Low Expression of Claudin-7 as Potential Predictor of Distant Metastases in High-Grade Serous Ovarian Carcinoma Patients
Romani C, Zizioli V, Silvestri M, Ardighieri L, Bugatti M, Corsini M, Todeschini P, Marchini S, D'Incalci M, Zanotti L, Ravaggi A, Facchetti F, Gambino A, Odicino F, Sartori E, Santin AD, Mitola S, Bignotti E, Calza S. Low Expression of Claudin-7 as Potential Predictor of Distant Metastases in High-Grade Serous Ovarian Carcinoma Patients. Frontiers In Oncology 2020, 10: 1287. PMID: 32850397, PMCID: PMC7417514, DOI: 10.3389/fonc.2020.01287.Peer-Reviewed Original ResearchHigh-grade serous ovarian carcinomaDistant metastasisClaudin-7High-grade serous ovarian carcinoma patientsSerous ovarian carcinoma patientsClaudin-3Distant hematogenous metastasisDistant metastatic eventsNormal tubal epitheliumSite of metastasisOvarian carcinoma patientsSerous ovarian carcinomaFallopian tube epitheliumExpression levelsNormal fallopian tube epitheliumTight junction proteinsExpression of claudinsHematogenous recurrenceRoutes of disseminationQuantitative RT-PCRDistant diseaseHematogenous routeCarcinoma patientsClinicopathological featuresHGSOC patients