2004
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
Lu X, le Noble F, Yuan L, Jiang Q, de Lafarge B, Sugiyama D, Bréant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 2004, 432: 179-186. PMID: 15510105, DOI: 10.1038/nature03080.Peer-Reviewed Original ResearchConceptsNetrin receptor UNC5BEndothelial tip cell filopodiaTip cell filopodiaReceptor UNC5BEndothelial tip cellsVascular systemNetrin-1aTip cellsEndothelial cellsProper wiringAxon guidanceCell filopodiaNetrin receptorsGuidance eventsFilopodial retractionMorphogenesisUNC5BVessel branchingAberrant extensionAnatomical similaritiesNetrin-1CellsZebrafishGenesGuidance function
2001
Hemangioblast Commitment in the Avian Allantois: Cellular and Molecular Aspects
Caprioli A, Minko K, Drevon C, Eichmann A, Dieterlen-Lièvre F, Jaffredo T. Hemangioblast Commitment in the Avian Allantois: Cellular and Molecular Aspects. Developmental Biology 2001, 238: 64-78. PMID: 11783994, DOI: 10.1006/dbio.2001.0362.Peer-Reviewed Original ResearchMeSH KeywordsAllantoisAnimalsCell LineageChick EmbryoCoturnixDNA-Binding ProteinsEndodermErythroid-Specific DNA-Binding FactorsGATA2 Transcription FactorGATA3 Transcription FactorHematopoietic Stem CellsImmunohistochemistryIn Situ HybridizationLeukocyte Common AntigensMesodermModels, BiologicalProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorRNA, MessengerTime FactorsTrans-ActivatorsTranscription FactorsConceptsGATA-2Allantoic budCommitment of mesodermTranscription factor GATA-2SCL/talHemopoietic cellsHemangioblast commitmentEndoderm specificationOrgan formationGATA-1Definitive lineageStage HH17Blood islandsBlood island-like structuresEndodermMolecular processesMesodermEngrafted hostsMolecular aspectsHemopoietic lineagesGene patternsYolk sacBudsQuail embryosEmbryosSelective expression of angiopoietin 1 and 2 in mesenchymal cells surrounding veins and arteries of the avian embryo
Moyon D, Pardanaud L, Yuan L, Bréant C, Eichmann A. Selective expression of angiopoietin 1 and 2 in mesenchymal cells surrounding veins and arteries of the avian embryo. Cells And Development 2001, 106: 133-136. PMID: 11472842, DOI: 10.1016/s0925-4773(01)00425-7.Peer-Reviewed Original ResearchMeSH KeywordsAngiopoietin-1Angiopoietin-2AnimalsAortaArteriesChick EmbryoDown-RegulationEndothelium, VascularGene Expression Regulation, DevelopmentalHeartIn Situ HybridizationLymphatic SystemMembrane GlycoproteinsMesodermNeoplasm ProteinsProteinsProto-Oncogene ProteinsQuailReceptor, TIE-2RNA, MessengerVeins
1992
Molecular cloning of a family of protein kinase genes expressed in the avian embryo.
Marcelle C, Eichmann A. Molecular cloning of a family of protein kinase genes expressed in the avian embryo. Oncogene 1992, 7: 2479-87. PMID: 1281306.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBlastocystChick EmbryoChickensCloning, MolecularEmbryo, NonmammalianGene ExpressionMolecular Sequence DataMultigene FamilyNervous SystemNeural CrestOligodeoxyribonucleotidesOrgan SpecificityPhylogenyPoly APolymerase Chain ReactionProtein KinasesProtein-Tyrosine KinasesQuailReceptors, Cell SurfaceRNARNA, MessengerSequence Homology, Amino AcidSequence Homology, Nucleic AcidTranscription, GeneticConceptsReceptor tyrosine kinasesPKS genesGrowth factor receptorPutative receptor tyrosine kinaseTyrosine kinaseSerine/threonine kinaseProtein kinase sequencesEarly vertebrate developmentProtein kinase geneCytosolic tyrosine kinasesFactor receptorFibroblast growth factor receptorGrowth factor receptor tyrosine kinasePlatelet-derived growth factor receptor alphaGrowth factor receptor alphaNorthern blot analysisPattern of expressionReceptor-like moleculesVertebrate developmentInsulin-like growth factor type I receptorKinase sequencesType I receptorThreonine kinaseMore transcriptsAvian homolog