2024
Urinary Tract Infection and Progression to Pyelonephritis: Group B Streptococcus versus E. coli
Sachdeva S, Rosett H, Krischak M, Weaver K, Heine R, Denoble A, Dotters-Katz S. Urinary Tract Infection and Progression to Pyelonephritis: Group B Streptococcus versus E. coli. American Journal Of Perinatology Reports 2024, 14: e80-e84. PMID: 38370326, PMCID: PMC10874690, DOI: 10.1055/s-0044-1779031.Peer-Reviewed Original ResearchLower urinary tract infectionsLow birth weightUrinary tract infectionHistory of ACLength of stayPreterm deliveryGestational agePreterm birthTract infectionsPregnant womenRetrospective cohort of pregnant womenGroup B <i>Streptococcus</i> (GBPrimary outcomeHistory of preterm birthMedical records of womenCohort of pregnant womenLow birth weight rateAssociated with severe infectionsMedian gestational ageMedian length of stayGroup B streptococciLower urinary tractRecords of womenPrimary infection typeMedian GA
2023
Associations between Anemia and Outcomes of Pregnant Patients with Pyelonephritis
Cunningham H, Knochenhauer H, Federspiel J, Wein L, Denoble A, Heine R, Dotters-Katz S. Associations between Anemia and Outcomes of Pregnant Patients with Pyelonephritis. American Journal Of Perinatology 2023, 41: e2403-e2409. PMID: 37339672, PMCID: PMC10799185, DOI: 10.1055/a-2113-2892.Peer-Reviewed Original ResearchSevere maternal morbidityNationwide Readmissions DatabaseMaternal morbidityPregnant patientsAcute respiratory distress syndromeAdverse maternal outcomesLonger hospital stayAcute renal failureDisease Control criteriaRetrospective cohort studyRespiratory distress syndromeWeighted national estimateComplex survey methodsMaternal comorbiditiesNonanemic patientsHospital stayMaternal outcomesBaseline characteristicsRenal failureCohort studyDistress syndromePrimary outcomeSepsis riskAnemic patientsClinical comorbidities
2022
Impact of Pre-Existing Ischemic Heart Disease on Severe Maternal Morbidity and Mortality During Delivery Hospitalizations
Denoble A, Goldstein S, Wein L, Grotegut C, Federspiel J. Impact of Pre-Existing Ischemic Heart Disease on Severe Maternal Morbidity and Mortality During Delivery Hospitalizations. JACC Advances 2022, 1: 100157. PMID: 36684662, PMCID: PMC9851052, DOI: 10.1016/j.jacadv.2022.100157.Peer-Reviewed Original ResearchSevere maternal morbidityIschemic heart diseaseDelivery hospitalizationsComplex survey methodsCardiac diseaseCardiac diagnosisMaternal morbidityHeart diseasePre-existing ischaemic heart diseasePre-existing ischemic heart diseaseNontransfusion severe maternal morbidityWorld Health Organization classificationClass IAdverse pregnancy outcomesNationwide Readmissions DatabaseRelative risk regressionWorld Health Organization class IPregnancy outcomesPrimary outcomeRetrospective studyAdverse outcomesUnadjusted analysesOrganization classificationRisk regressionWorse outcomesComparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk
Denoble AE, Goldstein SA, Wein LE, Grotegut CA, Federspiel JJ. Comparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk. American Heart Journal 2022, 250: 11-22. PMID: 35526569, PMCID: PMC9836743, DOI: 10.1016/j.ahj.2022.04.009.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityWorld Health Organization classificationDelivery hospitalizationsCardiac diagnosisMaternal morbidityOrganization classificationMaternal cardiovascular riskNationwide Readmissions DatabaseRisk of deathSevere cardiac diseaseWeighted national estimateMWHO classificationDelivery admissionCardiovascular riskPregnant patientsSecondary outcomesPrimary outcomeRetrospective studyYear postpartumPregnancy counselingPrimary exposureMonths postpartumNationwide databaseCardiac diseaseElevated risk
2021
Pregnancy Outcomes among Women with Class III Obesity with Pre-diabetic Early Hemoglobin A1C
Dillon J, Mitchell CJ, Ellett T, Siegel A, Denoble AE, Dotters-Katz SK. Pregnancy Outcomes among Women with Class III Obesity with Pre-diabetic Early Hemoglobin A1C. American Journal Of Perinatology 2021, 39: 238-242. PMID: 34891200, DOI: 10.1055/s-0041-1739358.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusClass III obesityBody mass indexPre-diabetic rangeGestational diabetesA1C 5.7Normal A1CPrimary outcomeGestational ageDevelopment of GDMClass III obese womenDelivery body mass indexNon-anomalous singleton pregnanciesMaternal body mass indexLow-A1C groupFetal growth restrictionInduction of laborHigh-risk populationA1c groupMedian A1CPregnancy complicationsBaseline demographicsCesarean deliveryMultiple gestationsObese womenPregnancy outcomes among women with class III obesity with normal early glucola
Ellett T, Mitchell CJ, Dillon J, Siegel A, Denoble AE, Dotters-Katz S. Pregnancy outcomes among women with class III obesity with normal early glucola. The Journal Of Maternal-Fetal & Neonatal Medicine 2021, 35: 5834-5839. PMID: 33818267, DOI: 10.1080/14767058.2021.1895741.Peer-Reviewed Original ResearchConceptsBody mass indexRate of GDMGlucose challenge testGestational diabetesObese womenPrimary outcomeGestational ageChallenge testDelivery body mass indexNon-anomalous singleton pregnanciesMaternal body mass indexOral glucose challenge testClass 3 obesityDevelopment of GDMClass III obesityGestational diabetes mellitusFetal growth restrictionInduction of laborNeonatal birthweightPregnancy complicationsBaseline demographicsCesarean deliveryMultiple gestationsPregnancy outcomesRetrospective cohort
2020
Beyond Expert Opinion: A Comparison of Antibiotic Regimens for Infectious Urinary Tract Pathology in Pregnancy
Krischak MK, Rosett HA, Sachdeva S, Weaver KE, Heine RP, Denoble AE, Dotters-Katz SK. Beyond Expert Opinion: A Comparison of Antibiotic Regimens for Infectious Urinary Tract Pathology in Pregnancy. American Journal Of Perinatology Reports 2020, 10: e352-e356. PMID: 33094027, PMCID: PMC7571572, DOI: 10.1055/s-0040-1718384.Peer-Reviewed Original ResearchLower urinary tract infectionsFirst-line therapyLow birth weightPreterm birthSMZ-TMPSingle health care systemAdverse obstetric outcomesOdds of progressionReceipt of antibioticsRisk of progressionUrinary tract infectionLength of stayUrinary tract pathologyOdds of outcomesHealth care systemAcute cystitisAsymptomatic bacteriuriaAntibiotic regimensObstetric outcomesOutside pregnancyRetrospective cohortSecondary outcomesTract infectionsPrimary outcomeOptimal antibioticsChorioamnionitis versus intraamniotic infection among preterm deliveries—is postpartum infectious morbidity different?
Denoble AE, Wu J, Mitchell CJ, Hughes BL, Dotters-Katz SK. Chorioamnionitis versus intraamniotic infection among preterm deliveries—is postpartum infectious morbidity different? American Journal Of Obstetrics & Gynecology MFM 2020, 2: 100176. PMID: 33345890, DOI: 10.1016/j.ajogmf.2020.100176.Peer-Reviewed Original ResearchConceptsPostpartum infectious morbidityIntraamniotic infectionClinical chorioamnionitisPostpartum endometritisAntibiotic treatmentMaternal temperatureAmerican CollegeInfectious morbidityPreterm deliveryPotential confoundersGynecologists criteriaAdditional clinical risk factorsAntenatal magnesium sulfateIntrapartum antibiotic treatmentPostpartum endometritis ratePostpartum infectious complicationsClinical risk factorsMultivariate logistic regressionOriginal study populationProportion of womenEndometritis ratesFetal morbidityInfectious complicationsPreterm birthPrimary outcomeRisk Factors for Postpartum Maternal Infection Following Spontaneous Vaginal Delivery Complicated by Chorioamnionitis
Daifotis H, Smith M, Denoble A, Dotters-Katz S. Risk Factors for Postpartum Maternal Infection Following Spontaneous Vaginal Delivery Complicated by Chorioamnionitis. American Journal Of Perinatology Reports 2020, 10: e159-e164. PMID: 32426175, PMCID: PMC7228805, DOI: 10.1055/s-0040-1709983.Peer-Reviewed Original ResearchSpontaneous vaginal deliveryPostpartum infectionPrimary outcomeVaginal deliveryRisk factorsManagement of chorioamnionitisPostpartum maternal infectionHigh-risk womenIntrapartum antibioticsPostpartum antibioticsMaternal infectionWeeks' gestationSingle centerRetrospective studyAdjusted oddsAntibiotic useChorioamnionitisInfectionWomenBivariate statisticsGestationOutcomesWeeksRegression modelsOddsUsing the new definition of intraamniotic infection – is there morbidity among the women left out?
Smith MM, Daifotis HA, DeNoble AE, Dotters-Katz SK. Using the new definition of intraamniotic infection – is there morbidity among the women left out? The Journal Of Maternal-Fetal & Neonatal Medicine 2020, 34: 4148-4152. PMID: 31928262, DOI: 10.1080/14767058.2020.1711723.Peer-Reviewed Original ResearchConceptsPostpartum infectionIntraamniotic infectionPrimary outcomePostpartum infectious morbidityUrinary tract infectionSingle academic centerFourth-degree lacerationsBackward stepwise eliminationACOG criteriaAntibiotic receiptGestational hypertensionIntrapartum characteristicsMaternal feverMaternal tachycardiaDegree lacerationsInfectious morbidityRetrospective cohortTract infectionsDiagnostic criteriaAcademic centersInfectionWomenBivariate statisticsMorbidityFever
2019
Chorioamnionitis and Infectious Complications after Vaginal Delivery
DeNoble AE, Heine RP, Dotters-Katz SK. Chorioamnionitis and Infectious Complications after Vaginal Delivery. American Journal Of Perinatology 2019, 36: 1437-1441. PMID: 31238347, DOI: 10.1055/s-0039-1692718.Peer-Reviewed Original ResearchConceptsBody mass indexPostpartum infectious complicationsPostpartum infectionPostpartum antibioticsInfectious complicationsPreterm deliveryPrimary outcomeVaginal deliveryMaternal-Fetal Medicine Unit Cesarean RegistryPrepregnancy body mass indexSeptic pelvic thrombophlebitisUrinary tract infectionCesarean RegistryEunice KennedyPelvic thrombophlebitisSuccessful VBACTract infectionsMass indexPelvic abscessVaginal birthRisk factorsMultivariate predictorsChild healthMultivariate analysisChorioamnionitisSpiking in the Second Stage: What are the Neonatal Implications? [19D]
Daifotis H, Smith M, Denoble A, Dotters-Katz S. Spiking in the Second Stage: What are the Neonatal Implications? [19D]. Obstetrics And Gynecology 2019, 133: 47s-46s. DOI: 10.1097/01.aog.0000558975.44644.1a.Peer-Reviewed Original ResearchSevere neonatal morbidityLength of stayNeonatal morbidityMaternal feverNICU admissionUntreated womenTerm singleton vaginal deliveriesInvasive respiratory supportSingleton vaginal deliveriesAntepartum complicationsAntibiotic receiptNeonatal implicationsPostnatal antibioticsACOG guidelinesRespiratory supportRetrospective cohortInfectious signsPrimary outcomeSevere morbidityVaginal deliveryMaternal treatmentUntreated groupMorbidityIRB approvalNeonatesUsing the New Definition of Intraamniotic Infection: Is There Morbidity in the Women Left Out? [27D]
Smith M, Daifotis H, Denoble A, Dotters-Katz S. Using the New Definition of Intraamniotic Infection: Is There Morbidity in the Women Left Out? [27D]. Obstetrics And Gynecology 2019, 133: 50s-48s. DOI: 10.1097/01.aog.0000558983.61677.1d.Peer-Reviewed Original ResearchPostpartum infectious morbidityIntraamniotic infectionUrinary tract infectionInfectious morbidityPrimary outcomeSingle academic centerBackward stepwise eliminationAntibiotic receiptGestational hypertensionIntrapartum characteristicsMaternal feverMaternal tachycardiaDegree lacerationsRetrospective cohortTract infectionsAmerican CollegeDiagnostic criteriaAcademic centersIRB approvalMorbidityMore symptomsInfectionWomenBivariate statisticsChorioamnionitisSpiking in the Second Stage: The Significance of Isolated Maternal Fever During Labor [16A]
Smith M, Daifotis H, Denoble A, Dotters-Katz S. Spiking in the Second Stage: The Significance of Isolated Maternal Fever During Labor [16A]. Obstetrics And Gynecology 2019, 133: 14s-14s. DOI: 10.1097/01.aog.0000559363.72958.65.Peer-Reviewed Original ResearchAdverse maternal outcomesMaternal outcomesAntibiotic receiptPostpartum infectionMaternal feverBlood transfusionAdverse postpartum outcomesIsolated maternal feverPostpartum maternal outcomesPostpartum venous thromboembolismRetrospective cohort studyTwin vaginal deliverySigns of infectionTiming of deliveryAntepartum complicationsDelivery BMIIntraamniotic infectionMaternal morbidityVenous thromboembolismCohort studyHospital readmissionPrimary outcomeVaginal deliveryPostpartum outcomesNineteen womenFactors Associated with Utilization of 17-Hydroxyprogesterone Caproate for the Prevention of Recurrent Preterm Birth
DeNoble AE, Wynn CE, Weaver KE, Wheeler SM, Swamy GK. Factors Associated with Utilization of 17-Hydroxyprogesterone Caproate for the Prevention of Recurrent Preterm Birth. American Journal Of Perinatology 2019, 37: 264-270. PMID: 30708392, DOI: 10.1055/s-0039-1678532.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPrior term birthPrenatal care initiationEligible womenPreterm birthPrimary outcomeTerm birthsWeeks' gestationCare initiationHispanic ethnicityRecurrent spontaneous preterm birthSingleton spontaneous preterm birthPrior spontaneous preterm birthRecurrent preterm birthRetrospective cohort studyAcademic health systemStepwise logistic regressionSPTB rateCohort studyEligible subjectsSingleton pregnanciesClinical predictorsPoor adherenceMaternal ageCare barriers
2014
Receipt of Prescription Contraception by Commercially Insured Women With Chronic Medical Conditions
DeNoble AE, Hall KS, Xu X, Zochowski MK, Piehl K, Dalton VK. Receipt of Prescription Contraception by Commercially Insured Women With Chronic Medical Conditions. Obstetrics And Gynecology 2014, 123: 1213-1220. PMID: 24807345, PMCID: PMC4169713, DOI: 10.1097/aog.0000000000000279.Peer-Reviewed Original ResearchConceptsChronic medical conditionsPrescription contraceptionChronic conditionsMedical conditionsCommunity-level socioeconomic statusAdministrative claims recordsTotal outpatient visitsInflammatory bowel diseaseSystemic lupus erythematosusCervical cancer screeningMultivariable logistic regressionChronic condition statusBowel diseaseLupus erythematosusOrder of prevalencePharmacy claimsPrimary outcomeOutpatient visitsRheumatoid arthritisAdverse outcomesCancer screeningUnplanned pregnancyObservational studyStudy populationInsured women