2000
Severe regional ischemia alters coronary flow reserve in the remote perfusion area
Wu J, Yun J, Dione D, Heller E, Deckelbaum L, Sinusas A. Severe regional ischemia alters coronary flow reserve in the remote perfusion area. Journal Of Nuclear Cardiology 2000, 7: 43-52. PMID: 10698234, DOI: 10.1067/mnc.2000.99189.Peer-Reviewed Original ResearchConceptsLAD coronary flow reserveCoronary flow reserveLCX stenosisFlow reserveImpairment of CFRStenosis severityRemote nonischemic regionsRate-pressure productRegional myocardial dysfunctionDoppler flow probesTransstenotic pressure gradientOpen-chest dogsAcute canine modelIschemic dysfunctionAnterior descendingIntracoronary injectionMyocardial dysfunctionProximal LCXCoronary stenosisMyocardial infarctionAcute ischemiaProgressive impairmentPerfusion areaRegional myocardial flowTransstenotic gradient
1995
962-67 Dobutamine Stress has a Limited Value for Enhancing Flow Heterogeneity in the Presence of a Moderate Stenosis When Used in Conjunction with Tc99m-Sestamibi Imaging
Yun J, Wu J, Heller E, Deckelbaum L, Dione D, Liu Y, Wackers F, Sinusas A. 962-67 Dobutamine Stress has a Limited Value for Enhancing Flow Heterogeneity in the Presence of a Moderate Stenosis When Used in Conjunction with Tc99m-Sestamibi Imaging. Journal Of The American College Of Cardiology 1995, 25: 217a. DOI: 10.1016/0735-1097(95)92360-h.Peer-Reviewed Original ResearchMB activityModerate stenosisDOB stressMean aortic pressureOpen-chest dogsSPECT perfusion imagingLCX stenosisProximal LCXPeak dobutamineAortic pressureDobutamine stressMB injectionChest dogsHeart rateNonischemicStenosisDobutamineIschemic regionPerfusion imagingFlow probeRadiolabeled microspheresFlow deficitsMicrosphere flowLimited valueBaseline