Links Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes
Aneni E, Sinusas A, Emokpae M, Thorn S, Yaggi H, Miller E. Links Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes. Current Cardiology Reports 2024, 26: 723-734. PMID: 38806976, DOI: 10.1007/s11886-024-02072-z.Peer-Reviewed Original ResearchObstructive sleep apneaCoronary microvascular dysfunctionAbnormal myocardial blood flowSevere obstructive sleep apneaMyocardial flow reserveMyocardial blood flowSleep apneaModerate to severe obstructive sleep apneaAbnormal myocardial flow reserveRecent FindingsRecent studiesDisease-related outcomesBlood flow changesMyocardial blood flow changesCardiovascular disease-related outcomesMicrovascular dysfunctionClinical impactCPAPReviewRecent studiesStructural abnormalitiesCoronary microcirculationFindingsRecent studiesFlow reserveCardiac workBlood flowApneaClinical physiology: the crucial role of MRI in evaluation of peripheral artery disease
Elsaid N, Peters D, Galiana G, Sinusas A. Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease. AJP Heart And Circulatory Physiology 2024, 326: h1304-h1323. PMID: 38517227, PMCID: PMC11381027, DOI: 10.1152/ajpheart.00533.2023.Peer-Reviewed Original ResearchPeripheral arterial diseaseMagnetic resonance imagingArtery diseaseClinical applicationEvaluation of peripheral arterial diseaseTranslation to clinical researchPre-clinical modelsMedial vascular calcificationDiagnosis of peripheral arterial diseaseExcellent soft tissue contrastPathophysiology of peripheral arterial diseaseAssessment of peripheral arterial diseaseNoninvasive imaging toolMR imaging technologyMR imaging techniquesSoft tissue contrastMultiplanar imaging capabilityAutonomic dysfunctionMicrovascular dysfunctionRisk stratificationPeripheral neuropathyComprehensive physiological assessmentTreatment outcomesVascular calcificationTherapy planning