2020
All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors
Gordon K, Manhapra A, Crystal S, Dziura J, Edelman E, Skanderson M, Kerns R, Justice A, Tate J, Becker W. All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors. Drug And Alcohol Dependence 2020, 216: 108291. PMID: 33011662, PMCID: PMC7644145, DOI: 10.1016/j.drugalcdep.2020.108291.Peer-Reviewed Original ResearchConceptsMorphine equivalent daily doseCause mortalityLong-term opioid therapyTime-updated Cox regressionStrong dose-response relationshipUnnatural deathsEquivalent daily doseDose-response relationshipOpioid doseOpioid therapyUninfected patientsOpioid useDaily doseCox regressionMortality outcomesTherapy doseHigh doseMale veteransOverdose fatalitiesOverdose mortalityPLWHMortalityHIVPatientsDoseSafety of Gabapentin Prescribed for Any Indication in a Large Clinical Cohort of 571,718 US Veterans with and without Alcohol Use Disorder
Rentsch CT, Morford KL, Fiellin DA, Bryant KJ, Justice AC, Tate JP. Safety of Gabapentin Prescribed for Any Indication in a Large Clinical Cohort of 571,718 US Veterans with and without Alcohol Use Disorder. Alcohol Clinical And Experimental Research 2020, 44: 1807-1815. PMID: 32628784, PMCID: PMC7540277, DOI: 10.1111/acer.14408.Peer-Reviewed Original ResearchConceptsAlcohol use disorderMental statusRelative riskGabapentin exposureUse disordersICD-9 diagnostic codesAdverse neurologic effectsPotential medication interactionsAltered mental statusIncidence of fallsClear dose-response relationshipLarge clinical cohortDose-response relationshipRace/ethnicityUnexposed patientsHepatitis CAdverse eventsMedication interactionsExcess riskNeurologic effectsUS veteransDiagnostic codesIncidence rateClinical cohortHigh risk
2007
Estimating the impact of alcohol consumption on survival for HIV+ individuals
Braithwaite RS, Conigliaro J, Roberts MS, Shechter S, Schaefer A, McGinnis K, Rodriguez MC, Rabeneck L, Bryant K, Justice AC. Estimating the impact of alcohol consumption on survival for HIV+ individuals. AIDS Care 2007, 19: 459-466. PMID: 17453583, PMCID: PMC3460376, DOI: 10.1080/09540120601095734.Peer-Reviewed Original ResearchConceptsAlcohol consumptionFrequency of consumptionDaily consumptionModifiable risk factorsLarge observational cohortHazardous alcohol consumptionDose-response relationshipImpact of alcoholHIV diseaseObservational cohortOverall survivalAntiretroviral adherencePoor outcomeRisk factorsPoor survivalClinical dataHazardous drinkersNonhazardous drinkersAdherence resultsAlcohol's impactSurvivalWeeksDrinkersAdherenceYears
2005
A Temporal and Dose‐Response Association Between Alcohol Consumption and Medication Adherence Among Veterans in Care
Braithwaite RS, McGinnis KA, Conigliaro J, Maisto SA, Crystal S, Day N, Cook RL, Gordon A, Bridges MW, Seiler JF, Justice AC. A Temporal and Dose‐Response Association Between Alcohol Consumption and Medication Adherence Among Veterans in Care. Alcohol Clinical And Experimental Research 2005, 29: 1190-1197. PMID: 16046874, DOI: 10.1097/01.alc.0000171937.87731.28.Peer-Reviewed Original ResearchConceptsAlcohol consumptionDose-response relationshipTime-Line FollowNonbinge drinkersHIV individualsMedication adherencePoor adherenceBinge drinkersDrinking daysVeterans Aging Cohort StudyDose-response associationAging Cohort StudySelf-reported alcohol consumptionTelephone interview surveyCohort studyMedication dosesPrescribed medicationsObservational studyInterview SurveyDrinkersAdherenceSame dayDosesAbstainersCare