Regulatory element copy number differences shape primate expression profiles
Iskow RC, Gokcumen O, Abyzov A, Malukiewicz J, Zhu Q, Sukumar AT, Pai AA, Mills RE, Habegger L, Cusanovich DA, Rubel MA, Perry GH, Gerstein M, Stone AC, Gilad Y, Lee C. Regulatory element copy number differences shape primate expression profiles. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 12656-12661. PMID: 22797897, PMCID: PMC3411951, DOI: 10.1073/pnas.1205199109.Peer-Reviewed Original ResearchConceptsCopy number differencesExpression differencesExpression profilesLong intergenic noncoding RNAsCopy numberIntergenic noncoding RNAsGene expression differencesSignificant expression differencesGene expression profilesLevel of RNAUltraconserved elementsRegulatory regionsNoncoding RNAsSelective pressureDifferent genesRegulatory moleculesDevelopmental pathwaysPhenotypic differencesPrimate speciesGenesRNANumber differenceSpeciesExpressionPseudogenes