2022
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction
Kember RL, Vickers-Smith R, Xu H, Toikumo S, Niarchou M, Zhou H, Hartwell EE, Crist RC, Rentsch CT, Davis L, Justice A, Sanchez-Roige S, Kampman K, Gelernter J, Kranzler H. Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction. Nature Neuroscience 2022, 25: 1279-1287. PMID: 36171425, PMCID: PMC9682545, DOI: 10.1038/s41593-022-01160-z.Peer-Reviewed Original ResearchConceptsOpioid use disorderGenome-wide association studiesWide significant lociGene expression enrichmentSignificant genetic correlationsCell type groupSignificant lociAssociation studiesExpression enrichmentMillion Veteran ProgramGenetic correlationsUse disordersLociBrain regionsExonic variantsIntronic variantsSubstance use disordersTraitsBiological basisOpioid epidemicPsychiatric disordersVeteran ProgramBrain diseasesTSNARE1FBXW4
2016
Estimating healthcare mobility in the Veterans Affairs Healthcare System
Wang KH, Goulet JL, Carroll CM, Skanderson M, Fodeh S, Erdos J, Womack JA, Abel EA, Bathulapalli H, Justice AC, Nunez-Smith M, Brandt CA. Estimating healthcare mobility in the Veterans Affairs Healthcare System. BMC Health Services Research 2016, 16: 609. PMID: 27769221, PMCID: PMC5075153, DOI: 10.1186/s12913-016-1841-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overDelivery of Health CareElectronic Health RecordsEmigration and ImmigrationFemaleHospitals, VeteransHumansMaleMental DisordersMiddle AgedPatient Acceptance of Health CareRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsVeteransVeterans HealthYoung AdultConceptsHealthcare systemVeterans Health Administration electronic health recordsVeterans Affairs Healthcare SystemHealthcare mobilityRetrospective cohort studyHepatitis C virusOutcomes of careDifferent healthcare systemsDistinct healthcare systemsElectronic health recordsClinical characteristicsCohort studyHealthcare utilizationC virusSpecialty carePsychiatric disordersYounger veteransDisease preventionYounger agePopulation healthHealth recordsVeteransStatus changesCareYear period