Neural correlates of substance abuse: Reduced functional connectivity between areas underlying reward and cognitive control
Motzkin JC, Baskin‐Sommers A, Newman JP, Kiehl KA, Koenigs M. Neural correlates of substance abuse: Reduced functional connectivity between areas underlying reward and cognitive control. Human Brain Mapping 2014, 35: 4282-4292. PMID: 24510765, PMCID: PMC4107096, DOI: 10.1002/hbm.22474.Peer-Reviewed Original ResearchConceptsCognitive-behavioral controlCognitive controlSubstance use disordersFunctional connectivityFrontal cortical regionsSUD groupIndividual differencesResting-state functional connectivityCortical regionsAnterior cingulate cortexAdult male prison inmatesLower functional connectivityMale prison inmatesNeural correlatesNucleus accumbensPsychological correlatesReward processingNeurocircuitry modelsCingulate cortexGroup differencesBrain regionsSubstance abuseDorsal caudateHabit formationUse disorders