Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy
Santin AD, Zhan F, Bignotti E, Siegel ER, Cané S, Bellone S, Palmieri M, Anfossi S, Thomas M, Burnett A, Kay HH, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J, Pecorelli S. Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy. Virology 2005, 331: 269-291. PMID: 15629771, DOI: 10.1016/j.virol.2004.09.045.Peer-Reviewed Original ResearchConceptsTissue factor pathway inhibitor-2Normal cervical keratinocytesCDKN2A/p16V-myb myeloblastosis viral oncogene homologDifferential expressionMyeloblastosis viral oncogene homologE2F transcription factor 1Cyclin-dependent kinase inhibitor 2AGene expression profilesMesoderm-specific transcriptNovel candidate molecular markersNovel molecular featuresGene expression dataQuantitative real-time PCRSerine proteinase inhibitorTranscription factor 1V-mybDUTP pyrophosphataseProstaglandin E synthaseTopoisomerase II alphaCandidate molecular markersForkhead box M1Growth factor alphaOligonucleotide microarraysExpression profiles