2000
Severe regional ischemia alters coronary flow reserve in the remote perfusion area
Wu J, Yun J, Dione D, Heller E, Deckelbaum L, Sinusas A. Severe regional ischemia alters coronary flow reserve in the remote perfusion area. Journal Of Nuclear Cardiology 2000, 7: 43-52. PMID: 10698234, DOI: 10.1067/mnc.2000.99189.Peer-Reviewed Original ResearchConceptsLAD coronary flow reserveCoronary flow reserveLCX stenosisFlow reserveImpairment of CFRStenosis severityRemote nonischemic regionsRate-pressure productRegional myocardial dysfunctionDoppler flow probesTransstenotic pressure gradientOpen-chest dogsAcute canine modelIschemic dysfunctionAnterior descendingIntracoronary injectionMyocardial dysfunctionProximal LCXCoronary stenosisMyocardial infarctionAcute ischemiaProgressive impairmentPerfusion areaRegional myocardial flowTransstenotic gradient
1990
Cardiac imaging with technetium 99m-labeled isonitriles
Sinusas A, Beller G, Watson D. Cardiac imaging with technetium 99m-labeled isonitriles. Journal Of Thoracic Imaging 1990, 5: 20-30. PMID: 2194038, DOI: 10.1097/00005382-199007000-00006.Peer-Reviewed Original ResearchConceptsMyocardial perfusionMyocardial injuryMyocardial ischemiaNoninvasive meansAcute coronary occlusionIschemic myocardial injuryIrreversible myocardial injurySingle-day protocolFull clinical implicationsFurther clinical studiesReversible myocardial ischemiaMyocardial dysfunctionMyocardial salvageCoronary occlusionClinical studiesMyocardial imaging agentClinical experienceTherapeutic interventionsInitial experienceClinical implicationsPerfusionIschemiaImaging agentInjuryRadiotracer