Featured Publications
Epilepsy Surgery: A Practical Case-Based Approach 2024th Edition
Published by Springer International Publishing, May 2023 DOI 10.1007/978-3-031-23828-4 ISBNs 978-3-03-123827-7, 978-3-03-123828-4Books
2024
Combined neuromodulation and resection for functional cortex epilepsy: a case series.
Merenzon M, Sivaraju A, Herlopian A, Gerrard J, Quraishi I, Hirsch L, Spencer D, Damisah E. Combined neuromodulation and resection for functional cortex epilepsy: a case series. Journal Of Neurosurgery 2024, 1-9. PMID: 38848588, DOI: 10.3171/2024.3.jns24122.Peer-Reviewed Original ResearchMedically refractory epilepsySeizure onset zoneFunctional cortexSeizure outcomeRefractory epilepsyMonths of follow-up dataMaximal safe resectionMedian follow-upTreated with resectionImprove seizure outcomeFocal neuromodulationFollow-up dataPreservation of functionRetrospective analysis of individualsSafe resectionPartial resectionMedian intervalCase seriesPreoperative assessmentSurgical interventionRNS deviceNeurological deficitsNo significant changesResectionRetrospective analysisImproving Clinician Performance in Classifying EEG Patterns on the Ictal-Interictal Injury Continuum Using Interpretable Machine Learning.
Barnett A, Guo Z, Jing J, Ge W, Kaplan P, Kong W, Karakis I, Herlopian A, Jayagopal L, Taraschenko O, Selioutski O, Osman G, Goldenholz D, Rudin C, Westover M. Improving Clinician Performance in Classifying EEG Patterns on the Ictal-Interictal Injury Continuum Using Interpretable Machine Learning. NEJM AI 2024, 1 PMID: 38872809, PMCID: PMC11175595, DOI: 10.1056/aioa2300331.Peer-Reviewed Original ResearchFuture Perspectives
Herlopian A. Future Perspectives. 2024, 947-956. DOI: 10.1007/978-3-031-23828-4_38.Peer-Reviewed Original ResearchMultifocal, Non-lesional Epilepsy
Herlopian A. Multifocal, Non-lesional Epilepsy. 2024, 907-918. DOI: 10.1007/978-3-031-23828-4_36.Peer-Reviewed Original ResearchBilateral Lesional Epilepsy
Herlopian A. Bilateral Lesional Epilepsy. 2024, 819-847. DOI: 10.1007/978-3-031-23828-4_33.Peer-Reviewed Original ResearchNon-dominant, Non-lesional Insular epilepsy
Herlopian A. Non-dominant, Non-lesional Insular epilepsy. 2024, 287-326. DOI: 10.1007/978-3-031-23828-4_13.Peer-Reviewed Original ResearchNon-dominant, Lesional Parieto-occipital Lobe Epilepsy
Herlopian A. Non-dominant, Lesional Parieto-occipital Lobe Epilepsy. 2024, 221-240. DOI: 10.1007/978-3-031-23828-4_11.Peer-Reviewed Original ResearchFocal cortical dysplasiaCortical dysplasiaSupratentorial cystic lesionsPost-operative outcomesInterictal epileptiform activityPredictors of outcomeAnti-seizure medicationsMechanisms of epileptogenesisVisual evoked potentialsNeocortical epilepsy surgeryResection surgeryCystic lesionsSurgical interventionEpileptiform activityDifferential diagnosisEvoked potentialsPharmacoresistant epilepsyPatient populationNeuroimaging characteristicsEpilepsy surgeryDysplasiaPatientsOccipital lobeSensorimotor cortexSurgeryDominant, Tumor-Related Mesial Temporal Lobe Epilepsy
Herlopian A. Dominant, Tumor-Related Mesial Temporal Lobe Epilepsy. 2024, 747-755. DOI: 10.1007/978-3-031-23828-4_30.Peer-Reviewed Original ResearchNon-dominant, Non-lesional Mesial Temporal Lobe Epilepsy
Herlopian A, Mattson R. Non-dominant, Non-lesional Mesial Temporal Lobe Epilepsy. 2024, 63-86. DOI: 10.1007/978-3-031-23828-4_4.Peer-Reviewed Original ResearchTemporal lobe epilepsyLobe epilepsySurgical outcomesMRI-negative temporal lobe epilepsyInterictal PET scanPharmacoresistant temporal lobe epilepsyPost-operative resultsFavorable post-operative resultsTemporal lobe seizuresSlow wave activityMRI-negativePET scansHypermotor symptomsPharmacoresistant epilepsyRespiratory manifestationsNon-lesionalFronto-parietal cortexPatientsEpilepsyImpaired awarenessMultifocal Epilepsy Due to New-Onset Refractory Status Epilepticus
Herlopian A, Gunawardane N. Multifocal Epilepsy Due to New-Onset Refractory Status Epilepticus. 2024, 497-532. DOI: 10.1007/978-3-031-23828-4_21.Peer-Reviewed Original ResearchRefractory status epilepticusStatus epilepticusNew-onset refractory status epilepticusOnset refractory status epilepticusSuper-refractory status epilepticusSingle pulse electrical stimulationCortico-cortical evoked potentialsResponsive neurostimulation deviceNew-onsetMultifocal epilepsySurgical interventionNeuroimaging characteristicsEpilepticusPulse electrical stimulationEpileptic networkEvaluate functional connectivityPatientsCortical stimulationNeurostimulation devicesElectrical stimulationFunctional connectivityLanguage mappingStimulationDominant, Lesional Posterior Quadrant Epilepsy
Herlopian A, Tolba H, Mattson R. Dominant, Lesional Posterior Quadrant Epilepsy. 2024, 757-777. DOI: 10.1007/978-3-031-23828-4_31.Peer-Reviewed Original ResearchIctal high-frequency oscillationsPeriventricular nodular heterotopiaPredicting surgical outcomesSurgical decision-making processFocal cortical dysplasiaPropagation of seizuresInterictal epileptiform dischargesThermoablative therapyNodular heterotopiaSurgical outcomesCortical dysplasiaIctal patternsCortical malformationsEpileptiform dischargesIntracranial monitoringPharmacoresistant epilepsyClonic movementsIctal vocalizationSpeech disturbanceCephalic auraTherapyPatientsHigh-frequency oscillationsAcquired, Lesional Lennox-Gastaut Syndrome
Herlopian A. Acquired, Lesional Lennox-Gastaut Syndrome. 2024, 919-943. DOI: 10.1007/978-3-031-23828-4_37.Peer-Reviewed Original ResearchCentromedian nucleusConfirm electrode placementGeneralized atonic seizuresLennox-Gastaut syndromeCentromedian thalamic nucleusLanguage lateralizationPost-operative language deficitsRare entityLennox-GastautCorpus callosotomySurgical interventionCortical malformationsAtonic seizuresSurgical proceduresThalamic nucleiCorpus callosumEpileptic networkDeep brain stimulation devicesLanguage deficitsNeurostimulation devicesElectrode placementPatientsNeurophysiological recordingsEpilepsyLanguageNon-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex
Herlopian A. Non-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex. 2024, 469-496. DOI: 10.1007/978-3-031-23828-4_20.Peer-Reviewed Original ResearchFocal cortical dysplasiaCortical dysplasiaIntracranial monitoringPredictors of seizure freedomIctal onset patternsPost-operative outcomesSurgical decision-making processFrontal lobe epilepsySensorimotor functionDysplastic cortexResection marginsSurgical interventionSeizure freedomEpileptiform patternsLobe epilepsyPharmacoresistant epilepsyMotor cortexOnset patternsDysplasiaCortexPatientsCircuit organizationEpileptiformEpilepsyDominant, Lesional Congenital Hemispheric Epilepsy
Herlopian A, Mahmud S, Mattson R. Dominant, Lesional Congenital Hemispheric Epilepsy. 2024, 699-731. DOI: 10.1007/978-3-031-23828-4_28.Peer-Reviewed Original ResearchCorpus callosotomyPorencephalic cystPartial frontal lobe resectionGeneralized atonic seizuresAnterior corpus callosotomyFrontal lobe resectionStartle-induced seizuresThalamic hypometabolismAtonic seizuresLobe resectionNeuroimaging findingsHemispheric epilepsyCallosotomyPatientsComplex symptomsSeizuresCystsEpilepsyNon-dominant, Lesional Neocortical Temporal Lobe Epilepsy
Herlopian A. Non-dominant, Lesional Neocortical Temporal Lobe Epilepsy. 2024, 105-134. DOI: 10.1007/978-3-031-23828-4_6.Peer-Reviewed Original ResearchVacuolating neuronal tumorInterictal high-frequency oscillationsDysembryoplastic neuroepithelial tumorEpileptic networkSurgical decision-making processFocal cortical dysplasiaNeuroepithelial tumorsNeuronal tumorsRadiological findingsCortical dysplasiaClinical manifestationsIctal semiologyPharmacoresistant epilepsyDystonic posturingTumorHigh-frequency oscillationsMultifocal Epilepsy and Non-dominant Cingulate Lesion
Herlopian A, Gray T, Quraishi I. Multifocal Epilepsy and Non-dominant Cingulate Lesion. 2024, 393-429. DOI: 10.1007/978-3-031-23828-4_18.Peer-Reviewed Original ResearchMultifocal epilepsyEEG findings of patientsFindings of patientsAnti-seizure medicationsPrognostic roleSurgical outcomesEEG findingsEEG changesCingulate epilepsyHabitual seizuresIctal tachycardiaAnterior cingulate gyrusEpilepsy monitoring unitVascular lesionsIctal speechPredictive valueOutcome determinantsPatientsMonitor unitsCingulate cortexEpilepsyCingulate gyrusCingulateCortexEEGNon-dominant, Non-lesional Orbitofrontal-Plus Epilepsy
Herlopian A. Non-dominant, Non-lesional Orbitofrontal-Plus Epilepsy. 2024, 563-598. DOI: 10.1007/978-3-031-23828-4_23.Peer-Reviewed Original ResearchResection surgeryIntracranial monitoringInterictal PET scanIctal onset patternsPost-operative outcomesNon-lesional epilepsySurgical work-upInterictal epileptiform dischargesNon-invasive modalityDelta slowingEEG findingsInvestigative armamentariumTonic seizuresEpileptiform dischargesPET scansIctal propagationWidespread hypometabolismWork-upInsular epilepsyPsychiatric manifestationsOnset patternsSpike rateEpilepsySurgeryPatientsRasmussen’s Encephalitis and Focal Cortical Dysplasia
Vadiparati A, Herlopian A. Rasmussen’s Encephalitis and Focal Cortical Dysplasia. 2024, 241-286. DOI: 10.1007/978-3-031-23828-4_12.Peer-Reviewed Original ResearchOccipital lobe epilepsyRasmussen encephalitisSurgical interventionLobe epilepsyVisual field analysisSurgical decision-making processFocal cortical dysplasiaLeft occipital lobeAnterior thalamic nucleiClinical presentationCortical dysplasiaMultifocal epilepsySurgical techniqueIntractable seizuresOutcome predictorsDeep brain stimulationThalamic nucleiNeuromodulation therapiesDiagnostic criteriaOccipital lobeOccipital lobectomyProgressive natureEpilepsyBrain stimulationPatientsNon-dominant, Tumor-related Temporal Lobe Epilepsy
Herlopian A. Non-dominant, Tumor-related Temporal Lobe Epilepsy. 2024, 161-174. DOI: 10.1007/978-3-031-23828-4_8.Peer-Reviewed Original ResearchTumor-related epilepsyTumor-related temporal lobe epilepsyPredictor of post-operative outcomesIntra-operative electrocorticographyPost-operative outcomesPre-surgical evaluationTemporal lobe epilepsySurgical approachAdult patientsElectroencephalographic evaluationSemiological differencesMR spectroscopyLobe epilepsyNeuroimaging findingsEpilepsyPatientsLesionsLoss of awareness