2017
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface
Pavličev M, Wagner GP, Chavan AR, Owens K, Maziarz J, Dunn-Fletcher C, Kallapur SG, Muglia L, Jones H. Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface. Genome Research 2017, 27: 349-361. PMID: 28174237, PMCID: PMC5340963, DOI: 10.1101/gr.207597.116.Peer-Reviewed Original ResearchConceptsSingle-cell transcriptomicsG protein-coupled receptorsCell communication networksGene expression profilesReceptor-ligand pairsCell type identificationOrganismal functionInteraction hubTrophoblast cellsGene expressionExpression profilesEndometrial stromal fibroblastsSpecific expressionCell typesInteractomeTranscriptomicsRich resourceCell interactionsPlacental trophoblast cellsDecidual cellsImmune signalsStromal cellsGrowth factorStromal fibroblastsEndometrial stromal cells
2016
What was the ancestral function of decidual stromal cells? A model for the evolution of eutherian pregnancy
Chavan AR, Bhullar BA, Wagner GP. What was the ancestral function of decidual stromal cells? A model for the evolution of eutherian pregnancy. Placenta 2016, 40: 40-51. PMID: 27016782, DOI: 10.1016/j.placenta.2016.02.012.Peer-Reviewed Original ResearchConceptsEutherian mammalsDecidual stromal cellsAncestral functionEutherian cladesMajor lineagesStem lineageEutherian pregnancyStromal cellsEutherian speciesStem eutheriansExtended gestationMammalsEutheriansLineagesMaintenance of pregnancyCellsInvasive placentationLaurasiatheriaCladeEuarchontogliresAfrotheriaFetal-maternal interfaceXenarthraDecidual cellsSpecies