Patients with chronic pain exhibit individually unique cortical signatures of pain encoding
Mayr A, Jahn P, Stankewitz A, Deak B, Winkler A, Witkovsky V, Eren O, Straube A, Schulz E. Patients with chronic pain exhibit individually unique cortical signatures of pain encoding. Human Brain Mapping 2021, 43: 1676-1693. PMID: 34921467, PMCID: PMC8886665, DOI: 10.1002/hbm.25750.Peer-Reviewed Original ResearchConceptsChronic back painEndogenous painAnterior insular cortexBack painChronic painInsular cortexCortical signaturesChronic pain exhibitChronic migraine patientsChange of painIntensity of painFunctional MRI sessionsUnique cortical signaturesChronic migrainePain intensityMigraine patientsPainMultifaceted diseaseClinical observationsPatientsLinear mixed effects modelsFrontal operculumMRI sessionsMixed effects modelsCortical processes