularizationCardiac catheterizationCoronary angiographyFavorable prognosisRisk stratificationCatheterization laboratoryGeneral populationPatientsWomen populationPerfusion imagingAttenuation/scatter correctionNuclear imagingAngiographyPrognosisDiagnostic methods
2006
C-Reactive Protein and Vulnerability to Mental Stress-Induced Myocardial Ischemia
Shah R, Burg MM, Vashist A, Collins D, Liu J, Jadbabaie F, Graeber B, Earley C, Lampert R, Soufer R. C-Reactive Protein and Vulnerability to Mental Stress-Induced Myocardial Ischemia. Molecular Medicine 2006, 12: 269-274. PMID: 17380191, PMCID: PMC1829194, DOI: 10.2119/2006-00077.shah.Peer-Reviewed Original ResearchConceptsC-reactive proteinCoronary artery diseaseMyocardial perfusion imagingTransthoracic echocardiographyCRP levelsMental stressRisk markersMyocardial ischemiaLevels of CRPNew regional wall motion abnormalitiesAssociation of CRPRelationship of CRPSimultaneous single-photon emissionStable coronary artery diseaseUnivariate logistic regression analysisRegional wall motion abnormalitiesTetrofosmin myocardial perfusion imagingLaboratory mental stressRisk of MSISerum CRP levelsHistory of diabetesSubsequent clinical eventsNew perfusion defectsWall motion abnormalitiesLogistic regression analysis
2005
Mental stress ischemia: Present status and future goals
Burg MM, Vashist A, Soufer R. Mental stress ischemia: Present status and future goals. Journal Of Nuclear Cardiology 2005, 12: 523-529. PMID: 16171711, DOI: 10.1016/j.nuclcard.2005.06.085.Peer-Reviewed Original ResearchConceptsEvent-free survival rateLarge-scale clinical trialsAssessment of prognosisForms of ischemiaComplex clinical manifestationsSubstantial clinical impactClinical manifestationsPrognostic significanceClinical trialsClinical impactSurvival rateDiagnostic standardizationTreatment effectsIschemiaNuclear cardiologyPrognosisPathophysiologySufficient evidenceAdditional modalitiesTrialsFurther testingTreatmentPrevalenceCardiologyNoninvasive cardiac imaging in the evaluation of suspected acute coronary syndromes
Vashist A, Abbott B. Noninvasive cardiac imaging in the evaluation of suspected acute coronary syndromes. Expert Review Of Cardiovascular Therapy 2005, 3: 473-486. PMID: 15889975, DOI: 10.1586/14779072.3.3.473.Peer-Reviewed Original ResearchConceptsChest painCoronary syndromeEmergency departmentAcute ischemiaEmission tomographyCardiac magnetic resonance imagingAcute coronary syndromeSingle photon emission tomographyAppropriate clinical settingCoronary artery diseaseReperfusion-induced cell deathImaging modalitiesRadionuclide perfusion studyNoninvasive cardiac imagingCardiac magnetic resonanceMagnetic resonance imagingPositron emission tomographyNoninvasive imaging modalityArtery diseaseSuch patientsRandomized trialsPrognostic valueDiagnostic dilemmaSubendocardial ischemiaUnnecessary hospitalization
2004
Do electrocardiographic changes with adenosine myocardial perfusion imaging predict ischaemia in patients with left ventricular hypertrophy?
Vashist A, Victoria A, Blum S, Bella J, Heller E. Do electrocardiographic changes with adenosine myocardial perfusion imaging predict ischaemia in patients with left ventricular hypertrophy? Nuclear Medicine Communications 2004, 25: 553-556. PMID: 15167513, DOI: 10.1097/01.mnm.0000126630.47661.d9.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineCausalityComorbidityElectrocardiographyExercise TestFemaleHumansHypertrophy, Left VentricularIncidenceMaleMiddle AgedMyocardial IschemiaPrevalencePrognosisRadionuclide ImagingReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityStatistics as TopicUnited StatesConceptsLeft ventricular hypertrophyECG changesVentricular hypertrophyBaseline electrocardiogramElectrocardiographic changesPredictive valueSevere coronary artery diseaseEvidence of ischaemiaCoronary artery diseaseAdenosine myocardial perfusionForm of exercisePresence of collateralsNegative predictive valuePositive predictive valueArtery diseaseConsecutive patientsImaging correlatesTc-sestamibiIschaemiaMyocardial perfusionPatientsX minHypertrophyPerfusionStress test
2002
Renal artery stenosis: A cardiovascular perspective
Vashist A, Heller E, Brown E, Alhaddad I. Renal artery stenosis: A cardiovascular perspective. American Heart Journal 2002, 143: 559-564. PMID: 11923791, DOI: 10.1067/mhj.2002.120769.Peer-Reviewed Original ResearchConceptsRenal artery stenosisRevascularization strategyRenal arteryManagement of RASAggressive risk factor modificationAtherosclerotic renal artery stenosisPercutaneous transluminal angioplasty techniquesAppropriate revascularization strategyRisk factor modificationDiagnosis of RASCongestive heart failureImportant clinical entityProgressive renal failureEffective revascularization strategyNoninvasive screening testSeverity of stenosisMagnetic resonance angiographyTraditional surgical proceduresGeneralized atherosclerosisUncontrolled hypertensionAntiplatelet therapyFibromuscular dysplasiaPatient's hypertensionRenal insufficiencyRenovascular hypertensionAssociation of heart rate response with scan and left ventricular function on adenosine myocardial perfusion imaging
Vashist A, Heller E, Blum S, Brown E, Bhalodkar N. Association of heart rate response with scan and left ventricular function on adenosine myocardial perfusion imaging. The American Journal Of Cardiology 2002, 89: 174-177. PMID: 11792338, DOI: 10.1016/s0002-9149(01)02196-8.Peer-Reviewed Original ResearchConceptsBeats/minMyocardial perfusion imagingEjection fractionAbnormal scansAdenosine myocardial perfusionHeart rate responseVentricular functionScan groupMyocardial perfusionAdenosine myocardial perfusion imagingAbnormal scan groupAdenosine stress testNormal scan groupRate responseNormal ejection fractionLV ejection fractionAverage HRSingle photon emissionConsecutive patientsMean ageNormal scansPeak HRReversible defectsGroup 2HR response
1998
Pregnancy‐induced severe left ventricular systolic dysfunction in a patient with hypertrophic cardiomyopathy
Kazimuddin M, Vashist A, Basher A, Brown E, Alhaddad I. Pregnancy‐induced severe left ventricular systolic dysfunction in a patient with hypertrophic cardiomyopathy. Clinical Cardiology 1998, 21: 848-850. PMID: 9825201, PMCID: PMC6656090, DOI: 10.1002/clc.4960211114.Peer-Reviewed Original Research