2021
Non-steroidal treatment of cardiac sarcoidosis: A systematic review
Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Non-steroidal treatment of cardiac sarcoidosis: A systematic review. IJC Heart & Vasculature 2021, 34: 100782. PMID: 33997256, PMCID: PMC8105294, DOI: 10.1016/j.ijcha.2021.100782.Peer-Reviewed Original ResearchNon-steroidal treatmentSteroid-sparing agentCardiac sarcoidosisSafety profileSystematic reviewCases of CSDisease-modifying antirheumatic agentsManagement of CSActive cardiac sarcoidosisAnti-inflammatory managementAverage corticosteroid doseHigher-line treatmentsMaintenance steroid doseFirst-line treatmentSide effect profileSteroid-sparing therapiesInception of databasesLong-term useCorticosteroid doseSteroid doseBiologic DMARDsImmunosuppressive therapyTreatment initiationEffect profileImmunosuppressive agents
2020
Efficacy and safety of frontline regimens for older transplant-ineligible patients with multiple myeloma: A systematic review and meta-analysis
Giri S, Aryal MR, Yu H, Grimshaw A, Pathak R, Huntington SP, Dhakal B. Efficacy and safety of frontline regimens for older transplant-ineligible patients with multiple myeloma: A systematic review and meta-analysis. Journal Of Geriatric Oncology 2020, 11: 1285-1292. PMID: 32513568, PMCID: PMC8721742, DOI: 10.1016/j.jgo.2020.05.013.Peer-Reviewed Original ResearchConceptsTransplant-ineligible patientsMultiple myelomaTreatment optionsPhase II/IIICumulative ranking (SUCRA) probabilitiesFirst-line treatmentHematopoietic cell transplantationTerms of efficacyRandom-effects modelEfficacious regimensFrailty biomarkersFrontline regimensThalidomide maintenanceEffective regimensGeriatric assessmentLine treatmentTreatment regimensCell transplantationMeeting libraryIndividual patientsToxicity profileRegimensPatientsSystematic reviewRanking probability