Maternal regulation of the vertebrate oocyte-to-embryo transition
Fuentes R, Marlow F, Abrams E, Zhang H, Kobayashi M, Gupta T, Kapp L, DiNardo Z, Heller R, Cisternas R, García-Castro P, Segovia-Miranda F, Montecinos-Franjola F, Vought W, Vejnar C, Giraldez A, Mullins M. Maternal regulation of the vertebrate oocyte-to-embryo transition. PLOS Genetics 2024, 20: e1011343. PMID: 39052672, PMCID: PMC11302925, DOI: 10.1371/journal.pgen.1011343.Peer-Reviewed Original ResearchOocyte-to-embryo transitionMutant geneZebrafish forward genetic screenEgg activationForward genetic screensGenetic entry pointsMaternal-effect mutantsBasic body planCytoplasmic segregationBody planIntracellular traffickingGenetic screeningMicrotubule nucleationProtein cleavageMaternal genesVesicle formationGenesFunctional importanceHuman diseasesMolecular mechanismsMolecular insightsCortical granulesBlack caviarMaternal regulationMolecular nature