2020
Persistent STAG2 mutation despite multimodal therapy in recurrent pediatric glioblastoma
Hong CS, Vasquez JC, Kundishora AJ, Elsamadicy AA, Beckta JM, Sule A, Marks AM, Leelatian N, Huttner A, Bindra RS, DiLuna ML, Kahle KT, Erson-Omay EZ. Persistent STAG2 mutation despite multimodal therapy in recurrent pediatric glioblastoma. Npj Genomic Medicine 2020, 5: 23. PMID: 32528726, PMCID: PMC7264170, DOI: 10.1038/s41525-020-0130-7.Peer-Reviewed Original ResearchPediatric patientsStandard chemoradiationSTAG2 mutationsTumor clonesPediatric glioblastomaGross total resectionMultiple surgical resectionsTime of recurrenceHigh-grade gliomasDNA damage repair defectsWhole-exome sequencingVariety of treatmentsSurgical resectionNovel deleterious mutationsStandard therapyTotal resectionVaccine therapyClinical evidencePreclinical dataTreatment optionsMultimodal therapyPreclinical studiesClinical settingTherapyAdult counterparts
2014
Thoracic Epidural Teratoma: Case Report and Review of the Literature
Quon JL, Grant RA, Huttner AJ, Duncan CC. Thoracic Epidural Teratoma: Case Report and Review of the Literature. Clinical Pathology 2014, 7: cpath.s14723. PMID: 24940089, PMCID: PMC4055415, DOI: 10.4137/cpath.s14723.Peer-Reviewed Original ResearchSpinal teratomaClinical presentationSevere spinal cord compressionDiagnosis of teratomaSpinal cord compressionGross total resectionSpinal cord tumorsHeterogeneous contrast enhancementSignificant neurologic compromiseClinician's differentialMarked spasticityAmbulatory functionCord compressionCord tumorsTotal resectionNeurologic compromiseEpidural tumorCystic massRare entityCase reportRare subsetMotor milestonesTumorsTeratomaPathophysiology