Annalies Denoble, MD, MSc
Assistant Professor of Obstetrics, Gynecology and Reproductive SciencesCards
About
Research
Overview
As an Assistant Professor in Obstetrics & Gynecology and a board-eligible maternal-fetal medicine specialist, Dr. Denoble's goal is to improve our understanding of cardiovascular diseases in pregnancy and the postpartum period through innovative, patient-relevant research. Cardiac disease is the leading cause of maternal mortality in the United States, but evidence-based strategies for diagnosing, treating, and preventing cardiovascular disease in pregnancy remain limited. Her clinical research involves improving the accuracy of risk prediction models for both adverse cardiac events in pregnancy and severe maternal morbidity and mortality. Ultimately, her goal is to develop strategies that can be employed in the pre-conception and early pregnancy period to better mitigate the risks of pre-existing cardiac disease in pregnancy. Her prior research focused on differences in clinical biomarkers of heart failure between pregnant women with and without obesity, given that obesity is a risk factor for cardiac disease and may complicate the diagnosis of cardiovascular complications in pregnancy. Her background in clinical research through a Master of Science in Clinical Research provides a solid foundation upon which to build her investigation.
She also conducts epidemiologic and clinical research in preeclampsia and hypertension in pregnancy, vaccine safety in pregnancy, and infections in pregnancy.
Medical Subject Headings (MeSH)
Clinical Care
Overview
Annalies Denoble, MD, is an obstetrician-gynecologist who specializes in maternal-fetal medicine, or high-risk pregnancies.
“I have been passionate about women’s health for a long time. I see women as the center of health for the whole family,” she says. “The interplay of physiology of the mom and the fetus during pregnancy is fascinating—you always have to think about two patients and not just one.”
Dr. Denoble says she was drawn to maternal-fetal medicine for its diversity of tasks. “We get to read ultrasounds for routine prenatal care. We deliver babies. We handle complex cases. You never have two days that are the same,” she says. “Plus, there is so much we can do to help patients. Many of the women we take care of have had high-risk pregnancies in the past and they are anxious. Being able to walk with them throughout their pregnancy is incredibly rewarding.”
Part of her approach to patient care is giving women the opportunity to voice their concerns, Dr. Denoble says. “Sometimes just being able to voice what they are most worried about helps them feel more confident moving forward. I also make sure they know that I am there with them throughout their pregnancy, regardless of what decisions they make,” she adds.
Dr. Denoble’s clinical and research interests include maternal heart disease in pregnancy. As the leading cause of maternal mortality in the United States, addressing gaps in our understanding of heart disease in pregnancy is critical to improving maternal health.
Clinical Specialties
Fact Sheets
Hypertension (High Blood Pressure) During Pregnancy
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Board Certifications
Maternal-Fetal Medicine
- Certification Organization
- AB of Obstetrics & Gynecology
- Original Certification Date
- 2024
Obstetrics & Gynecology
- Certification Organization
- AB of Obstetrics & Gynecology
- Original Certification Date
- 2020
Yale Medicine News
Links & Media
News
- July 29, 2024
5 Things To Know About Heart Disease and Pregnancy
- July 01, 2024
2024 Ob/Gyn Research and Graduation Day
- June 07, 2024
Study Finds No Association Between COVID-19 Vaccines and Stillbirths
- December 12, 2023Source: Yale Medicine
Preeclampsia: 3 Things Women Should Know