UmuD and RecA Directly Modulate the Mutagenic Potential of the Y Family DNA Polymerase DinB
Godoy V, Jarosz D, Simon S, Abyzov A, Ilyin V, Walker G. UmuD and RecA Directly Modulate the Mutagenic Potential of the Y Family DNA Polymerase DinB. Molecular Cell 2007, 28: 1058-1070. PMID: 18158902, PMCID: PMC2265384, DOI: 10.1016/j.molcel.2007.10.025.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBinding SitesBlotting, Far-WesternDNA Polymerase betaDNA-Directed DNA PolymeraseEscherichia coliEscherichia coli ProteinsModels, MolecularMolecular Sequence DataMutagenesisMutationProtein BindingProtein Structure, TertiaryRec A RecombinasesSequence Homology, Amino AcidConceptsRegulatory protein-protein interactionsDNA damage-inducible proteinProtein-protein interactionsY-family DNA polymerasesFamily DNA polymerasesMutagenic phenotypeOpen active siteDinBRecAMutagenic potentialDNA polymeraseFrameshift mutagenesisProteinStructural modelingActive siteEukaryotesOrthologsArchaeaUmuDMutagenesisPolymerasePhenotypeBacteriaSitesEvolution