2001
Hemangioblast Commitment in the Avian Allantois: Cellular and Molecular Aspects
Caprioli A, Minko K, Drevon C, Eichmann A, Dieterlen-Lièvre F, Jaffredo T. Hemangioblast Commitment in the Avian Allantois: Cellular and Molecular Aspects. Developmental Biology 2001, 238: 64-78. PMID: 11783994, DOI: 10.1006/dbio.2001.0362.Peer-Reviewed Original ResearchMeSH KeywordsAllantoisAnimalsCell LineageChick EmbryoCoturnixDNA-Binding ProteinsEndodermErythroid-Specific DNA-Binding FactorsGATA2 Transcription FactorGATA3 Transcription FactorHematopoietic Stem CellsImmunohistochemistryIn Situ HybridizationLeukocyte Common AntigensMesodermModels, BiologicalProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorRNA, MessengerTime FactorsTrans-ActivatorsTranscription FactorsConceptsGATA-2Allantoic budCommitment of mesodermTranscription factor GATA-2SCL/talHemopoietic cellsHemangioblast commitmentEndoderm specificationOrgan formationGATA-1Definitive lineageStage HH17Blood islandsBlood island-like structuresEndodermMolecular processesMesodermEngrafted hostsMolecular aspectsHemopoietic lineagesGene patternsYolk sacBudsQuail embryosEmbryosEndogenous origin of the lymphatics in the avian chorioallantoic membrane
Papoutsi M, Tomarev S, Eichmann A, Pröls F, Christ B, Wilting J. Endogenous origin of the lymphatics in the avian chorioallantoic membrane. Developmental Dynamics 2001, 222: 238-251. PMID: 11668601, DOI: 10.1002/dvdy.1187.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationChick EmbryoChickensChimeraChorionEndothelial Growth FactorsEndothelium, LymphaticGene Expression Regulation, DevelopmentalHomeodomain ProteinsMesodermQuailReceptor Protein-Tyrosine KinasesReceptors, Growth FactorTumor Suppressor ProteinsVascular Endothelial Growth Factor CVascular Endothelial Growth Factor Receptor-3ConceptsVascular endothelial growth factor receptor 3Allantoic budSplanchnic mesodermAllantoic mesodermHematopoietic cellsMesenchymal cellsQuail embryosChorioallantoic membraneEndothelial cellsGrowth factor receptor 3Intraembryonic sitesBlood islandsMesodermAllantoic epitheliumEmbryosEndothelial networksBudsAvian chorioallantoic membraneDay 4 embryosImportant functionsMRNA probesLymphangiogenic potentialLymphatic endotheliumCAM developmentChick embryosPlasticity of endothelial cells during arterial-venous differentiation in the avian embryo.
Moyon D, Pardanaud L, Yuan L, Bréant C, Eichmann A. Plasticity of endothelial cells during arterial-venous differentiation in the avian embryo. Development 2001, 128: 3359-70. PMID: 11546752, DOI: 10.1242/dev.128.17.3359.Peer-Reviewed Original ResearchConceptsArterial-venous differentiationEndothelial plasticityEndothelial cellsEmbryonic day 7Jugular veinDay 7Vessel wallPrimary vascular systemNeuropilin-1Quail-chick chimerasHost arteryVenous fateEmbryonic developmentTransmembrane receptorsVenous markersEmbryonic day 2Venous endothelial cellsAortic endothelial cellsAvian embryosVascular developmentMost arteriesCarotid arteryVessel identityDay 11 embryosDorsal aortaSelective expression of angiopoietin 1 and 2 in mesenchymal cells surrounding veins and arteries of the avian embryo
Moyon D, Pardanaud L, Yuan L, Bréant C, Eichmann A. Selective expression of angiopoietin 1 and 2 in mesenchymal cells surrounding veins and arteries of the avian embryo. Cells And Development 2001, 106: 133-136. PMID: 11472842, DOI: 10.1016/s0925-4773(01)00425-7.Peer-Reviewed Original ResearchMeSH KeywordsAngiopoietin-1Angiopoietin-2AnimalsAortaArteriesChick EmbryoDown-RegulationEndothelium, VascularGene Expression Regulation, DevelopmentalHeartIn Situ HybridizationLymphatic SystemMembrane GlycoproteinsMesodermNeoplasm ProteinsProteinsProto-Oncogene ProteinsQuailReceptor, TIE-2RNA, MessengerVeins
1999
Récepteurs et développement des cellules endothéliales et hématopoïétiques
Eichmann A, Moyon D, Corbel C. Récepteurs et développement des cellules endothéliales et hématopoïétiques. Biologie Aujourd Hui 1999, 193: 155-157. PMID: 10451349, DOI: 10.1051/jbio/1999193020155.Peer-Reviewed Original Research
1998
Segregation of the embryonic vascular and hemopoietic systems
Eichmann A, Corbel C, Le Douarin N. Segregation of the embryonic vascular and hemopoietic systems. Biochemistry And Cell Biology 1998, 76: 939-946. PMID: 10392707, DOI: 10.1139/o98-106.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCell DifferentiationChick EmbryoEmbryo, NonmammalianEndothelial Growth FactorsEndothelium, VascularHematopoietic Stem CellsLymphokinesMesodermMiceModels, CardiovascularQuailReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsEndothelial precursor cellsAvian embryosPrecursor cellsVEGF receptor VEGFR2Primary vascular systemEndothelial cellsGastrulation stageGrowth factorDevelopmental biologyVertebrate classesSpecific growth factorsVascular endothelial growth factorAngiogenic vascular endothelial growth factorMouse embryosMolecular mechanismsCognate receptorsSubsequent assemblyHemopoietic cellsEmbryosReceptor VEGFR2Hemopoietic systemCulture experimentsVEGFR2CellsSignificant insightsAvian VEGF-C: cloning, embryonic expression pattern and stimulation of the differentiation of VEGFR2-expressing endothelial cell precursors
Eichmann A, Corbel C, Jaffredo T, Bréant C, Joukov V, Kumar V, Alitalo K, le Douarin N. Avian VEGF-C: cloning, embryonic expression pattern and stimulation of the differentiation of VEGFR2-expressing endothelial cell precursors. Development 1998, 125: 743-752. PMID: 9435294, DOI: 10.1242/dev.125.4.743.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCell DifferentiationCloning, MolecularDNA, ComplementaryEndothelial Growth FactorsEndothelium, VascularGene Expression Regulation, DevelopmentalIn Situ HybridizationMesodermMiceMolecular Sequence DataProtein BindingQuailReceptor Protein-Tyrosine KinasesReceptors, Cell SurfaceReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorRecombinant ProteinsSequence Homology, Amino AcidStem CellsVascular Endothelial Growth Factor CVascular Endothelial Growth Factor Receptor-3
1997
Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2
Eichmann A, Corbel C, Nataf V, Vaigot P, Bréant C, Le Douarin N. Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 5141-5146. PMID: 9144204, PMCID: PMC24645, DOI: 10.1073/pnas.94.10.5141.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalCell DifferentiationChick EmbryoEndothelial Growth FactorsEndothelium, VascularGastrulaHematopoietic Stem CellsHomozygoteLigandsLymphokinesMesodermMiceMice, Inbred BALB CMice, KnockoutQuailReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsVascular endothelial growth factor receptor 2VEGFR2 ligandsEndothelial growth factor receptor 2Embryonic mesodermal cellsVascular endothelial lineageHemopoietic cellsDevelopmental decisionsGastrulation stageHomozygous null miceMesodermal cellsAbsence of VEGFGene productsGene targetingNull mutationEndothelial lineageHemopoietic differentiationExtracellular domainClonal culturesLineagesHemopoietic lineagesEndothelial differentiationEndothelial cell coloniesCell coloniesCell microenvironmentGrowth factor receptor 2
1995
The angiogenic potentials of the cephalic mesoderm and the origin of brain and head blood vessels
Couly G, Coltey P, Eichmann A, Le Douarin N. The angiogenic potentials of the cephalic mesoderm and the origin of brain and head blood vessels. Cells And Development 1995, 53: 97-112. PMID: 8555115, DOI: 10.1016/0925-4773(95)00428-9.Peer-Reviewed Original ResearchConceptsCephalic paraxial mesodermParaxial mesodermCephalic mesodermAnterior paraxial mesodermBlood vessel endothelial cellsQuail-chick chimera techniqueVessel endothelial cellsEarly avian embryoEndothelial cellsOrigin of brainGastrulation stageMesodermal territoryMesodermal cellsQuail speciesAngiogenic potentialMesodermNeural crestNeural primordiumMolecular markersAvian embryosAvian homologueHigh growth rateStage-matched embryosHemopoietic cellsFlk-1