2007
Biomechanical Gene Activation During Cardiovascular Development
Jones E, Le Noble F, Yuan L, Eichmann A. Biomechanical Gene Activation During Cardiovascular Development. The FASEB Journal 2007, 21: a201-a201. DOI: 10.1096/fasebj.21.5.a201-a.Peer-Reviewed Original ResearchCardiovascular developmentPhysical forcesGene activationEmbryonic developmentVenous differentiationBiochemical signalingMechanical cuesGene expressionEmbryo growthEphB4 receptorVascular formationNeuropilin-2Mechanical forcesNeuropilin-1Blood fluid dynamicsExternal stimuliGenesCardiovascular systemSignalingEmbryosEphrinB2DifferentiationRegulationDynamic interactionExpression
2004
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
Lu X, le Noble F, Yuan L, Jiang Q, de Lafarge B, Sugiyama D, Bréant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 2004, 432: 179-186. PMID: 15510105, DOI: 10.1038/nature03080.Peer-Reviewed Original ResearchConceptsNetrin receptor UNC5BEndothelial tip cell filopodiaTip cell filopodiaReceptor UNC5BEndothelial tip cellsVascular systemNetrin-1aTip cellsEndothelial cellsProper wiringAxon guidanceCell filopodiaNetrin receptorsGuidance eventsFilopodial retractionMorphogenesisUNC5BVessel branchingAberrant extensionAnatomical similaritiesNetrin-1CellsZebrafishGenesGuidance function
1993
Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development
Eichmann A, Marcelle C, Bréant C, Le Douarin N. Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development. Cells And Development 1993, 42: 33-48. PMID: 8396413, DOI: 10.1016/0925-4773(93)90096-g.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChick EmbryoCloning, MolecularEmbryo, NonmammalianEndothelium, VascularMolecular Sequence DataProtein-Tyrosine KinasesQuailReceptor Protein-Tyrosine KinasesReceptors, MitogenReceptors, NeurotransmitterReceptors, Vascular Endothelial Growth FactorSequence Homology, Nucleic AcidVascular Endothelial Growth Factor Receptor-2ConceptsExpression patternsOnset of gastrulationAvian embryonic developmentEndothelial cellsEarly endothelial cellsMonoclonal antibody QH1Human genesEmbryonic developmentEmbryonic day 9Vascular endothelial growth factorHigh homologyHematopoietic lineagesAvian embryosPartial cloningSitu hybridizationReceptor moleculesGastrulationPutative precursorEndothelial cell mitogen vascular endothelial growth factorFlk-1GenesEmbryosGrowth factorQH1VEGF receptors