2010
Cellular choreography in the germinal center: new visions from in vivo imaging
Hauser AE, Kerfoot SM, Haberman AM. Cellular choreography in the germinal center: new visions from in vivo imaging. Seminars In Immunopathology 2010, 32: 239-255. PMID: 20614218, PMCID: PMC3659422, DOI: 10.1007/s00281-010-0214-z.Peer-Reviewed Original Research
2009
Taking Advantage: High-Affinity B Cells in the Germinal Center Have Lower Death Rates, but Similar Rates of Division, Compared to Low-Affinity Cells
Anderson SM, Khalil A, Uduman M, Hershberg U, Louzoun Y, Haberman AM, Kleinstein SH, Shlomchik MJ. Taking Advantage: High-Affinity B Cells in the Germinal Center Have Lower Death Rates, but Similar Rates of Division, Compared to Low-Affinity Cells. The Journal Of Immunology 2009, 183: 7314-7325. PMID: 19917681, PMCID: PMC4106706, DOI: 10.4049/jimmunol.0902452.Peer-Reviewed Original ResearchConceptsLow-affinity B cellsLow-affinity cellsGerminal centersB cellsHigh-affinity B cellsHigh-affinity cellsDeath rateHigh death rateLower death ratesImmune responseHigh-affinity AbsB lymphocytesMemory responsesExtracellular pathogensSame AgPrimary responseGC reactionProliferative advantageSimilar ratesSurvivalCellsCell cycleControl of survivalHigh affinityResponse