2011
Serum Human Epididymis Protein 4 and Risk for Ovarian Malignancy Algorithm as New Diagnostic and Prognostic Tools for Epithelial Ovarian Cancer Management
Bandiera E, Romani C, Specchia C, Zanotti L, Galli C, Ruggeri G, Tognon G, Bignotti E, Tassi RA, Odicino F, Caimi L, Sartori E, Santin AD, Pecorelli S, Ravaggi A. Serum Human Epididymis Protein 4 and Risk for Ovarian Malignancy Algorithm as New Diagnostic and Prognostic Tools for Epithelial Ovarian Cancer Management. Cancer Epidemiology Biomarkers & Prevention 2011, 20: 2496-2506. PMID: 22028406, PMCID: PMC3237732, DOI: 10.1158/1055-9965.epi-11-0635.Peer-Reviewed Original ResearchConceptsHuman epididymis protein 4Epithelial ovarian cancerSerum human epididymis protein 4Independent prognostic factorOvarian Malignancy AlgorithmPrognostic factorsMalignancy AlgorithmProgression-free survivalLymph node involvementOvarian cancer managementPreoperative serum samplesProtein 4Ovarian benign cystsElevated CA125Node involvementPositive cytologyPostmenopausal womenPremenopausal womenMultivariable analysisMulticenter studyPrognostic valueAdvanced ageOvarian cancerBenign cystsObstetricians stage
2008
Claudin‐7 expression in human epithelial ovarian cancer
TASSI RA, BIGNOTTI E, FALCHETTI M, RAVANINI M, CALZA S, RAVAGGI A, BANDIERA E, FACCHETTI F, PECORELLI S, SANTIN AD. Claudin‐7 expression in human epithelial ovarian cancer. International Journal Of Gynecological Cancer 2008, 18: 1262-1271. PMID: 18298564, DOI: 10.1111/j.1525-1438.2008.01194.x.Peer-Reviewed Original ResearchConceptsEpithelial ovarian carcinomaHistologic typeClaudin-7 expressionClaudin-7Ovarian carcinomaOvarian cancerPeritoneal cavityEOC cellsMetastatic epithelial ovarian carcinomaHuman epithelial ovarian cancerCLDN-7 expressionMain histologic typesEpithelial ovarian cancerProtein levelsGrade of differentiationReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionTight junction proteinsNovel diagnostic markerEpithelium cell lineSingle neoplastic cellsHuman normal tissuesPleural effusionPathologic stageInflammatory cells
2004
Increased levels of gangliosides in the plasma and ascitic fluid of patients with advanced ovarian cancer
Santin AD, Ravindranath MH, Bellone S, Muthugounder S, Palmieri M, O'Brien TJ, Roman J, Cannon MJ, Pecorelli S. Increased levels of gangliosides in the plasma and ascitic fluid of patients with advanced ovarian cancer. BJOG An International Journal Of Obstetrics & Gynaecology 2004, 111: 613-618. PMID: 15198791, DOI: 10.1111/j.1471-0528.2004.00142.x.Peer-Reviewed Original ResearchConceptsOvarian cancer patientsAdvanced ovarian cancerAdvanced ovarian cancer patientsNormal female controlsPrimary ovarian cancer cell linesOvarian cancer cell linesCancer patientsCancer cell linesOvarian cancerTotal gangliosidesFemale controlsAscitic fluidUterine carcinoma cell linesCell linesJohn Wayne Cancer InstituteAnti-tumor immune functionGanglioside levelsUterine cancer cell linesLipid-associated sialic acidTotal ganglioside levelsTime of surgeryDepartment of ObstetricsPrimary cervical cancerPrimary ovarian tumorsOvarian tumor cells