2019
Treating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study
Gray WA, Cardenas JA, Brodmann M, Werner M, Bernardo NI, George JC, Lansky A. Treating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study. JACC Cardiovascular Interventions 2019, 12: 2375-2384. PMID: 31806218, DOI: 10.1016/j.jcin.2019.08.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationEuropeFemaleFemoral ArteryHumansMaleMiddle AgedPeripheral Arterial DiseasePopliteal ArteryProspective StudiesProsthesis DesignRisk FactorsStentsTime FactorsTreatment OutcomeUnited StatesVascular Access DevicesVascular PatencyVascular System InjuriesConceptsProximal popliteal arteryDrug-coated balloonsSuperficial femoral arteryPlain balloonPopliteal arteryFemoral arteryTack Endovascular SystemLong-term outcomesDCB angioplastyEfficacy endpointPrimary patencyResidual stenosisRestenotic lesionsMulticenter studyFemoropopliteal arteriesEndovascular SystemAngioplastyArteryClassification 2DissectionLesionsBalloonStenosisPatencyPatients
2008
Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis
Kim YH, Dangas GD, Solinas E, Aoki J, Parise H, Kimura M, Franklin-Bond T, Dasgupta NK, Kirtane AJ, Moussa I, Lansky AJ, Collins M, Stone GW, Leon MB, Moses JW, Mehran R. Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis. The American Journal Of Cardiology 2008, 101: 801-806. PMID: 18328844, DOI: 10.1016/j.amjcard.2007.10.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleCoronary AngiographyCoronary StenosisElectrocardiographyFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMyocardial RevascularizationPaclitaxelProspective StudiesSirolimusStentsTreatment OutcomeTubulin ModulatorsUltrasonography, InterventionalConceptsHigh surgical riskMain coronary artery stenosisMajor adverse cardiac eventsUnprotected LMCA stenosisAdverse cardiac eventsCoronary artery stenosisSurgical riskLMCA stenosisCardiac eventsArtery stenosisStent thrombosisMyocardial infarctionBifurcation stenosisUnprotected left main coronary artery stenosisLeft main coronary artery stenosisDrug-eluting stent placementUrgent percutaneous coronary interventionQ-wave myocardial infarctionFeasible therapeutic alternativeOutcomes of patientsPercutaneous coronary interventionPaclitaxel-eluting stentsSingle-stent strategyUnfavorable clinical outcomeSirolimus-eluting stents
2007
Six-Month Clinical and Angiographic Results of a Dedicated Drug-Eluting Stent for the Treatment of Coronary Bifurcation Narrowings
Grube E, Buellesfeld L, Neumann FJ, Verheye S, Abizaid A, McClean D, Mueller R, Lansky A, Mehran R, Costa R, Gerckens U, Trauthen B, Fitzgerald PJ. Six-Month Clinical and Angiographic Results of a Dedicated Drug-Eluting Stent for the Treatment of Coronary Bifurcation Narrowings. The American Journal Of Cardiology 2007, 99: 1691-1697. PMID: 17560877, DOI: 10.1016/j.amjcard.2007.01.043.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntibiotics, AntineoplasticBlood Vessel Prosthesis ImplantationCoronary AngiographyCoronary StenosisCoronary VesselsFemaleHumansMaleMiddle AgedProspective StudiesSirolimusStentsConceptsCoronary bifurcation lesionsBifurcation lesionsDe novo coronary bifurcation lesionsProspective multicenter single-arm studyBiolimus A9-eluting stentMulticenter single-arm studyResult of restenosisTarget lesion revascularizationClinical complication rateSingle-arm studyStent late lossSide branchesDrug-eluting stentsLate stent thrombosisBalloon angioplasty treatmentLesion revascularizationNonbifurcation lesionsAntiplatelet therapyComplication rateAngiographic resultsStent thrombosisBalloon angioplastyPercutaneous interventionAngioplasty treatmentAXXESS stentPercutaneous Coronary Revascularization Using a Trilayer Metal Phosphorylcholine-Coated Zotarolimus-Eluting Stent
Abizaid A, Lansky AJ, Fitzgerald PJ, Tanajura LF, Feres F, Staico R, Mattos L, Abizaid A, Chaves A, Centemero M, Sousa AG, Sousa JE, Zaugg MJ, Schwartz LB. Percutaneous Coronary Revascularization Using a Trilayer Metal Phosphorylcholine-Coated Zotarolimus-Eluting Stent. The American Journal Of Cardiology 2007, 99: 1403-1408. PMID: 17493469, DOI: 10.1016/j.amjcard.2006.12.064.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBlood Vessel Prosthesis ImplantationCardiovascular AgentsCoronary AngiographyCoronary CirculationCoronary RestenosisCoronary StenosisFemaleFollow-Up StudiesHumansMaleMiddle AgedPhosphorylcholineProspective StudiesProsthesis DesignResearch DesignSirolimusStentsTreatment OutcomeTunica IntimaUltrasonography, InterventionalConceptsCoronary artery stenosisQuantitative coronary angiographyZoMaxx stentCoronary angiographyArtery stenosisDe novo coronary artery stenosisSingle-arm prospective clinical trialDevice-deployment success ratesMajor adverse cardiac eventsSegment late lumen lossCoronary occlusive diseaseIntravascular ultrasound resultsNeointimal volume obstructionAdverse cardiac eventsIndependent core laboratoryLate lumen lossNative coronary arteriesPercutaneous coronary revascularizationProspective clinical trialsCoronary stent systemReduction of restenosisCoronary revascularizationVolume obstructionCardiac eventsObstructive lesions
2006
Drug-Eluting and Bare Nitinol Stents for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery: Long-Term Results from the SIROCCO Trial
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Oliva V, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Jaff MR, Mudde C, Tielemans H, Beregi JP. Drug-Eluting and Bare Nitinol Stents for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery: Long-Term Results from the SIROCCO Trial. Journal Of Endovascular Therapy 2006, 13: 701-710. PMID: 17154704, DOI: 10.1583/05-1704.1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlloysAngioplasty, BalloonAnti-Bacterial AgentsAtherosclerosisBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleDouble-Blind MethodDrug CarriersFemaleFemoral ArteryHumansKaplan-Meier EstimateMaleMiddle AgedProspective StudiesProsthesis FailureRecurrenceSafetySirolimusStentsTreatment OutcomeConceptsChronic limb ischemiaAnkle-brachial indexBare stent groupRestenosis rateSirolimus groupLimb ischemiaStent groupSuperficial femoral artery occlusionType C lesionsDouble-blinded studySymptoms of claudicationBare nitinol stentsMajority of patientsSuperficial femoral arteryFemoral artery occlusionStent restenosis rateNitinol self-expanding stentsSelf-expanding stentsTypes of stentsTVR ratesTLR rateArtery occlusionC lesionsClinical outcomesDrug-ElutingPredictors of Recurrent In‐Stent Restenosis after Beta‐Radiation: An Analysis from the START 40/20 Trial
KANEDA H, HONDA Y, MORINO Y, LANSKY AJ, YOCK PG, BONAN R, FITZGERALD PJ. Predictors of Recurrent In‐Stent Restenosis after Beta‐Radiation: An Analysis from the START 40/20 Trial. Journal Of Interventional Cardiology 2006, 19: 376-380. PMID: 17020560, DOI: 10.1111/j.1540-8183.2006.00188.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnalysis of VarianceAngioplasty, Balloon, CoronaryBeta ParticlesBlood Vessel Prosthesis ImplantationBrachytherapyCoronary AngiographyCoronary Artery BypassCoronary RestenosisFemaleFollow-Up StudiesHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesRadiopharmaceuticalsRecurrenceStentsStrontium RadioisotopesTreatment OutcomeUltrasonography, InterventionalYttrium RadioisotopesConceptsTarget lesion revascularizationBalloon/artery ratioLesion revascularizationRecurrent ISRGeographic missArtery ratioStent restenosisPrimary catheter-based interventionMultivariate logistic regression analysisBeta-radiation therapyPredictors of recurrentRecurrence of stenosisTreatment of ISRLarge multicenter trialsMinimum lumen diameterCatheter-based interventionsPreliminary univariate analysisLogistic regression analysisIntravascular ultrasound parametersCohort patientsIndependent predictorsMulticenter trialDiameter stenosisUnivariate analysisBalloon sizingAngiographic Results of the First Human Experience With the Biolimus A9 Drug-Eluting Stent for De Novo Coronary Lesions
Costa RA, Lansky AJ, Abizaid A, Müeller R, Tsuchiya Y, Mori K, Cristea E, Leon MB, Sousa JE, Schmidt T, Hauptmann KE, Grube E. Angiographic Results of the First Human Experience With the Biolimus A9 Drug-Eluting Stent for De Novo Coronary Lesions. The American Journal Of Cardiology 2006, 98: 443-446. PMID: 16893694, DOI: 10.1016/j.amjcard.2006.02.051.Peer-Reviewed Original ResearchMeSH KeywordsBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleCoronary AngiographyCoronary StenosisFeasibility StudiesFollow-Up StudiesHumansImmunosuppressive AgentsProspective StudiesSirolimusStentsTreatment OutcomeConceptsNovo coronary lesionsCoronary lesionsDe novo coronary lesionsNoncomplex coronary lesionsLate lumen lossFirst human experienceDrug-eluting stentsAngiographic characteristicsAngiographic findingsAngiographic resultsLumen lossStent groupBaseline lesionsStent restenosisControl groupLesionsStentsUncoated stentsDistal edgeGroupPatientsHyperplasiaRestenosisOutcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound
Kimura M, Mintz GS, Carlier S, Takebayashi H, Fujii K, Sano K, Yasuda T, Costa RA, Costa JR, Quen J, Tanaka K, Lui J, Weisz G, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Outcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound. The American Journal Of Cardiology 2006, 98: 436-442. PMID: 16893693, DOI: 10.1016/j.amjcard.2006.02.050.Peer-Reviewed Original ResearchConceptsIncomplete stent appositionSES implantationStent appositionSirolimus-eluting stent implantationComplete resolution groupIntravascular ultrasound findingsIncidence of restenosisSerial intravascular ultrasoundConsecutive patientsStent thrombosisStent implantationUltrasound findingsPlaque areaAneurysm formationStent restenosisIntravascular ultrasoundPatientsLumen areaStent strutsGreater decreaseVessel wallThrombosisRestenosisLesionsGreater increaseEffect of Everolimus-Eluting Stents in Different Vessel Sizes (from the Pooled FUTURE I and II Trials)
Tsuchiya Y, Lansky AJ, Costa RA, Mehran R, Pietras C, Shimada Y, Sonoda S, Cristea E, Negoita M, Dangas GD, Moses JW, Leon MB, Fitzgerald PJ, Müller R, Störger H, Hauptmann KE, Grube E. Effect of Everolimus-Eluting Stents in Different Vessel Sizes (from the Pooled FUTURE I and II Trials). The American Journal Of Cardiology 2006, 98: 464-469. PMID: 16893698, DOI: 10.1016/j.amjcard.2006.02.054.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleCoronary AngiographyCoronary RestenosisCoronary VesselsEverolimusFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMiddle AgedProspective StudiesProsthesis DesignSirolimusStentsTreatment OutcomeUltrasonography, InterventionalConceptsBare metal stentsDe novo coronary lesionsNovo coronary lesionsCoronary lesionsNeointimal proliferationStent late lumen lossMid-term outcomesLate lumen lossEverolimus-Eluting StentsQuantitative coronary angiographyMinimum lumen areaVessel sizeII trialCoronary angiographyI trialIncomplete appositionLumen lossStent thrombosisAneurysm formationStent restenosisIntravascular ultrasoundMetal stentsReference diameterLumen areaPatientsTreatment of Coronary Artery Perforations Complicating Percutaneous Coronary Intervention With a Polytetrafluoroethylene-Covered Stent Graft
Lansky AJ, Yang YM, Khan Y, Costa RA, Pietras C, Tsuchiya Y, Cristea E, Collins M, Mehran R, Dangas GD, Moses JW, Leon MB, Stone GW. Treatment of Coronary Artery Perforations Complicating Percutaneous Coronary Intervention With a Polytetrafluoroethylene-Covered Stent Graft. The American Journal Of Cardiology 2006, 98: 370-374. PMID: 16860026, DOI: 10.1016/j.amjcard.2006.02.041.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary stent graftEmergency coronary bypass surgeryQ-wave myocardial infarctionCoronary bypass surgeryCoronary interventionCoronary perforationStent graftBypass surgeryMyocardial infarctionOverall procedure success rateReversal of anticoagulationLife-threatening complicationsCoronary artery perforationProcedure success rateStent-graft implantationAbrupt vessel closureEffective treatment optionProlonged balloon inflationMulticenter seriesCardiogenic shockArtery perforationPericardial tamponadeCardiac arrestTreatment optionsComparative Early and Late Outcomes After Primary Percutaneous Coronary Intervention in ST-Segment Elevation and Non–ST-Segment Elevation Acute Myocardial Infarction (from the CADILLAC Trial)
Cox DA, Stone GW, Grines CL, Stuckey T, Zimetbaum PJ, Tcheng JE, Turco M, Garcia E, Guagliumi G, Iwaoka RS, Mehran R, O’Neill W, Lansky AJ, Griffin JJ, Investigators C. Comparative Early and Late Outcomes After Primary Percutaneous Coronary Intervention in ST-Segment Elevation and Non–ST-Segment Elevation Acute Myocardial Infarction (from the CADILLAC Trial). The American Journal Of Cardiology 2006, 98: 331-337. PMID: 16860018, DOI: 10.1016/j.amjcard.2006.01.102.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalAnticoagulantsBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleElectrocardiographyFemaleFollow-Up StudiesHumansImmunoglobulin Fab FragmentsMaleMiddle AgedMyocardial InfarctionPlatelet Glycoprotein GPIIb-IIIa ComplexStentsStroke VolumeSurvival RateTime FactorsTreatment OutcomeConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionPrimary PCIMyocardial Infarction (TIMI) grade 3 flowIschemic target vessel revascularizationGrade 3 flowOutcomes of patientsTarget vessel revascularizationPercutaneous coronary interventionVessel revascularizationAcute MICoronary interventionMyocardial infarctionAcute ST-segment elevation myocardial infarctionSegment elevation acute myocardial infarctionMajor adverse cardiac eventsElevation acute myocardial infarctionOngoing chest painSimilar late mortalityAdverse cardiac eventsElevation myocardial infarctionST-segment elevationAcute myocardial infarctionHigher ejection fractionPostprocedural Thrombolysis
2005
Bifurcation Coronary Lesions Treated With the “Crush” Technique An Intravascular Ultrasound Analysis
Costa RA, Mintz GS, Carlier SG, Lansky AJ, Moussa I, Fujii K, Takebayashi H, Yasuda T, Costa JR, Tsuchiya Y, Jensen LO, Cristea E, Mehran R, Dangas GD, Iyer S, Collins M, Kreps EM, Colombo A, Stone GW, Leon MB, Moses JW. Bifurcation Coronary Lesions Treated With the “Crush” Technique An Intravascular Ultrasound Analysis. Journal Of The American College Of Cardiology 2005, 46: 599-605. PMID: 16098422, DOI: 10.1016/j.jacc.2005.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryBlood Vessel Prosthesis ImplantationCoronary Artery DiseaseCoronary StenosisDrug Delivery SystemsFemaleHumansMaleMiddle AgedRisk FactorsSirolimusStentsUltrasonography, InterventionalConceptsMinimum stent areaStent areaBifurcation lesionsSB ostiumDistal stentMain vesselCrush areaCrush stent techniqueIntravascular ultrasound findingsHigh restenosis rateSirolimus-eluting stentsBifurcation coronary lesionsIntravascular ultrasound analysisSide branch ostiumIncomplete appositionRestenosis rateCoronary lesionsUltrasound findingsMain lesionIVUS analysisCrush techniqueLesionsOstiumUltrasound analysisBranch ostium
2003
Outcomes of bail-out stenting for suboptimal balloon angioplasty during primary intervention in acute myocardial infarction (The CADILLAC trial)
Ashby DT, Aymong EA, Grines CL, Cox DA, Garcia E, Mehran R, Tcheng JE, Griffin JJ, Guagliumi G, Stuckey T, Carroll JD, Turco M, Lansky AJ, Stone GW. Outcomes of bail-out stenting for suboptimal balloon angioplasty during primary intervention in acute myocardial infarction (The CADILLAC trial). The American Journal Of Cardiology 2003, 92: 1095-1098. PMID: 14583363, DOI: 10.1016/j.amjcard.2003.06.006.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBlood Vessel Prosthesis ImplantationCross-Over StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial InfarctionProspective StudiesStentsTreatment FailureTreatment OutcomeConceptsSuccessful balloon angioplastyAcute myocardial infarctionBalloon angioplastyRoutine stentingMyocardial infarctionEvent-free survivalPrimary balloon angioplastySuboptimal balloon angioplastyCADILLAC trialUnsuccessful dilatationPrimary interventionAngioplastyStentingInfarctionPatientsDilatationTrialsUsefulness of the angiographic pattern of in-stent restenosis in predicting the success of gamma vascular brachytherapy
Costantini CO, Lansky AJ, Mintz GS, Shirai K, Dangas G, Mehran R, Stone GW, Leon MB. Usefulness of the angiographic pattern of in-stent restenosis in predicting the success of gamma vascular brachytherapy. The American Journal Of Cardiology 2003, 92: 1214-1217. PMID: 14609602, DOI: 10.1016/j.amjcard.2003.07.036.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood Vessel Prosthesis ImplantationBrachytherapyCoronary AngiographyFemaleFollow-Up StudiesGamma RaysGraft Occlusion, VascularHumansMaleMiddle AgedPredictive Value of TestsRecurrenceStentsTime FactorsTreatment OutcomeConceptsStent restenosisAngiographic patternsVascular brachytherapyMajor adverse cardiac event ratesAdverse cardiac event ratesBinary angiographic restenosis rateAngiographic restenosis rateCardiac event rateStent restenosis patternsRestenosis patternLesion revascularizationPrognostic roleRestenosis rateTotal occlusionClinical trialsProliferative patternEvent ratesRestenosisPooled data setBrachytherapyRevascularizationPatientsAngiogramsBaselineTrialsComparison of effect of glycoprotein IIb/IIIa inhibitors during percutaneous coronary interventions on risk of hemorrhagic stroke in patients ≥75 years of age versus those <75 years of age
Iakovou I, Dangas G, Mehran R, Mintz GS, Lansky AJ, Aymong ED, Nikolsky E, Vagaonescu T, Glasser LA, Stone GW, Leon MB, Moses JW. Comparison of effect of glycoprotein IIb/IIIa inhibitors during percutaneous coronary interventions on risk of hemorrhagic stroke in patients ≥75 years of age versus those <75 years of age. The American Journal Of Cardiology 2003, 92: 1083-1086. PMID: 14583360, DOI: 10.1016/j.amjcard.2003.07.007.Peer-Reviewed Original ResearchOptimal final lumen area and predictors of target lesion revascularization after stent implantation in small coronary arteries
Iakovou I, Mintz GS, Dangas G, Abizaid A, Mehran R, Lansky AJ, Kobayashi Y, Hirose M, Ashby DT, Stone GW, Moses JW, Leon MB. Optimal final lumen area and predictors of target lesion revascularization after stent implantation in small coronary arteries. The American Journal Of Cardiology 2003, 92: 1171-1176. PMID: 14609591, DOI: 10.1016/j.amjcard.2003.07.025.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationGreater stent expansionSmall coronary arteriesCoronary arteryLesion revascularizationTLR rateStent implantationStent areaSmall vesselsPredictors of TLRAngiographic reference vessel diameterGroup IStent expansionLumen areaHigher TLR rateGroup II patientsBaseline patient characteristicsReference vessel diameterPrior myocardial infarctionEarly clinical eventsReference vessel areaFinal lumen areaHospital outcomesClinical restenosisPatient characteristicsRelation between the degree of procedural anticoagulation and complications after coronary stent implantation
Ashby DT, Dangas G, Aymong EA, Farkouh ME, Mehran R, Lansky AJ, Moses JW, Leon MB, Stone GW. Relation between the degree of procedural anticoagulation and complications after coronary stent implantation. The American Journal Of Cardiology 2003, 92: 319-322. PMID: 12888144, DOI: 10.1016/s0002-9149(03)00637-4.Peer-Reviewed Original Research
2002
Delivered Dose and Vascular Response After β-Radiation for In-Stent Restenosis
Morino Y, Kaneda H, Fox T, Takagi A, Hassan AH, Bonan R, Crocker I, Lansky AJ, Laskey WK, Suntharalingam M, Bonneau HN, Yock PG, Honda Y, Fitzgerald PJ. Delivered Dose and Vascular Response After β-Radiation for In-Stent Restenosis. Circulation 2002, 106: 2334-2339. PMID: 12403663, DOI: 10.1161/01.cir.0000036367.17043.03.Peer-Reviewed Original ResearchMeSH KeywordsBeta ParticlesBlood Vessel Prosthesis ImplantationBrachytherapyCohort StudiesCoronary AngiographyCoronary Artery DiseaseCoronary RestenosisCoronary VesselsDose-Response Relationship, RadiationFemaleHumansLinear ModelsMaleMiddle AgedRadiation DosageRadiometryRetrospective StudiesStentsTreatment OutcomeUltrasonography, InterventionalVascular PatencyConceptsIntimal hyperplasia volumeDose intensityVolumetric intravascular ultrasound analysisDose-dependent complicationsRadiation therapy trialsSerial Volumetric Intravascular Ultrasound AnalysisStent restenosis casesStent restenosis lesionsIn-Stent RestenosisIntravascular ultrasound analysisPrescribed radiation doseSource trainRestenosis casesRestenosis lesionsVascular changesVascular responsesTherapy trialsDose prescriptionLong subsegmentsDevice injuryUltrasound analysisStent segmentDoseDose rangeIVUS catheter7-Hexanoyltaxol–Eluting Stent for Prevention of Neointimal Growth
Kataoka T, Grube E, Honda Y, Morino Y, Hur SH, Bonneau HN, Colombo A, Di Mario C, Guagliumi G, Hauptmann KE, Pitney MR, Lansky AJ, Stertzer SH, Yock PG, Fitzgerald PJ. 7-Hexanoyltaxol–Eluting Stent for Prevention of Neointimal Growth. Circulation 2002, 106: 1788-1793. PMID: 12356631, DOI: 10.1161/01.cir.0000031734.11420.1c.Peer-Reviewed Original ResearchConceptsBare metal stentsNeointimal growthIntravascular ultrasoundDe novo coronary lesionsAdjacent reference segmentsNovo coronary lesionsIndependent core laboratoryHuman feasibility studyNeointimal tissue growthIVUS substudyUnhealed dissectionConventional mechanical treatmentMulticenter trialCoronary lesionsRestenosis rateAtherosclerotic diseaseIntracoronary brachytherapyIVUS analysisNeointimal responseLong-term benefitsNeointimal thickeningStented segmentsCore laboratoryMetal stentsReference segmentsLate Vascular Response to Repeat Stenting for In-Stent Restenosis With and Without Radiation
Morino Y, Limpijankit T, Honda Y, Lansky AJ, Waksman R, Bonneau HN, Yock PG, Mintz GS, Fitzgerald PJ. Late Vascular Response to Repeat Stenting for In-Stent Restenosis With and Without Radiation. Circulation 2002, 105: 2465-2468. PMID: 12034650, DOI: 10.1161/01.cir.0000018949.39445.40.Peer-Reviewed Original ResearchMeSH KeywordsBlood Vessel Prosthesis ImplantationBrachytherapyCohort StudiesCoronary RestenosisDisease ProgressionDouble-Blind MethodFollow-Up StudiesGamma RaysHumansIridium RadioisotopesPlatelet Aggregation InhibitorsRandomized Controlled Trials as TopicRecurrenceReoperationStentsTiclopidineTimeTreatment OutcomeUltrasonography, InterventionalVascular PatencyConceptsLumen volume indexISR lesionsPlacebo patientsLate vascular responseAcute angiographic resultsIntravascular ultrasound analysisIn-Stent RestenosisPlacebo groupAngiographic resultsVascular responsesAdditional lumenNeointimal proliferationStent restenosisIrradiated groupPatientsStent overlapLesionsVolume indexUltrasound analysisSafety of radiationLong-term advantagesStent strutsSignificant decreaseStentingRestenosis