2022
Intravascular Imaging for Guiding In‐Stent Restenosis and Stent Thrombosis Therapy
Erdogan E, Bajaj R, Lansky A, Mathur A, Baumbach A, Bourantas C. Intravascular Imaging for Guiding In‐Stent Restenosis and Stent Thrombosis Therapy. Journal Of The American Heart Association 2022, 11: e026492. PMID: 36326067, PMCID: PMC9750080, DOI: 10.1161/jaha.122.026492.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary interventionStent failureStent restenosisStent thrombosisSecond-generation drug-eluting stentsConventional percutaneous coronary interventionHigh-risk patientsBetter clinical outcomesLong-term outcomesDrug-eluting stentsCumulative incidenceClinical outcomesWorse prognosisProcedural resultsComplex anatomyEndovascular devicesRestenosisTherapyStent technologyDrug kineticsIntravascular imagingTreatment planningNeointima tissueThrombosis
2009
5-Year Clinical Outcomes After Sirolimus-Eluting Stent Implantation Insights From a Patient-Level Pooled Analysis of 4 Randomized Trials Comparing Sirolimus-Eluting Stents With Bare-Metal Stents
Caixeta A, Leon MB, Lansky AJ, Nikolsky E, Aoki J, Moses JW, Schofer J, Morice MC, Schampaert E, Kirtane AJ, Popma JJ, Parise H, Fahy M, Mehran R. 5-Year Clinical Outcomes After Sirolimus-Eluting Stent Implantation Insights From a Patient-Level Pooled Analysis of 4 Randomized Trials Comparing Sirolimus-Eluting Stents With Bare-Metal Stents. Journal Of The American College Of Cardiology 2009, 54: 894-902. PMID: 19712798, DOI: 10.1016/j.jacc.2009.04.077.Peer-Reviewed Original ResearchConceptsBare metal stentsTarget vessel revascularizationStent thrombosisRate of deathMyocardial infarctionVessel revascularizationPooled analysisAcademic Research Consortium definitionsPatient-level pooled analysisDrug-eluting stent implantationArterial healing responseComposite of deathProbable stent thrombosisLong-term safetyDrug-eluting stentsLate stent thrombosisClinical outcomesRandomized trialsStent implantationSuperior efficacyBMS groupThrombosisHealing responseSES groupStentsA Volumetric Intravascular Ultrasound Comparison of Early Drug-Eluting Stent Thrombosis Versus Restenosis
Liu X, Doi H, Maehara A, Mintz GS, de Ribamar Costa J, Sano K, Weisz G, Dangas GD, Lansky AJ, Kreps EM, Collins M, Fahy M, Stone GW, Moses JW, Leon MB, Mehran R. A Volumetric Intravascular Ultrasound Comparison of Early Drug-Eluting Stent Thrombosis Versus Restenosis. JACC Cardiovascular Interventions 2009, 2: 428-434. PMID: 19463466, DOI: 10.1016/j.jcin.2009.01.011.Peer-Reviewed Original ResearchConceptsStent thrombosis groupIntravascular ultrasound findingsMinimum stent areaStent areaThrombosis groupISR groupStent thrombosisUltrasound findingsIntravascular Ultrasound ComparisonProximal stent segmentISR patientsDES thrombosisEdge dissectionStent underexpansionUltrasound comparisonStent fractureThrombosis patientsEarlier drugsStent restenosisThrombosisPatientsStent expansionStent segmentRestenosisLesions
2006
Outcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound
Kimura M, Mintz GS, Carlier S, Takebayashi H, Fujii K, Sano K, Yasuda T, Costa RA, Costa JR, Quen J, Tanaka K, Lui J, Weisz G, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Outcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound. The American Journal Of Cardiology 2006, 98: 436-442. PMID: 16893693, DOI: 10.1016/j.amjcard.2006.02.050.Peer-Reviewed Original ResearchConceptsIncomplete stent appositionSES implantationStent appositionSirolimus-eluting stent implantationComplete resolution groupIntravascular ultrasound findingsIncidence of restenosisSerial intravascular ultrasoundConsecutive patientsStent thrombosisStent implantationUltrasound findingsPlaque areaAneurysm formationStent restenosisIntravascular ultrasoundPatientsLumen areaStent strutsGreater decreaseVessel wallThrombosisRestenosisLesionsGreater increase
2005
Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation An intravascular ultrasound study
Fujii K, Carlier SG, Mintz GS, Yang YM, Moussa I, Weisz G, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation An intravascular ultrasound study. Journal Of The American College Of Cardiology 2005, 45: 995-998. PMID: 15808753, DOI: 10.1016/j.jacc.2004.12.066.Peer-Reviewed Original ResearchConceptsSirolimus-eluting stent implantationMinimum stent cross-sectional areaSuccessful SES implantationStent thrombosisSegment stenosisStent thrombosis groupStent underexpansionSES implantationThrombosis groupControl patientsStent implantationStent cross-sectional areaIntravascular ultrasound studyIndependent predictorsUltrasound studyThrombosisDrug AdministrationControl groupNumber of casesStenosisStent expansionPatientsU.S. FoodUnderexpansionCross-sectional area
2003
Long-term follow-up of patients after gamma intracoronary brachytherapy failure (from GAMMA-I, GAMMA-II, and SCRIPPS-III)
Limpijankit T, Mehran R, Mintz GS, Dangas G, Lansky AJ, Kao J, Ashby DT, Moussa I, Stone GW, Moses JW, Leon MB, Teirstein PS. Long-term follow-up of patients after gamma intracoronary brachytherapy failure (from GAMMA-I, GAMMA-II, and SCRIPPS-III). The American Journal Of Cardiology 2003, 92: 315-318. PMID: 12888143, DOI: 10.1016/s0002-9149(03)00636-2.Peer-Reviewed Original ResearchConceptsAdverse eventsCoronary Artery Bypass GraftingTotal adverse eventsArtery Bypass GraftingCoronary artery bypassFirst-line therapyPercutaneous coronary interventionLong-term outcomesBrachytherapy failureArtery bypassBypass GraftingVessel revascularizationCoronary interventionIndependent predictorsMyocardial infarctionRadiation failureStent restenosisLate thrombosisPatientsTherapyBrachytherapyRevascularizationInfarctionThrombosisFailurePredictors and sequalae of subacute thrombosis after percutaneous intervention in acute myocardial infarction: The CADILLAC trial
Aymong E, Grines C, Cox D, Garcia E, Tcheng J, Griffin J, Guagliumi G, Stuckey T, Turco M, Carroll J, Rutherford B, Lansky A, Mehran R, Stone G. Predictors and sequalae of subacute thrombosis after percutaneous intervention in acute myocardial infarction: The CADILLAC trial. Journal Of The American College Of Cardiology 2003, 41: 393. DOI: 10.1016/s0735-1097(03)81130-0.Peer-Reviewed Original Research
2002
Prolonged antiplatelet therapy and reduced stenting eliminates late thrombosis after radiation: the SCRIPPS III trial
Teirstein P, Moses J, Leon M, Casterella P, Reilly J, Glap H, Jani S, Balter S, Tripuraneni P, Lansky A, Negoita M, Mehran R. Prolonged antiplatelet therapy and reduced stenting eliminates late thrombosis after radiation: the SCRIPPS III trial. Journal Of The American College Of Cardiology 2002, 39: 65. DOI: 10.1016/s0735-1097(02)80281-9.Peer-Reviewed Original Research
2001
Combination therapy with aspirin plus clopidogrel versus aspirin plus ticlopidine for prevention of subacute thrombosis after successful native coronary stenting
Dangas G, Mehran R, Abizaid A, Curry B, Lansky A, Kent K, Pichard A, Satler L, Paliou M, Stone G, Leon M. Combination therapy with aspirin plus clopidogrel versus aspirin plus ticlopidine for prevention of subacute thrombosis after successful native coronary stenting. The American Journal Of Cardiology 2001, 87: 470-472. PMID: 11179539, DOI: 10.1016/s0002-9149(00)01408-9.Peer-Reviewed Original Research