Hematologic Immune-Related Adverse Events from Immune Checkpoint Inhibitors: A Systematic Review of Case-Reports and Case-Series
Gnanapandithan K, Kharel P, Grimshaw A, Giri S. Hematologic Immune-Related Adverse Events from Immune Checkpoint Inhibitors: A Systematic Review of Case-Reports and Case-Series. Blood 2019, 134: 3606. DOI: 10.1182/blood-2019-132203.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsAutoimmune hemolytic anemiaPure red cell aplasiaImmune thrombocytopeniaThrombotic thrombocytopenic purpuraCase reportICI therapyIntravenous immunoglobulinHematopoietic growth factorsCheckpoint inhibitorsMost patientsAdverse eventsHemophagocytic lymphohistiocytosisSupportive treatmentCase seriesClinical presentationCommon subtypeTreatment strategiesEligibility criteriaSystematic reviewNon-small cell lung cancerOrgan systemsGrowth factorAnti-thymocyte globulinHigh-dose corticosteroids