2019
Short-interval intracortical inhibition is decreased in restless legs syndrome across a range of severity
Magalhães S, Queiroz de Paiva J, Kaelin-Lang A, Sterr A, Eckeli A, Winkler A, Fernandes do Prado G, Amaro E, Conforto A. Short-interval intracortical inhibition is decreased in restless legs syndrome across a range of severity. Sleep Medicine 2019, 62: 34-42. PMID: 31539846, DOI: 10.1016/j.sleep.2019.03.021.Peer-Reviewed Original ResearchConceptsShort-interval intracortical inhibitionRLS/WEDCortical thicknessIntracortical inhibitionRestless legs syndrome/Willis-Ekbom diseaseRestless legs syndromePrimary motor cortexWillis-Ekbom diseaseCharacteristic curve analysisGray matter thicknessDiscrimination of participantsIdiopathic mildRange of severityLegs syndromeMotor cortexMagnetic resonance imaging dataMild symptomsSurface-based analysisSeverity ScaleCortical areasMagnetic stimulationWhole brainCurve analysisCharacteristic curveSeverity
2017
Calcium channel blockade with nimodipine reverses MRI evidence of cerebral oedema following acute hypoxia
Rowland M, Ezra M, Winkler A, Garry P, Lamb C, Kelly M, Okell T, Westbrook J, Wise R, Douaud G, Pattinson K. Calcium channel blockade with nimodipine reverses MRI evidence of cerebral oedema following acute hypoxia. Cerebrovascular And Brain Metabolism Reviews 2017, 39: 285-301. PMID: 28857714, PMCID: PMC6360646, DOI: 10.1177/0271678x17726624.Peer-Reviewed Original ResearchConceptsApparent diffusion coefficientAcute hypoxiaAcute cerebral hypoxiaCalcium channel blockadeCalcium channel antagonismSignificant decreaseCalcium channel antagonistsState functional MRIIntracellular calcium fluxBrain responsesGray matter volumeSame brain regionsEffects of hypoxiaCerebral edemaCerebral hypoxiaNeuronal damageMRI evidenceChannel antagonismCytotoxic edemaChannel antagonistsChannel blockadeClinical conditionsMultiparametric MRIMatter volumeWhole brain
2016
Optimal echo time for functional MRI of the infant brain identified in response to noxious stimulation
Goksan S, Hartley C, Hurley S, Winkler A, Duff E, Jenkinson M, Rogers R, Clare S, Slater R. Optimal echo time for functional MRI of the infant brain identified in response to noxious stimulation. Magnetic Resonance In Medicine 2016, 78: 625-631. PMID: 27654315, PMCID: PMC5516146, DOI: 10.1002/mrm.26455.Peer-Reviewed Original Research
2009
Analysis of Genetic Variability and Whole Genome Linkage of Whole-Brain, Subcortical, and Ependymal Hyperintense White Matter Volume
Kochunov P, Glahn D, Winkler A, Duggirala R, Olvera RL, Cole S, Dyer TD, Almasy L, Fox PT, Blangero J. Analysis of Genetic Variability and Whole Genome Linkage of Whole-Brain, Subcortical, and Ependymal Hyperintense White Matter Volume. Stroke 2009, 40: 3685-3690. PMID: 19834011, PMCID: PMC2787844, DOI: 10.1161/strokeaha.109.565390.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAgingBiomarkersBrain IschemiaCerebrospinal Fluid PressureCerebrumChromosome MappingCohort StudiesDisease ProgressionDNA Mutational AnalysisEpendymaFemaleGenetic LinkageGenetic Predisposition to DiseaseGenetic TestingGenetic VariationHumansIntracranial HypertensionLeukoencephalopathiesMagnetic Resonance ImagingMaleMexican AmericansMiddle AgedNerve Fibers, MyelinatedYoung AdultConceptsArterial pulse pressurePulse pressureImportant neuroimaging markerFluid-attenuated inversion recovery imagesCommon risk factorsWhite matter volumeYears of ageInversion recovery imagesHealthy Mexican AmericansHWM volumeFamily Heart StudyRisk factorsCerebral volumeNeuroimaging markerHeart StudyMatter volumeWhite matterWhole brainPathophysiology studiesCerebral integritySan Antonio Family Heart StudyRecovery imagesMexican AmericansWhole-genome linkageGenome linkage