Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival
Wenzel L, Osann K, McKinney C, Cella D, Fulci G, Scroggins MJ, Lankes HA, Wang V, Nephew KP, Maxwell GL, Mok SC, Conrads TP, Miller A, Mannel RS, Gray HJ, Hanjani P, Huh WK, Spirtos N, Leitao MM, Glaser G, Sharma SK, Santin AD, Sperduto P, Lele SB, Burger RA, Monk BJ, Birrer M. Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival. Journal Of The National Cancer Institute 2021, 113: 1369-1378. PMID: 33729494, PMCID: PMC8486331, DOI: 10.1093/jnci/djab034.Peer-Reviewed Original ResearchConceptsLong-term survivorsShort-term survivorsQuality of lifeOvarian cancer survivalLong-term survivalAdverse eventsCancer survivalBaseline QOLCancer Therapy-OvarianTrial Outcome IndexMeaningful prognostic valueLongitudinal mixed modelsAE gradeRobust prognosticatorPatient characteristicsPrognostic valueQoL changesSurvivor groupGOG 218Prognostic relationshipOutcome indexTrial designFunctional assessmentCare implicationsChange scores