Prevalence and Risk Factors of Elevated Pulmonary Artery Pressures in Children With Sickle Cell Disease
Pashankar FD, Carbonella J, Bazzy-Asaad A, Friedman A. Prevalence and Risk Factors of Elevated Pulmonary Artery Pressures in Children With Sickle Cell Disease. Pediatrics 2008, 121: 777-782. PMID: 18381543, DOI: 10.1542/peds.2007-0730.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge DistributionAnemia, Sickle CellChildChild, PreschoolCohort StudiesComorbidityFemaleFollow-Up StudiesHumansHypertension, PulmonaryMaleMass ScreeningPrevalenceProspective StudiesPulmonary Wedge PressureRisk AssessmentSeverity of Illness IndexSex DistributionSurvival AnalysisTricuspid Valve InsufficiencyUltrasonography, Doppler, TranscranialConceptsTricuspid regurgitant jet velocityElevated pulmonary artery pressureElevated tricuspid regurgitant jet velocityPulmonary artery pressureRegurgitant jet velocityTranscranial Doppler examinationArtery pressurePulmonary hypertensionDoppler examinationSickle cell diseaseRisk factorsCell diseaseExact testPeak tricuspid regurgitant jet velocityPulmonary artery systolic pressureHigh pulmonary artery pressureComprehensive clinic visitModerate pulmonary hypertensionRight outflow obstructionAcute chest syndromeMild pulmonary hypertensionPercent of patientsChronic blood transfusionsHigher platelet countsLowest oxygen saturation