2011
Genetic Architecture of Declarative Memory
Bearden CE, Karlsgodt KH, Bachman P, van Erp TG, Winkler AM, Glahn DC. Genetic Architecture of Declarative Memory. The Neuroscientist 2011, 18: 516-532. PMID: 21832260, PMCID: PMC3545476, DOI: 10.1177/1073858411415113.Peer-Reviewed Original ResearchConceptsGenetic architectureIndependent inheritanceGenetic basisMolecular basisSingle gene disordersMolecular mechanismsGeneralist genesMemory functionHuman memory functionLong-term memoryDistinct aspectsGenesDeclarative memoryCognitive domainsMemory abilityDistinct subcomponentsInheritanceMemoryFunctionIndividual variabilityDomainImportant informationEvidence
2010
A Multimodal Assessment of the Genetic Control over Working Memory
Karlsgodt KH, Kochunov P, Winkler AM, Laird AR, Almasy L, Duggirala R, Olvera RL, Fox PT, Blangero J, Glahn DC. A Multimodal Assessment of the Genetic Control over Working Memory. Journal Of Neuroscience 2010, 30: 8197-8202. PMID: 20554870, PMCID: PMC2894480, DOI: 10.1523/jneurosci.0359-10.2010.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnisotropyBrainBrain MappingDiffusion Magnetic Resonance ImagingFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemory, Short-TermMexican AmericansMiddle AgedNerve Fibers, MyelinatedNeural PathwaysNeuropsychological TestsOxygenPedigreeYoung AdultConceptsMemory performanceComplex cognitive functionsHigher-level processesGray matter densityWorking memoryCognitive measuresResponse taskStructural magnetic resonanceGeneral intelligenceSuperior longitudinal fasciculusHuman participantsWhite matter tractsCognitive functionCognitive deficitsOnly performanceMultimodal assessmentBrain regionsMemoryCommon genetic factorsLongitudinal fasciculusMajor white matter tractsLevel processesMeasuresGray matter regionsCore component