Featured Publications
Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study
Hajduk AM, Saczynski JS, Tsang S, Geda ME, Dodson JA, Ouellet GM, Goldberg RJ, Chaudhry SI. Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study. The American Journal Of Medicine 2021, 134: 910-917. PMID: 33737057, PMCID: PMC8243828, DOI: 10.1016/j.amjmed.2021.03.003.Peer-Reviewed Original ResearchConceptsSevere cognitive impairmentAcute myocardial infarctionMyocardial infarctionCognitive impairmentOlder acute myocardial infarction patientsCognitive statusMultivariable-adjusted logistic regressionAcute myocardial infarction patientsOlder adultsRoutine cognitive screeningRisk of readmissionMedical record reviewRisk of deathPost-discharge periodMyocardial infarction patientsMyocardial infarction survivorsSILVER-AMI StudyComorbidity burdenHospital readmissionPoor outcomeRecord reviewFunctional statusInfarction patientsUnadjusted analysesInfarction survivorsPredicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study.
Dodson JA, Hajduk AM, Geda M, Krumholz HM, Murphy TE, Tsang S, Tinetti ME, Nanna MG, McNamara R, Gill TM, Chaudhry SI. Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. Annals Of Internal Medicine 2019, 172: 12-21. PMID: 31816630, PMCID: PMC7695040, DOI: 10.7326/m19-0974.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPost-AMI mortalityFunctional impairmentOlder adultsCohort studyMean ageMyocardial infarctionPatient-reported health statusNet reclassification improvement indexProspective cohort studyParticipants' mean ageFinal risk modelMobility impairmentsGood discriminatory abilityRisk modelChart reviewHospital dischargePrognostic utilityBlood InstituteClinical variablesNational HeartHigh prevalenceHealth statusMortalityYounger counterpartsRisk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study
Hajduk AM, Dodson JA, Murphy TE, Tsang S, Geda M, Ouellet GM, Gill TM, Brush JE, Chaudhry SI. Risk Model for Decline in Activities of Daily Living Among Older Adults Hospitalized With Acute Myocardial Infarction: The SILVER‐AMI Study. Journal Of The American Heart Association 2020, 9: e015555. PMID: 33000681, PMCID: PMC7792390, DOI: 10.1161/jaha.119.015555.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionDaily living declineSILVER-AMI StudyDaily livingOlder patientsMonths postdischargeMyocardial infarctionFunctional declineImportant patient-centered outcomesPoor long-term outcomesLonger hospital stayLong-term outcomesPatient-centered outcomesGeriatric impairmentsHospital stayAMI survivorsClinical variablesMean ageMedical recordsRisk factorsRestorative therapyPhysical activityAMI hospitalizationPsychosocial factorsUS hospitalsAssociation Between Mobility Measured During Hospitalization and Functional Outcomes in Older Adults With Acute Myocardial Infarction in the SILVER-AMI Study
Hajduk AM, Murphy TE, Geda ME, Dodson JA, Tsang S, Haghighat L, Tinetti ME, Gill TM, Chaudhry SI. Association Between Mobility Measured During Hospitalization and Functional Outcomes in Older Adults With Acute Myocardial Infarction in the SILVER-AMI Study. JAMA Internal Medicine 2019, 179: 1669-1677. PMID: 31589285, PMCID: PMC6784755, DOI: 10.1001/jamainternmed.2019.4114.Peer-Reviewed Original ResearchAcute myocardial infarctionFunctional declineModerate impairmentMild impairmentSevere impairmentOlder patientsADL declineMyocardial infarctionRisk markersMobility impairmentsOlder survivorsAMI hospitalizationMultivariable-adjusted logistic regressionImportant patient-centered outcomesOlder adultsProspective cohort studyPatient-centered outcomesSelf-reported functionSILVER-AMI StudyPotent risk markerPercent of participantsCohort studyPrimary outcomeMean ageFunctional outcome
2023
Sex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction
Brush J, Chaudhry S, Dreyer R, D'Onofrio G, Greene E, Hajduk A, Lu Y, Krumholz H. Sex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction. The American Journal Of Cardiology 2023, 197: 101-107. PMID: 37062667, PMCID: PMC10198892, DOI: 10.1016/j.amjcard.2023.03.009.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionD2B timeSymptom complexityYoung womenChest painBalloon timeST-elevation myocardial infarctionSILVER-AMI StudySymptom phenotypeSex differencesPain symptomsCoronary interventionOlder patientsMyocardial infarctionOlder womenSTEMIOlder menSymptom patternsPresentation delayPatientsSymptom clustersLogistic regressionSymptomsWomenMean number
2022
A risk model for decline in health status after acute myocardial infarction among older adults
Hajduk A, Dodson J, Murphy T, Chaudhry S. A risk model for decline in health status after acute myocardial infarction among older adults. Journal Of The American Geriatrics Society 2022, 71: 1228-1235. PMID: 36519774, PMCID: PMC10089939, DOI: 10.1111/jgs.18162.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHealth status declineImportant patient-centered outcomesPatient-centered outcomesMyocardial infarctionStatus declineHealth statusOlder adultsShort Form-12 Physical Component ScorePhysical component scoreProspective cohort studyRisk prediction modelLogistic regression modelsOlder adult survivorsPredictive risk modelRisk modelCohort studyPatient ageValidation cohortC-statisticRisk factorsHigh riskLower riskAdult survivorsHospitalizationRacial disparities among older adults with acute myocardial infarction: The SILVER‐AMI study
Demkowicz P, Hajduk A, Dodson J, Oladele C, Chaudhry S. Racial disparities among older adults with acute myocardial infarction: The SILVER‐AMI study. Journal Of The American Geriatrics Society 2022, 71: 474-483. PMID: 36415964, PMCID: PMC9957871, DOI: 10.1111/jgs.18084.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionFunctional impairmentGeriatric conditionsClinical characteristicsMyocardial infarctionBlack participantsOlder adultsRacial disparitiesRisk of mortalityMore functional impairmentSILVER-AMI StudyBlack older adultsYounger average ageUnadjusted oddsDaily livingAMI hospitalizationAverage ageGeriatric phenotypesUS hospitalsHospitalizationLogistic regressionMortalityImpairmentInfarctionUnintentional lossAssociation of Financial Strain With Mortality Among Older US Adults Recovering From an Acute Myocardial Infarction
Falvey JR, Hajduk AM, Keys CR, Chaudhry SI. Association of Financial Strain With Mortality Among Older US Adults Recovering From an Acute Myocardial Infarction. JAMA Internal Medicine 2022, 182: 445-448. PMID: 35188537, PMCID: PMC8861896, DOI: 10.1001/jamainternmed.2021.8569.Peer-Reviewed Original Research
2020
Changes in Functional Status and Health-Related Quality of Life in Older Adults After Surgical, Interventional, or Medical Management of Acute Myocardial Infarction
Mori M, Djulbegovic M, Hajduk A, Holland ML, Krumholz HM, Chaudhry SI. Changes in Functional Status and Health-Related Quality of Life in Older Adults After Surgical, Interventional, or Medical Management of Acute Myocardial Infarction. Seminars In Thoracic And Cardiovascular Surgery 2020, 33: 72-81. PMID: 32439546, PMCID: PMC7983308, DOI: 10.1053/j.semtcvs.2020.05.001.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graftPercutaneous coronary interventionAcute myocardial infarctionPhysical component scaleMedical managementFunctional statusOlder patientsMyocardial infarctionArtery bypass graftHealth-related qualityAge 75 yearsPatient-centered outcomesRisk of declinePredictors of declineQuality of lifeUnadjusted incidenceCoronary interventionADL declineCardiac surgeryMedical therapyBypass graftSF-12Multivariable modelHRQoLPatients
2018
COGNITIVE IMPAIRMENT AND SIX-MONTH OUTCOMES AMONG OLDER ADULTS WITH MYOCARDIAL INFARCTION: THE SILVER-AMI STUDY
Hajduk A, Saczynski J, Tsang S, Geda M, Dodson J, Ouellet G, Goldberg R, Chaudhry S. COGNITIVE IMPAIRMENT AND SIX-MONTH OUTCOMES AMONG OLDER ADULTS WITH MYOCARDIAL INFARCTION: THE SILVER-AMI STUDY. Innovation In Aging 2018, 2: 772-772. PMCID: PMC6228403, DOI: 10.1093/geroni/igy023.2857.Peer-Reviewed Original ResearchAcute myocardial infarctionSevere cognitive impairmentCognitive impairmentHospital readmissionAMI survivorsPoor outcomeMyocardial infarctionOlder adultsElderly AMI survivorsMedical record reviewRate of readmissionRisk of readmissionSix-month outcomesRisk of deathSILVER-AMI StudyAMI typeComorbidity burdenPatient ageRecord reviewUnadjusted analysesFunctional statusReadmissionSignificant associationCognitive statusCognitive screening