2013
Expression of Kv1.3 potassium channels regulates density of cortical interneurons
Duque A, Gazula V, Kaczmarek LK. Expression of Kv1.3 potassium channels regulates density of cortical interneurons. Developmental Neurobiology 2013, 73: 841-855. PMID: 23821603, PMCID: PMC3829632, DOI: 10.1002/dneu.22105.Peer-Reviewed Original ResearchConceptsKv1.3 geneMembrane-spanning channelsKv1.3-/- miceVasoactive intestinal peptideEffect of deletionCerebral cortexKv1.3 potassium channelsNeuropeptide YNeuronal differentiationKv1.3 proteinOlfactory bulbInterneuron populationsSelective poresExpression of Kv1.3Large familyCell membraneKv channelsNumber of calbindinNormal cortical functionWhole cerebral cortexWild-type miceKv1.3GenesDetection of odorsPotassium channels
2012
Selective Functional Interactions between Excitatory and Inhibitory Cortical Neurons and Differential Contribution to Persistent Activity of the Slow Oscillation
Tahvildari B, Wölfel M, Duque A, McCormick DA. Selective Functional Interactions between Excitatory and Inhibitory Cortical Neurons and Differential Contribution to Persistent Activity of the Slow Oscillation. Journal Of Neuroscience 2012, 32: 12165-12179. PMID: 22933799, PMCID: PMC3466092, DOI: 10.1523/jneurosci.1181-12.2012.Peer-Reviewed Original ResearchConceptsInhibitory synaptic potentialsSynaptic potentialsEntorhinal cortexSlow oscillationsCortical neuronal subtypesInhibitory synaptic eventsMouse entorhinal cortexSomatostatin-containing interneuronsVasoactive intestinal peptideInhibitory cortical neuronsAction potential activityCortical pyramidal cellsWhole-cell recordingsRecurrent network activitySubmerged slice preparationPersistent activityExcitatory pyramidalDifferent excitatoryPyramidal neuronsIntestinal peptideNeuropeptide YCortical neuronsPyramidal cellsSlice preparationExcitatory neurons
2007
Morphological characterization of electrophysiologically and immunohistochemically identified basal forebrain cholinergic and neuropeptide Y-containing neurons
Duque A, Tepper JM, Detari L, Ascoli GA, Zaborszky L. Morphological characterization of electrophysiologically and immunohistochemically identified basal forebrain cholinergic and neuropeptide Y-containing neurons. Brain Structure And Function 2007, 212: 55-73. PMID: 17717698, DOI: 10.1007/s00429-007-0143-3.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAnimalsAxonsBasal Nucleus of MeynertBrain MappingCell PolarityCell ShapeCholine O-AcetyltransferaseCholinergic FibersDendritesElectrophysiologyImage CytometryImmunohistochemistryLysineMaleNeural PathwaysNeuronsNeuropeptide YPresynaptic TerminalsRatsRats, Sprague-DawleySoftwareStaining and LabelingConceptsLocal axon collateralsNeuropeptide YBasal forebrainCholinergic neuronsAxon collateralsExtensive local axon collateralsBasal forebrain cholinergicBF cholinergic neuronsLocal axonal arborsCortical slow wavesCortical EEG activityDendritic arborization patternDendritic surface areaDistinct neuronal populationsForebrain cholinergicNPY neuronsBrainstem inputsDendritic thicknessAxonal arborsNeuronal firingArborization patternsSynaptic integrationNeuronal populationsCortical releaseCholinergic
2003
Sleep-wake mechanisms and basal forebrain circuitry.
Zaborszky L, Duque A. Sleep-wake mechanisms and basal forebrain circuitry. Frontiers In Bioscience-Landmark 2003, 8: d1146-69. PMID: 12957822, DOI: 10.2741/1112.Peer-Reviewed Original ResearchConceptsProjection neuronsNeuropeptide YForebrain circuitryCholinergic projection neuronsGABAergic projection neuronsBasal forebrain areasSleep-wake mechanismsSpecific neuronal circuitsSleep-wake statesBasal forebrainForebrain neuronsForebrain areasPutative interneuronsCortical mantleSleep parametersState-related changesVon EconomoCortical activityElectron microscopic identificationNeuronal circuitsSpecific neurotransmittersSleep regulationCognitive functionNeuronsSingle neurons