2014
Neutrophils scan for activated platelets to initiate inflammation
Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nácher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi MD, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A. Neutrophils scan for activated platelets to initiate inflammation. Science 2014, 346: 1234-1238. PMID: 25477463, PMCID: PMC4280847, DOI: 10.1126/science.1256478.Peer-Reviewed Original Research
2013
Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance
Casanova-Acebes M, Pitaval C, Weiss LA, Nombela-Arrieta C, Chèvre R, A-González N, Kunisaki Y, Zhang D, van Rooijen N, Silberstein LE, Weber C, Nagasawa T, Frenette PS, Castrillo A, Hidalgo A. Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance. Cell 2013, 153: 1025-1035. PMID: 23706740, PMCID: PMC4128329, DOI: 10.1016/j.cell.2013.04.040.Peer-Reviewed Original ResearchConceptsBone marrowFunction of neutrophilsNeutrophil clearanceHomeostatic clearanceHematopoietic nicheNeutrophil eliminationHomeostatic signalsAged neutrophilsNeutrophilsRhythmic modulationMarrowCircadian eventsNuclear receptorsHematopoietic progenitorsClearanceInflammationLeukocytesMiceMacrophagesCirculationReceptors