2013
Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance
Casanova-Acebes M, Pitaval C, Weiss LA, Nombela-Arrieta C, Chèvre R, A-González N, Kunisaki Y, Zhang D, van Rooijen N, Silberstein LE, Weber C, Nagasawa T, Frenette PS, Castrillo A, Hidalgo A. Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance. Cell 2013, 153: 1025-1035. PMID: 23706740, PMCID: PMC4128329, DOI: 10.1016/j.cell.2013.04.040.Peer-Reviewed Original ResearchConceptsBone marrowFunction of neutrophilsNeutrophil clearanceHomeostatic clearanceHematopoietic nicheNeutrophil eliminationHomeostatic signalsAged neutrophilsNeutrophilsRhythmic modulationMarrowCircadian eventsNuclear receptorsHematopoietic progenitorsClearanceInflammationLeukocytesMiceMacrophagesCirculationReceptors
2005
CD44 is a physiological E-selectin ligand on neutrophils
Katayama Y, Hidalgo A, Chang J, Peired A, Frenette PS. CD44 is a physiological E-selectin ligand on neutrophils. Journal Of Experimental Medicine 2005, 201: 1183-1189. PMID: 15824084, PMCID: PMC2213157, DOI: 10.1084/jem.20042014.Peer-Reviewed Original ResearchConceptsCell-specific posttranslational modificationsLeukocyte adhesion deficiency type IIPosttranslational modificationsPotential new targetsE-selectinInnate immune responseBroader roleEndothelial cell lineThioglycollate-induced peritonitisP-selectin glycoprotein ligand-1Cell linesNew targetsE-selectin ligandsAdhesion moleculesStaphylococcal enterotoxin ANeutrophil extravasationImmune responseSelectin familyCD44Bone marrowHuman PMNPMN bindInfectious sitesSelectin ligandsSkin pouch